TOXICANTS OF

BIOLOGICAL
ORIGIN
TOXICANTS OF BIOLOGICAL ORIGIN

 THEY ARE THE SUBSTANCES INADVERTELY ADDED

TO THE FOOD

 EXAMPLES OF NATURALLY OCURING ARE:

 AFLATOXIN

 BOTULISM
AFLATOXIN
 AFLATOXINS ARE POISONOUS CARCINOGENS
THAT ARE PRODUCED BY CERTAIN MOLDS
(ASPERGILLUS FLAVUS)WHICH GROWS IN SOIL .

 THEY ARE REGULARLY FOUND IN IMPROPERLY

STORED STAPLE
COMMODITIES(CHILLI,PEPPER,CORN ,WHEAT)

AFLATOXIN THAT ANIMALS FED

ENTERS THE FOOD CONTAMINATED
SUPPLY OF ANIMALS FOOD

THEY PASS AFLATOXIN

PRODUCTS INTO
EGG,MILK,MEAT
 AFTER ENTERING THE BODY ,AFLATOXINS
MAY BE METABOLIZED BY THE LIVER TO A
REACTIVE EPOXIDE INTERMEDIATE AND
BECOME THE LESS HARMFUL AFLATOXIN
M1
 AFLATOXIN PRODUCING MEMBERS OF
ASPERGILLUS ARE COMMON AND
WIDESPREAD IN NATURE
 THEY COLONIZE AND CONTAMINATE
GRAIN BEFORE HARVEST
 THE NATIVE HABIT OF ASPERGILLUS IS IN
SOIL,DECAYING VEGETATION
 TOXIN CAN ALSO FOUND IN MILK OF
ANIMALS
 HUMANS HAVE AN EXTRAORDINARY HIGH
TOLERANCE FOR AFLATOXIN EXPOSURE
CAUSES OF AFLATOXIN IN
HUMANS
 LIVER CIRRHOSIS
 DAMAGE TO KIDNEY ,HEART

 PULMONARY EDEMA(FLUID BUILD UP IN

LUNGS )
 CEREBRAL EDEMA (FLUID BUILD UP IN
BRAIN )
INCHILDREN
 STUNTED GROWTH
 DELAYED DEVELOPMENT
BOTULISM
 THEY ARE CAUSED BY A TOXIN PRODUCED
BY A BACTERIUM CLOSTRIDIUM
BOTULINUM

KINDS OF BOTULISM

 FOODBORNE BOTULISM
 INFANT BOTULISM

 WOUND BOTULISM
FOODBORNE BOTULISM
 THEY ARE CAUSED BY EATING FOODS
CONTAMINATED WITH THE TOXINS
SYMPTOMS OF FOOD BORNE
BOTULISM
 DOUBLE VISION
 BLURRED VISION

 DROOPING EYES

 SLURRED SPEECH

 DIFFICULTY IN SWALLOWING

 DRY MOUTH

 MUSCLE WEAKNESS

 IT IS NOT SPREAD FROM ONE PERSON TO

ANOTHER
 IT CAN OCCUR IN ALL AGE GROUPS
INFANT BOTULISM
 USUALLY AFFECTS BABIES WHO ARE
BETWEEN 3 WEEKS AND 6 MONTHS OLD
 SPORES OF CLOSTRIDIUM BOTULINUM
FOUND IN DIRT AND DUST ARE HARM FOR
KIDS
WOUND BOTULISM
 THEY ARE CAUSED BY TOXIN PRODUCED
FROM A WOUND INFECTED WITH
CLOSTRIDIUM BOTULINUM
THANK YOU

RIYA JOSEPH