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NATURAL HISTORY OF GOUT

ARTHRITIS
PERJALANAN GOUT
Hiperurisemia
tanpa gejala Asam urat >6,8 mg/dL
klinis
Serangan akut pertama
Serangan gout paling sering pada MTP1
akut (podagra)
Perjalanan
Gout Fase asimptomatik di
Fase interkritikal antara 2 serangan gout
akut
Destruksi kronis pada sendi
Artritis gout
Deformitas sendi
kronis
Tofus
Pedoman Diagnosis dan Pengelolaan Gout. Jakarta: Perhimpunan Reumatologi Indonesia; 2018.
Although most untreated cases of gout progress to chronic tophaceous gout, the course varies considerably from one patient to another. Whereas some
patients experience only one or two attacks of acute gouty arthritis during their lifetime, over 80% have a second flare within 2 years of the first. It is
quite unusual for tophi to develop in a patient with no history of acute gouty arthritis.

The initial episode of acute gouty arthritis usually follows 10–30 years of asymptomatic hyperuricemia, and there is no evidence that damage occurs to
any organ system during that time.
TERIMA KASIH

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