SISTIM PEREDARAN DARAH

SEL DARAH
SEL DARAH
A. HUMORAL (PLASMA)
 Mengandung air (92%) dan padat (7-9%), protein = albumin,
globulin, fibrinogen
B. SELULAR (SEL DARAH)

1. ERITROSIT
- SEL BULAT TELUR + INTI
- ERITROSIT MATUR --> Hb >>
- JUMLAH ± 3-6 JT/ MM3
- POLYKROMATOSIT 1% DR TOTAL
Erythrocytes
• Primary Function: Oxygen transport
• Elongated elliptical cell: 13-16 m
long by 7-10 wide m
• Nucleus centrally located, elliptical in
shape
• Polychromatins- Immature
erythrocytes-
less elliptical with blueish-gray
cytoplasm
 2. LEUKOSIT
- GRANULOSIT & AGRANULOSIT
LEUKOSIT :
JML > MANUSIA

EOSINOFIL, NETROFIL, MONOSIT --> LEUKOSIT FAGOSIT

FAGOSITIK LEMAH
OUT PSEUDOPODI

MAKROFAG --> LISOSOM MELEKAT

PD VESIKEL OUT ENZIM AS HIDROLASE
KE DALAM VESIKEL

LIMPOSIT --> TIDAK FAGOSITIK (BTK ANTIBODI)

 Monocytes and Macrophages

• Monocytes- large 9-25 m

• Indistinguishable from Macrophages once
in tissue
• Cytoplasm often has granules and a large
nucleus
• Macrophages not usually seen in blood
 Neutrophils (Polymorphonuclear
Leukocytes)
• Only granulocytic leukocyte
present in rainbow trout
• Origin and function of
theses cells not well
understood
• Accounts for 1-9% of total
leukocytes
• Average diameter is 9-13
m
• Multi-lobuated nucleus (2-5
lobes)
 Lymphocytes
• Usually sparse in red
blood cells
• Spherical in shape, 7-10
m
• Eccentrically located
spherical nucleus- stains
reddish-purple
 Thrombocytes
• Occur in varying shapes and
size: elongated, spiked,
fusiform, and spheroid.
• Elongated - 5-8 m long
• Spiked – streaked cytoplasm
on one end
• Fusiform- streaked
cytoplasm on both ends
• Spheroid- dense nuclei,
little or no cytoplasm
TROMBOSIT

- PERAN DALAM PEMBEKUAN DARAH & KEHILANGAN

CAIRAN TB PADA KERUSAKAN (HOMEOTASIS)

-KOMPONEN PEMBEKUAN DARAH

ENZIM PENGHASIL SERABUT FIBRIN DR FIBRINOGEN

SEL2 DRH YANG MJD PEREKAT UTK MENYUMBAT
SISTIM ENZIM FIBRINOLITIK, MELARUTKAN BEKUAN

MASALAH : IKAN --> AIR MELARUTKAN ENZIM

PEMBEKUAN SPONTAN, LAMBAT PD
OTOT PUTIH (LAKTAT)