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Rahul Baranwal
(Team Leader)
Amit Deb
Vijay Shetty
Devasis Pati
Pharmaceutical Industry – Analysis & Strategy
Ankur Dubey
• Pfizer Inc. is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The
company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer (1824–1906) and his cousin Charles F. Erhart (1821–1891)
• Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company's largest products by
sales are the Pfizer–BioNTech COVID-19 vaccine ($37 billion in 2022 revenues), Nirmatrelvir/ritonavir ($18 billion in 2022 revenues), Apixaban ($6 billion in
2022 revenues), a pneumococcal conjugate vaccine ($6 billion in 2022 revenues), and Palbociclib ($5 billion in 2022 revenues). In 2022, 42% of the company's
revenues came from the United States, 8% from Japan, and 50% from other countries
• Pfizer was a component of the Dow Jones Industrial Average stock market index from 2004 to August 2020. The company ranks 43rd on the Fortune 500 and
43rd on the Forbes Global 2000
Increasing competition:
New medications are constantly being financed, developed, approved and marketed, resulting in significant market growth.
The global pharmaceutical industry continues to grow with Mergers and acquisitions (M&A) are gradually changing the
marketplace and some of the largest pharma companies planned to join forces with other businesses.
Patent expirations:
Several of Pfizer’s top-selling products will confront the loss of key U.S. patents beginning in 2025.
The combined sales for these products contributed more than half of Pfizer’s revenue.
On the other hand, Pfizer has other products and pipeline programs to offset losses.
Regulatory pressures:
The combined efforts of different countries and regulatory bodies, as well as the size of the fines and their gradual ramping up over time, clearly demonstrates the increased risk
pharmaceutical companies are facing today. Several billion dollar fines have been implemented to Pharmaceutical firms for non compliance:
In 2009, Eli Lily was fined $1.42 billion over the promotion of the antipsychotic drug Zyprexa among elderly populations to treat dementia.
In 2009, Pfizer was fined $2.3 billion to misbranding the painkiller Bextra to promote its use as a painkiller in dosages that the FDA deemed dangerously high.
In 2011, Merck agreed to pay almost $1 billion for the illegal promotion of the painkiller Vioxx for the treatment of rheumatoid arthritis when it had not been approved as such.
In 2013, Johnson & Johnson was fined $2.2 billion to resolve allegations around the drugs Risperdal, Invega and Natrecor.
In 2014, The European Commission fined €427.7 million to Servier and five generic drug manufacturers for breaches of rules on restrictive agreements aimed at keeping cheaper medicines.
There is a growing trend in the pharmaceutical industry where drugs are priced
based on their effectiveness and the value they provide to patients. While this
could lead to higher prices for some drugs, it could also pressure the
profitability of drugs that are not seen as providing significant value.
Pfizer’s Position
Pfizer’s R & D Investment over the Years
Ways Pfizer can react to
industry trends and
challenges:
Invest in R & D
Develop Strategic
Partnerships
Acquiring other
Pharma Cos.
Improving Cost
efficiency
• Investing in research and development: Pfizer can • Acquiring other pharmaceutical companies: Pfizer can acquire other pharmaceutical
invest heavily in research and development to companies to expand its product portfolio and diversify its revenue streams. This can help
create new drugs and therapies that address unmet Pfizer mitigate the risk of patent expirations and competition from generic drugs.
medical needs and keep up with changing trends in • Expanding into emerging markets: Pfizer can expand its presence in emerging markets by
healthcare. investing in local infrastructure, forming partnerships with local companies and
• Developing strategic partnerships: Pfizer can form governments, and adapting its marketing and distribution strategies to suit local needs.
strategic partnerships with other companies in the • Improving cost efficiency: Pfizer can work to improve the efficiency of its operations to
industry, as well as with academic institutions and reduce costs and increase profitability. This can include streamlining its supply chain,
research organizations, to leverage their expertise improving manufacturing processes, and adopting new technologies to increase productivity.
and resources to address emerging challenges.
https://bstrategyhub.com/pfizer-mission-statement-vision-core-values-analysis/
https://en.wikipedia.org/wiki/Pfizer
https://services.hbsp.harvard.edu/api/courses/978674/items/W19390-PDF-ENG/sclinks/cb55ad5e930ff39264b319bb67b10
88d
https://www.mckinsey.com/capabilities/operations/our-insights/emerging-from-disruption-the-future-of-pharma-operations
-strategy
https://www.proclinical.com/blogs/2022-6/who-are-the-top-10-pharma-companies-in-the-world-2022
https://www.drugpatentwatch.com/p/applicant/Pfizer
https://www.citybiz.co/article/151654/heres-a-chart-that-every-pfizer-investor-needs-to-see/
https://www.lexisnexis.com/blogs/gb/b/compliance-risk-due-diligence/posts/fine-time-for-pharma-why-due-diligence-is-i
mportant