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  • BIO375 Worksheet#1: Pylori Infection. However, After Weeks of Staring at Figure 1 and Mourning, Your Tutor

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    1. Your BIO375 tutor tested positive for H. pylori but feels healthy without ulcers. This could be because 1) the infection is recent, 2) the strain is less virulent, or 3) the tutor has protective stomach acid levels. 2. H. pylori lives in the stomach by producing large amounts of urease that break down urea to ammonia, raising pH and protecting itself from acid. Diagnostically, a urease test confirms H. pylori infection. 3. If the H. pylori strain produced a more potent urease, it could more effectively raise the stomach pH and possibly cause worse infection outcomes like increased ulcer risk

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    Infectious Diseases

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    Worksheet 1

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    1. Your BIO375 tutor tested positive for H. pylori but feels healthy without ulcers. This could be because 1) the infection is recent, 2) the strain is less virulent, or 3) the tutor has protective stomach acid levels. 2. H. pylori lives in the stomach by producing large amounts of urease that break down urea to ammonia, raising pH and protecting itself from acid. Diagnostically, a urease test confirms H. pylori infection. 3. If the H. pylori strain produced a more potent urease, it could more effectively raise the stomach pH and possibly cause worse infection outcomes like increased ulcer risk

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    © All Rights Reserved
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    20 views2 pages

    BIO375 Worksheet#1: Pylori Infection. However, After Weeks of Staring at Figure 1 and Mourning, Your Tutor

    Uploaded by

    Chris
    1. Your BIO375 tutor tested positive for H. pylori but feels healthy without ulcers. This could be because 1) the infection is recent, 2) the strain is less virulent, or 3) the tutor has protective stomach acid levels. 2. H. pylori lives in the stomach by producing large amounts of urease that break down urea to ammonia, raising pH and protecting itself from acid. Diagnostically, a urease test confirms H. pylori infection. 3. If the H. pylori strain produced a more potent urease, it could more effectively raise the stomach pH and possibly cause worse infection outcomes like increased ulcer risk

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    BIO375 Worksheet#1

    Figure 1: The sinister H. pylori caught in action


    (Photo courtesy of scopeblog.stanford.edu)
    1. In a drastic turn of events, your unfortunate BIO375 tutor tested positive for an active H.
    pylori infection. However, after weeks of staring at Figure 1 and mourning, your tutor
    still feels healthy and ulcer-free. Provide at least 3 explanations for this seemingly
    contradictory finding.

    2. What mechanism allows H. pylori to live in the stomach of its host? What is the
    diagnostic significance of this mechanism? Feel free to illustrate your answer

    3. Suppose the H. pylori strain from question 1 harbored a virus in the lytic stage, and this
    virus contained genes coding for a more potent urease enzyme. What outcome would you
    predict?

    4. If an RNA virus you were studying was found to integrate itself into the host cell
    genome, what machinery/tools would you expect this virus to have?

    5. Illustrate the AB model, which is true for the majority of exotoxins.

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