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Control of the
Internal Environment
Fig 2.2
(c) 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Blood Pressure at Rest
Fig 2.3
(c) 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Control Systems of the Body
Goal
To regulate some physiological variable
at or near constant value
Room Temperature
Room Thermostat set
Signals thermostat
temperature at 200 C
To turn off heat
Returns to 200 C
Heating System
Fig 2.4
(c) 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Biological Control Systems
Series of interconnected components that
serve to maintain a physical or chemical
parameter at or near constant
Receptor
Capable of detecting changes
Integrating center
Assesses input and initiates response
Effector
Corrects changes to internal environment
Fig 2.5
(c) 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Negative Feedback
Most biological control systems
Response reverses the initial disturbance
in homeostasis
Fig 2.6
(c) 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Example:
Regulation of Blood Glucose
Fig 2.7
(c) 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Example:
Cellular Stress Response
Fig 2.8
(c) 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Exercise: A Test of Homeostatic
Control
Submaximal exercise in a cool
environment
The body’s control systems can maintain
steady state
Maximal exercise or exercise in a
hot/humid environment
May not be able to maintain steady state
Severe disturbances in homeostasis can
occur