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Chapter 01

Lecture Outline
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Anatomy & Physiology

• Anatomy: The study of the structure/morphology of the


human body and its parts
• Physiology: The study of the functions of the human body
and its parts
• The structure of organs and parts of the human body
determines the function.

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Levels of Organization

All materials, living or non-living, are composed of chemicals, which


consist of atoms.
• Subatomic Particles: protons, neutrons, and electrons that make up atoms
• Atom: tiny particles that make up chemicals (hydrogen, carbon)
• Molecule: particles consisting of atoms joined together (water, glucose)
• Macromolecule: large particles consisting of molecules (DNA, protein)
• Organelle: functional part of a cell (mitochondrion, lysosome)
• Cell: basic unit of structure and functions (muscle cell or blood cell)
• Tissue: layer or mass of cells with specific function (adipose tissue)
• Organ: group of different tissues with a function (heart, kidney)
• Organ System: group of organs with common function (digestive system)
• Organism: composed of organ systems interacting (human)

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Figure 1.3 Levels of Organization

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Characteristics of Life

• Growth: Increase in cell number and size and increase in


body size
• Reproduction: Production of new cells and organisms
• Responsiveness: Reaction to a change inside or outside
of the body
• Movement: Change in body position or location; motion of
internal organs

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Characteristics of Life

• Respiration: Making energy. Most organisms do it by


taking in oxygen and giving off carbon dioxide
• Digestion: Breaking down food into usable nutrients for
absorption into the blood
• Circulation: Moving chemicals and cells through the body
fluids
• Excretion: Removing waste products

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Homeostasis
Body’s maintenance of a stable internal environment

Receptors - provide
information
Control center - tells what
a particular value should
be
Effectors - causes
responses to change
Negative Feedback Loop internal environment

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Negative Feedback

• Most common type of homeostatic mechanism


• Effectors return conditions toward normal range, and the
deviation from set point lessens
• Called “negative” because the response to the change
moves the variable in the opposite direction of the
deviation from the set point
• Prevents sudden, severe changes in the body
• Examples: Negative feedback controls body temperature,
blood pressure, and glucose level in the blood

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Figure 1.7 Negative Feedback Illustration

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Positive Feedback

• Uncommon feedback mechanism in the body


• The change/deviation is intensified, instead of reversed
• Activity of effector is increased initially, instead of
decreasing
• Short-lived
• Produce unstable conditions
• Used to make changes
• Examples: Blood clotting and the uterine contractions of
childbirth

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Figure 1.8 Positive Feedback Illustration

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Figure 1.10 Major Body Cavities

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Organ Systems: Body Covering, Support, and
Movement

Integumentary System:
• Body covering, protection, body temperature regulation,
sensory reception, production of Vitamin D
Skeletal System:
• Support and movement, framework, protection,
attachment sites, storage of inorganic salts, production of
blood cells
Muscular System:
• Support and movement, main source of body heat, of
posture.

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Figures 1.14 and 1.15 Organ Systems

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Organ Systems: Integration & Coordination

Nervous System:
• Integration and coordination of organ function through
nerve impulses and neurotransmitters; rapid short-term
effects

Endocrine system:
• Integration and coordination of organ function through
chemical messengers called hormones; slower, longer-
lasting effects

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Figure 1.16 Organ Systems

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Organ Systems: Transport

Cardiovascular System:
• Transportation of gases, nutrients, blood cells, hormones
and wastes

Lymphatic System:
• Transportation of fluids from tissue spaces to blood,
carries fats from digestive system to blood, and defends
body against infection

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Figure 1.17: Organ Systems

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Organ Systems: Absorption & Excretion

Digestive System:
• Receives food, breaks down food, absorbs digestion products,
excretes waste

Respiratory System:
• Moves air in and out of body, exchanges gases (oxygen and
carbon dioxide) between blood and air; absorbs oxygen

Urinary System:
• Removes blood wastes, regulates electrolyte & water balance
and blood pressure, produces urine and excretes it by
transporting it to outside of body

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Figure 1.18 Organ Systems

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Organ Systems: Reproduction

Reproductive System:
• Male and female systems produce and transport sex cells,
produce hormones, and produce new like organisms.
Female also provides for fetal development and childbirth.

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Figure 1.19 Organ Systems

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1.8 Anatomical Terminology

Anatomical Position:
• Standing erect, facing forward, upper limbs at the sides,
palms facing forward
• Anatomical terms of relative position are based on a
person standing in anatomical position.

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Figure 1.20 Anatomical Position

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Terms of Relative Position

• Superior (above) / Inferior (below)


• Anterior or ventral (toward the front) / Posterior or dorsal
(toward the back)
• Medial (toward the midline) / Lateral (away from midline)
• Bilateral (paired structures; on both sides)
• Ipsilateral (same side) / Contralateral (opposite sides)
• Proximal (close to point of attachment to trunk) / Distal
(farther from point of attachment to trunk)
• Superficial (close to body surface) / Deep (more internal)

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Figure 1.21 Terms of Relative Position

Aaron Roeth Photography

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Body Sections or Planes

Sagittal section: longitudinal cut that divides body into left


and right portions
• Mid-sagittal/Median section: divides body into equal left
and right portions
• Parasagittal section: sagittal section lateral to midline;
divides body into unequal left and right portions
Transverse or Horizontal section: divides body into
superior and inferior portions
Coronal or Frontal section: longitudinal cut that divides
body into anterior and posterior portions

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Figure 1.22 Body Sections

(top right, middle right): ©Karl Rubin/McGraw-Hill Education; (bottom right): Living Art Enterprises/Science Source; (left): © McGraw-Hill Education/Eric Wise

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Figure 1.25 Abdominal Regions and Quadrants

(a, b): Juice Images/Alamy Stock Photo

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