Activity Sheet No.

44

SUBJECT Science 10
TYPE OF
Concept Notes, Exercises
ACTIVITY
Activity Title Genetic Coding
 Decode the DNA sequence with
Learning
its RNA complementary strand.
Target
 Create your own DNA sequence.
8
References Internet Sources
SLIDES
Cop
y

Cracking the Hidden Message

Decoding messages is also a key step in gene

expression, in which information from a gene is
read out to build a protein. In this activity, we’ll
take a closer look at the genetic code, in which
allows DNA and RNA sequences to be “decoded”
 READ!
COVID-19 Learning Note:
All living things use the same genetic code, but
some viruses, including coronaviruses, use RNA
instead of DNA to store their code. RNA decoding
works the same way as DNA decoding, with uracil (U)
swapping in for thymine (T). The host cell translates
the viral RNA into amino acids that make up viral
proteins. Detection of this viral RNA is how doctors
verify whether a patient has been infected with this
specific coronavirus.
 Copy
Instructions: Use the following DNA sequences and
write down the corresponding mRNA sequence below it.
Then, use the secret decoder on the next slide to decipher
the hidden message contained in the mRNA..
Example:
T A C C A C A G T A T T
1 Step: (DNA)
st

2nd Step:(mRNA) A U G G U G U C A U A A

Amino acid met val ser stop

Secret code start H i !
 NOTE: Use the genetic code table
first to know the amino acid, then
Try it on your own! use the decoder table to know the
secret code.
1. DNA: T A C A A T U A G C C C A G A T AG A A G T G A T
TTAGAG C GATT
mRNA:
Amino acid:
Secret code:
2. DNA: T A C G G G T A G T A G A T A C C C A T A G T T A
AGGCGAGTCGACAGACT
mRNA:
Amino acid: Copy and
Secret code: answer
 NOTE: Carefully copy the DNA
Try it on your own! sequence. You can do it!

3. DNA: T A C C T C T A G C C C A A G G T T T A G C C C
TTATTTGTTC GTC GACATTAG GTT
C C CTTTAGATAG C C C CTTAGTGTT
C TAT TAA C T
mRNA:
Amino acid:
Secret code:
Copy and
answer
 NOTE: Patience is the key! Don’t depend
on your classmates’ answer. The feeling of
Try it on your own! fulfilment is different when you answer the
exercise on your own.
4. DNA: T A C G T C T A G T A G C C C G C G C G T C T A
C C C T TA C G T C G T C G A C AT G T TAA G G A C
TA G C C C T T T TA G C G AAT T
mRNA:
Amino acid:
Secret code:
5. Create your own DNA sequence and leave a secret
message for your Science teacher. Comment your DNA
sequence in the comment box. Copy and
answer