DRUG STUDY

DRUG NAME GENERAL MECHANISM OF INDICATIONS CONTRAINDICATIONS SIDE EFFECTS NURSING CONSIDERATIONS
CLASSIFICATION ACTION
Ceftriaxone Cephalosporin, The cephalosporins >general >hypersensitivity >diarrhea >do not mix drug with
sodium 2 third interfere with a infections to cephalosporins >rash other antibiotics
grams IV OD generation final step in the >meningitis or related >eosinphilia >ensure for an ANST
in 90cc formation of the >gonococcal antibiotics >nausea >monitor renal or
D5Water to bacterial cell wall conjunctivitis LFTs, coagulation
run for 1 (inhibition of >preoperative studies
hour at 10 mucopeptide for prophylaxis > tell patient to report
microdrops biosynthesis), of infection in lack of response and
per minute resulting in surgery adverse side effects
unstable cell
membranes that
undergo lysis. Also,
cell division and
growth are
inhibited. The
cephalosporins are
most effective
against young,
rapidly dividing
organisms and are
considered
bactericidal

Generally, third
generation
cephalosporins
have more activity
against gram-
negative organisms
and less activity
against gram-
positive organisms
than first-
generation drugs.
Third generation
cephalosporins are
also stable against
beta-lactamases.
Cephalosporins can
be destroyed by
cephalosporinase.
Azithromyci Antibiotic, A macrolide >mild to >hypersensitivity >abdominal >obtain an ECG result
n 500 macrolide antibiotic derived moderate to azithromycin, or pain >obtain a culture and
mg/tab 1 from erythromycin. acute bacterial any macrolide discomfort sensitivity
tab OD Acts by binding to exacerbations antibiotic or >nausea and >obtain CBC, liver or
the P site of the of COPD erythromycin vomiting renal function studies
50S ribosomal >mild CAP >anorexia and cultures when
subunit and may >second line >diarrhea/lo warranted