Pyrazinamide

Side Effects/
Contraindicatio
Drug Name Dosage Action Indication Adverse Nursing Resp.
n Effects
Pyrazinami 250 Pyrazinoic the initial - Severe - Fever - Observe and supervise
de mg/5ml acid amide, treatment Hepatic - Poryphori closely.
IV OD analog of of active Damage a - Obtain liver function tests
nicotinami tuberculosi - Hypersensitivi - Dysuria prior to and at 24 wk
de which is s in adults -
ty intervals during therapy.
- Monitor blood glucose
and Acute Gout
bacteriostat children (diabetics) for possible
ic against when loss of glycemic control.
Mycobacte combined
rium with other
tuberculosi antitubercu
s lous agents.

Cefuroxime
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Nursing Resp.
Effects
Cefuroxime 575 mg Semisynthe Infections Hypersensitivity - Thrombo - Determine history of
IV Q8 tic second- caused by to phlebitis hypersensitivity
generation susceptibl cephalosporins. - pain reactions to
cephalospor e - rash cephalosporins,
in antibiotic organism - Increase penicillins, and history
with s in the serum of allergies,
structure lower creatinin particularly to drugs,
similar to respirator e before therapy is
that of the y tract, initiated.
penicillins. urinary - Inspect IM and IV
tract, injection sites
skin, and frequently for signs of
skin phlebitis.
structures
 Isoniazid
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Nursing Resp.
Effects
Isoniazid 200mg/ Hydrazide Treatmen - Hepatic - Irritation - Monitor for visual
5ml IV of t of all injury - fever disturbances
OD isonicotinic forms of - acute liver - weakness - Monitor BP
acid with active damage - Dizziness
highly tuberculo - Nausea
specific sis caused - Blurry
action by vision
against susceptibl
Mycobacter e
ium organism
tuberculosis s and as
preventiv
e in high-
risk
persons

Rifampicin
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Nursing Resp.
Effects
Rifampicin 250mg/ Semisynthe Initial - Obstructive - Fatigue - Check prothrombin
5ml IV tic treatment biliary - Drowsine time daily or as
OD derivative and disease ss necessary to establish
of retreatme - meningococc - headache and maintain required
rifamycin nt of al disease - ataxia anticoagulant activity
B, an clinical - intermittent - confusio when patient is also
antibiotic tuberculo rifampin n receiving an
derived sis therapy. - heartburn anticoagulant.
from - flu-like
Streptococc syndrom
us e
mediterrane
i
 Ethambutol
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Nursing Resp.
Effects
Ethambutol 400mg The In - Optic neuritis - Headache - Perform
1 tab emergence conjuncti - hypersensitivi - dizzines ophthalmoscopic
OD of resistant on with at ty to - confusion examination prior to
strains is least one ethambutol - hallucinat and at monthly
delayed by other ions intervals during
administeri antituberc - paresthes therapy.
ng ulosis ias - Notify physician
ethambutol agent in - joint promptly of the onset
in treatment pains of blurred vision,
combinatio of changes in color
n with other pulmonar perception,
antitubercul y constriction of visual
osis drugs. tuberculo fields, or any other
sis. visual symptoms.
Have eyes checked
periodically.
Ethambutol can cause
irreversible blindness
due to optic neuritis.

Salbutamol
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Nursing Resp.
Effects
Salbutamol 1 neb Produces To relieve N/A - Hypersen Monitor for: S&S of fine
Q6 bronchodil bronchos sitivity tremor in fingers, which
ation, pasm - tremor may interfere with
regardless associate - anxiety precision handwork;
of d with - headache CNS stimulation,
administrat acute or - hallucinat particularly in children
ion route, chronic ions 26 y, (hyperactivity,
by relaxing asthma, excitement, nervousness,
smooth bronchitis insomnia), tachycardia,
muscles of , or other GI symptoms. Report
bronchial reversible promptly to physician.
tree. obstructiv
e airway
diseases.
 Omeprazole
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Nursing Resp.
Effects
Omeprazole 20mg An Duodenal - Long-term - Headache Report any changes in
IV OD antisecreto and use for - Dizziness urinary elimination such
ry gastric (GERD) - Fatigue as pain or discomfort
compound ulcer. - Duodenal - Diarrhea associated with
that is a Gastroeso ulcers - Abdomin urination, or blood in
gastric acid phageal al Pain urine.
pump reflux
inhibitor. disease
Suppresses including
gastric acid severe
secretion erosive
by esophagit
inhibiting is
the H+, K+-
ATPase
enzyme
system in
the parietal
cells.

Oxacillin
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Nursing Resp.
Effects
Oxacillin 375mg Semisynth May be Hypersensitivity - Thrombo - Ask patient prior to
IV Q6 etic, acid- used to to penicillins or phlebitis first dose about
stable, initiate cephalosporins. - wheezing hypersensitivity
penicillinas therapy in - sneezing reactions to
e-resistant suspected - nausea penicillins,
isoxazolyl staphyloc - diarrhea cephalosporins, and
penicillin. occal other allergens.
infections
pending
culture
and
sensitivit
y test
results.
 Ferrous Sulfate
Side Effects/
Drug Dosage Action Indication Contraindication Adverse Nursing Resp.
Name Effects
Ferrous 5ml Corrects To correct - Peptic ulcer - Nausea - Monitor bowel
Sulfate OD PO erythropoie simple iron - regional - heartburn movements as
tic deficiency enteritis - anorexia constipation is a
abnormaliti and to treat - ulcerative - constipati common adverse
es induced iron colitis on effect.
by iron deficiency - hemolytic - diarrhea
deficiency anemias. anemias
but does - hemochromat
not osis
stimulate
erythropoie
sis

Vitamin K
Side Effects/
Drug Dosage Action Indication Contraindication Adverse Nursing Resp.
Name Effects
Vitamin 10mg Fat-soluble antidote for Hypersensitivity - facial Maintain consistency in
K PO naphthoqui overdosage to flushing diet and avoid significant
none of coumarin Aquamephyton - cramp- increases in daily intake
derivative and and severe liver like pains of vitamin Krich foods
chemically indandione disease. - convulsiv when drug regimen is
identical to oral e stabilized.
and with anticoagulant movemen
similar s ts
activity as - chills
naturally - fever
occurring - diaphores
vitamin K is
- weaknes
- dizziness
- shock
 Gentamycin
Side Effects/
Drug Name Dosage Action Indication Contraindication Nursing Resp.
Adverse Effects

Gentamycin 50mg Broad- treatment of hypersensitivity - Ototoxicity - Monitor

IV spectrum serious to or toxic - Optic I&O. Keep
aminoglycos infections of reaction with Neuritis patient well
ide antibiotic GI, respiratory, any - Nausea hydrated to
derived from and urinary aminoglycoside - Vomiting prevent
Micromonos tracts, CNS, antibiotic - Hypotensio chemical
pora bone, skin, and n irritation of
purpurea. soft tissue renal tubules

Hydrocortisone
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Effects Nursing Resp.

Hydrocortis 50mg Acts as an Replacement Hypersensitivity - Malaise - Monitor for

one IV Q6 Anti- therapy in to - Weight gain adverse
inflammator adrenocortical glucocorticoids, - obesity effects
y and insufficiency idiopathic - enuresis - Monitor for
Immunosup thrombocytopen - vertigo persistent
presive ic purpura, - headache backache or
psychoses, acute chest pain
glomerulonephri
tis, viral or
bacterial
diseases of skin

Paracetamol
Side Effects/
Drug Name Dosage Action Indication Contraindication Adverse Effects Nursing Resp.

Paracetamo 400mg Reduces Fever Hypersensitivity - Anorexia - Monitor for s/s

l IV Q6 fever by reduction. to - nausea of
direct action Temporary acetaminophen - vomiting hepatotoxicity
on relief of mild or phenacetin; - dizziness
hypothalamu to moderate use with - lethargy
s heat- pain. alcohol. - diaphoresis
regulating - chills
center with
consequent
peripheral
vasodilation,
sweating,
and
dissipation
of heat.
 Incorporated Budosenide
Drug Side Effects/
Dosage Action Indication Contraindication Adverse Effects Nursing Resp.
Name
Incorpo 1/2 amp Has potent Treatment of Hypersensitivity - Arthralgia Monitor patients
rated glucocortico allergic and to budesonide, - fatigue with moderate
Budose id and weak perennial lactation. - fever to severe liver
nide mineralocort rhinitis, - hyperkinesi disease for
icoid activity maintain s increased S&S
remission in - myalgia of
mild to - asthenia hypercorticism
moderate - paresthesia
Crohn's - tremor
disease; - headache
prophylaxis - dizziness
for asthma. - agitation