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    This study evaluated the association between maternal exposure to outdoor air pollution during different trimesters of pregnancy and the incidence of asthma, allergic rhinitis, and eczema in preschool children. The study found that exposure to nitrogen dioxide during the second trimester was associated with an increased risk of asthma, and exposure during the third trimester was associated with an increased risk of allergic rhinitis. Exposure to nitrogen dioxide during the first trimester was associated with an increased risk of eczema. The study suggests that traffic-related air pollution, rather than industry-related pollution, may be more strongly linked to the rise in childhood allergies.

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    This study evaluated the association between maternal exposure to outdoor air pollution during different trimesters of pregnancy and the incidence of asthma, allergic rhinitis, and eczema in preschool children. The study found that exposure to nitrogen dioxide during the second trimester was associated with an increased risk of asthma, and exposure during the third trimester was associated with an increased risk of allergic rhinitis. Exposure to nitrogen dioxide during the first trimester was associated with an increased risk of eczema. The study suggests that traffic-related air pollution, rather than industry-related pollution, may be more strongly linked to the rise in childhood allergies.

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    15 views11 pages

    Presentasi Jurnal

    Uploaded by

    Widya Ayu Pratiningsih
    This study evaluated the association between maternal exposure to outdoor air pollution during different trimesters of pregnancy and the incidence of asthma, allergic rhinitis, and eczema in preschool children. The study found that exposure to nitrogen dioxide during the second trimester was associated with an increased risk of asthma, and exposure during the third trimester was associated with an increased risk of allergic rhinitis. Exposure to nitrogen dioxide during the first trimester was associated with an increased risk of eczema. The study suggests that traffic-related air pollution, rather than industry-related pollution, may be more strongly linked to the rise in childhood allergies.

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    of 11

    Exposure to Outdoor Air Pollutin During

    Trimesters of Pregnancy and Childhood


    Asthma, Allergic Rhinitis, and Eczema
    Qihong Deng, Chan Lu, Yuguo Li, Jan Sundell, Dan Norback
    June 2016

    Presented by:
    Widya Ayu Pratiningsih
    Ilmu Kesehatan Masyarakat – Minat Kesehatan Lingkungan
    FKKMK UGM 2020
    Introduction
    Hypothesis
    The fetal origins of childhood allergic diseases and
    speculate that diseases originates in spesific trimester of
    pregnancy and is triggered by traffic-related air pollution.

    Objectives

    To evaluated the association between maternal


    exposure to outdoor air pollution during different
    trimesters of pregnancy and incidence of
    asthma, allergic rhinitis, and eczema.
    Materials & Methods
    Prospective Cohort Study
    September 2011-January 2012
    In the kindergartens Changsha, Hunan Province, China

    Exclude:
    Suburban area,
    LBW,
    Questionnair 2598
    Preterm Birth,
    e responses. Multilple Birth,
    [ISAAC & 3-6 years without health
    Swedish DBH] outcomes
    information
    Exposure Confounding Statistical
    Assessment covariates Analysis
    First, second, and Child-related covariates: Multiple logistic
    thrid trimesters Sex, age, birth season, regression models
    breastfeeding
    NO2, SO2, PM10 Multi-pollutant and
    Parent-related covariates:
    State Environmental multi-
    Parental atopy, maternal
    Protection Agency of productive age, parental SES pollutant/trimester
    China models
    (Previous Study) Residential-related
    covariates: OR with 95% CI
    Individual exposure: ETS, new furniture, house Interquartile Range
    Inverse Distance redecoration, visible mold/
    Weighted (IDW) damp stains, condensation on
    windows, mosquito repellent Sensitivity analysis
    used
    R
    E
    S
    U
    L
    T
    RESULTS

    Allergic
    Asthma Rhinitis Eczema

    PM10 not associated PM10 and SO2 not PM10 and SO2 not
    SO2 associated in single associated associated
    pollutant model NO2 associated in multi- NO2 associated in multi-
    NO2 associated in multi- pollutant model pollutant model
    pollutant model OR =1.69(1.03-2.77) OR =1.37 (1.04-1.80)
    OR =1.63(0.99-2.70)
    Specific in third Specific in first
    Specific in second trimester (1.77, 1.09- trimester (1.54, 1.14-
    trimester (1.72, 1.02- 2.89) 2.09)
    2.97)
    Discussion

    Less study focus on prenatal exposure

    Another factor

    Specific semester

    Biologically plausible
    Limitation
    Strength • Questionnaire-based
    studies is the selection
    The study was suggested bias.
    a multi-
    pollutant/trimester • Only considered three
    regression model. criteria air pollutants

    The first study that • Potentially to


    identify the association misclassification of
    between trimester exposure
    specific and air pollution
    exposure. • Bias of exposure
    Conclusion
    Maternal exposure to traffic-
    related air ollutant NO2 during
    pregnancy associated with the
    incidence of allergic diseases in
    preschool children.
    The rapid increase of childhood
    alergies more caused by traffic-
    related air pollutant than
    industry-related air pollution.
    Need further investigation.
    Thank you!

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