XII.

Drug Study Mechanism of Action Indication Contraindication Adverse Reactions Nausea Vomiting Stomach pain H Prevention or treatment of infection; signs and symptoms Heartburn of infection like fever an pain are reduced. Diarrhea Feeling an urgent need to urinate Headache Hives Difficulty breathing or swallowing Hoarseness or throat tightness Rapid, irregular, or pounding heartbeat Fainting Fever Joint or E Twice a day exactly at 6 am and 12 noon; Make sure to drink plenty of water or other fluids everyday while taking Ciprofloxacine; Do not take or eat a lot of caffeine products such as coffee, tea, energy drinks, cola or chocolate within 6 hours before or 2 hours after you take ciprofloxacin. C - Instruct client to report any adverse reaction to the physician or nurse. Tell patient that antacids and mineral supplements may decrease the absorption of Ciprofloxacin which makes it less effective when taken at the same time. Nursing Responsibilities C Antibacterial Nursing Implication Instruct patient not to take ciprofloxacin with dairy products such as milk or yogurt, or with calciumfortified juice. He may eat or drink dairy products or calcium-fortified juice with a regular meal, but do not use them alone when taking ciprofloxacin. They could make the medication less effective. Tell patient that Ciprofloxacin can cause side effects that may impair his thinking or reactions. Tell patient to be careful if he plans to drive or do anything that requires him to be awake and alert. Instruct patient to take ciprofloxacin with a full glass of water (8 ounces). Instruct patient to avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 6

Generic Name: Ciprofloxacin Brand name: Quinosyn Classification: Antibacterial

Dosage: 500mg Frequency: BID Route: Per Orem

Source: Nursing 2007 Drug Handbook 27th Edition, Lippincot Williams & Wilkins

Inhibition of topoisomerase (DNA gyrase) enzymes, which inhibits relaxation of supercoiled DNA and promotes breakage of double stranded DNA.

Ciprofloxacin is Ciprofloxacin is contraindicated in used to treat persons with a infections of the history of skin, lungs, airways, bones, and hypersensitivity to ciprofloxacin, any joints caused by member of the susceptible quinolone class of bacteria. antimicrobial agents, Ciprofloxacin is also frequently used or any of the product components. to treat urinary infections caused by bacteria such as Coadministration E. coli. of ciprofloxacin with Ciprofloxacin is effective in treating other drugs primarily infectious diarrheas metabolized by CYP1A2 results in caused by E. coli, increased plasma Campylobacter concentrations of jejuni, and Shigella these drugs and bacteria. could lead to clinically significant adverse events of the coadministered drug. Contraindicated for the treatment of certain sexually

transmitted diseases by some experts due to bacterial resistance. Concomitant administration with tizanidine is contraindicated.

muscle pain Unusual bruising or bleeding Extreme tiredness Lack of energy of appetite Seizures Dizziness Confusion Nervousness Restlessness Anxiety Difficulty falling asleep or staying asleep Pain in the upper right part of the stomach Yellowing of the skin or eyes Dark urine K - Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

hours before or 2 hours after you take ciprofloxacin. These other medicines can make ciprofloxacin much less effective when taken at the same time. Inform patient that Ciprofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take an oral steroid medication, or if you have had a kidney, heart, or lung transplant. Instruct patient to stop taking ciprofloxacin and call the doctor at once if he has sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Also instruct patient to rest his joint until he receive medical care or instructions.