DETECTION OF DENGUE VIRUS

SEROTYPES IN RECENT DENGUE

OUTBREAK IN KOLKATA

NAUREEN NAHAR HOSSAIN

Regn. No: 2014009012

Department of Microbiology
WEST BENGAL STATE UNIVERSITY

UNDER THE GUIDANCE

OF
Dr. Provash Chandra Sadhukhan
ICMR-NICED VIRUS LABORATORY, KOLKATA
 Dengue is an acute viral infection with potential fatal complications

 The word “dengue” is derived from the Swahili phrase Ka-dinga pepo,
meaning “cramp-like seizure” and also known as breakbone fever.

 It is found in tropical and subtropical climates worldwide, mostly in urban

and semi-urban areas.

 It is a positive-stranded encapsulated RNA virus belonging to the family

Flaviviridae, genus Flavivirus and are divided into four antigenically distinct
serotypes DENV-1-4
 Virus enter into the gut & replicates.

Infects the salivary glands during an extrinsic incubation period of 8–12 days.

Then virus transmitted to uninfected person through its anticoagulants during

biting.

Virus then replicates in the second person and produces symptoms which
appears after 4-7 days of biting. This is the intrinsic incubation period.