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TUMOR

NEOPLASM

CANCER

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polutant
Artificial
flavor
food

environtment
preserved

X-ray

Free Chemical
radicals

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NEOPLASM

BENIGN MALIGNANT
(_OMA) (_Carcinoma/sarcoma)

•Slow growth •Rapid growth


•Remain localized •Locally invasive
•May have well-developed capsul •No capsul
•Metastasize(-) •Capable of metastasis
•Variable degrres of
differentiation

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NEOPLASIA
A neoplasm is an abnormal mass of tissue,the
growth of which exceeds and is
uncoordinated with that of normal tissues

Irreversible process of uncontrolled cell


growth

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ANAPLASIA
Anaplasia of tumor cells is
defined as lack of
differentiation
Common featutes of anaplasia
include :
Pleiomorphism
Hyperchromatic nuclei
Atypical mitosis
High nuclear :cytoplasmic ratio
Bizarre cells,including giant cells

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Anaplasia

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Malignant neoplasm

invasi

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Carcinoma Paru

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BENIGN NEOPLASM

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THE MAIN OF HISTOLOGIC- HISTOGENETIC
CATEGORIES OF HUMAN NEOPLASM

Tumors often retain many of the histologic features of their tissue


of origin :
Squamous epithelium Squamous carcinoma
Transitional epithelium Transtitional Carcinoma

•Epithelial tumors Carcinoma


•Connective tissue tumors SARCOMA
•Neuroepithelial Glial cells,ect
•Germ cell tumors Germinal tumor

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TERMINOLOGY OF TUMORS

CELL OF
ORIGIN BENIGN MALIGNANT

•Glandular •Adenoma •Adenocarcinoma


•Fibrous tissue •Fibroma •Fibrosarcoma
•Adipose •Lipoma •Liposarcoma
•Bone •Osteoma •Osteosarcoma
•ect •ect

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DYSPLASIA

INTRAEPITHELIAL
NEOPLASIA

CARCINOMA IN SITU

INVASIVE

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INTRAEPITHELIAL
NEOPLASIA

CITOLOGY

•MILD DYSPLASI
•MODERATE DYSPLASIA
•SEVERE DYSPLASIA
PAP’S
smear
•CARCINOMA INSITU
•CIN
•VIN
•PIN

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Malignant tumors

Arise from

MULTI/TOTI- DIFFERENTIATED CELLS


POTENTIAL CELLS

•Carcinomas
•Germ cell tumor •Sarcomas
•Leukemias
•lymphomas

Radiotherapy?

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Malignant tumor

GRADE

STAGE

Prognosis?

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METASTASIZED

•It is a complex process resulting in


the transfer of tumor cells from the
site of origin to distant/another
ogans
•A unique feature of malignant
tumors

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This presentation ,i dedicate to my student
With love

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