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Drugsafety ANALGETIK
DES 26

Posted by dr.Rozi Abdullah

DAFTAR OBAT AMAN DAN BERBAHAYA UNTUK IBU HAMIL DAN MENYUSUI
ANALGETIK

Nama Obat Risiko Kehamilan Risiko Menyusui

Acetaminophen (Tylenol) B L1

C (1st, 2nd trim.)

Aspirin D (3rd trim.) L3

Azapropazone (Rheumox) L2

Butalbital (Fioricet, Fiorinal,

Bancap, Two-dyne) D L3

B (1st, 2nd trim.)

Butorphanol (Stadol) D (3rd trim.) L3

Celecoxib (Celebrex)) C L2

Codeine (in Tylenol #3, #4) C L3

Colchicine D L4

Diclofenac (Cataflam, Voltaren) B L2

Fentanyl (Sublimaze) B L2

Flurbiprofen (Ansaid, Froben, B (1st, 2nd trim.)

Ocufen) C (3rd trim.) L2

Hydrocodone (Lortab, Vicodin) B L3

Hydromorphone(Dilaudid) C L3

Ibuprofen (Advil, Nuprin, Motrin, B (1st, 2nd trim.)

Pediaprofen) D (3rd trim.) L1
 B (1st, 2nd trim.)
Indomethacin (Indocin) D (3rd trim.) L3

B (1st, 2nd trim.)

Ketorolac (Toradol, Acular) D (3rd trim.) L2

L2;
Meperidine (Demerol) B L3 early postpartum

Methadone (Dolophine) B L3

Morphine (Duramorph,
Infumorph, Epimorph, MS Contin) B L3

Nalbuphine (Nubain) B L2

Naproxen (Anaprox, Naprosyn, L3;

Naproxen, Aleve) B L4 for chronic use

NR
Nefopam (Acupan)

Oxycodone (Tylox,
Percodan,Oxycontin, Roxicet,
Endocet, Roxiprin, Percocet) B L3

Pentosan polysulfate(Elmiron) B L2

Piroxicam (Feldene) B L2

Propoxyphene(Darvocet N,
Propacet, Darvon) C L2

Secobarbital (Seconal) D L3

Tolmetin (Tolectin) C L3

Tramadol HCL(Ultram, Ultracet) C L3

B (1st, 2nd trim.)

Butorphanol D (3rd trim.) L3

Codeine C L3
 Fentanyl B L2

L2
Meperidine B L3 (if used early postpartum)

Methadone B L3

Morphine B L3

Propoxyphene C L2

** Per Medications and Mothers Milk by Thomas Hale, PhD (2004 edition).
Lactation Risk Categories Pregnancy Risk Categories

L1 (safest)
L2 (safer)
L3 (moderately safe)
L4 (possibly hazardous)
L5 (contraindicated)
A (controlled studies show no risk)
B (no evidence of risk in humans)
C (risk cannot be ruled out)
D (positive evidence of risk)
X (contraindicated in pregnancy)