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Cytokines
Low molecular weight proteins or glycoproteins
released by one cell population in response to
microbes and act as intercellular mediator or
signaling molecules
Their production stimulates different responses
of cells involved in immunity and inflammation
Produce their effect only when they bind to
specific receptors called cell associated
differentiation (CD) antigens
Nomenclature of cytokines
Is based on their cellular sources
Monokines: when produced by mononuclear
phagocytes
Lymphokines: when produced by T
lymphocytes
Interleukins: when produced by leucocytes
and act against other leucocytes
Functions of cytokines