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fucole paran

acetaMINOPHEN(PARAN) 500MG

Acetaminophen

TAB

ATC7 N02BE01 paracetamol

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( )


4325~650mg 4~6 1 g438.5
4~65

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3. 15Omg/Kg

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3. 3
4.
5. : Acetaminophen
Acetaminophen
MEDICON-A

Dextromethorphan,LysozymeCresolsulfonate

CAP

ATC7 R05FA01 opium derivatives and mucolytics

Dextromethorphan HBr 20mg


Potassium Cresolsulfonate 90mg
Lysozyme Chloride 20mg

Dextromethorphan HBr

Potassium Cresolsulfonate

Lysozyme Chloride

(15)31

CNS depressants (eg, hypnotics, sedatives, tranquilizers, antianxiety agents)


Effects of these agents may be enhanced.

MAOIs(monoamine oxidase inhibitors) (eg, isocarboxazid)


Hypertensive crisis may occur. Do not use in patients receiving MAOI therapy or within 14 days of
stopping such treatment. May prolong and intensify the effects of chlorpheniramine.

1.

2. MAOI

ALLERGEN TABLETS 50MG "S.T."


(MEBHYDROLIN)=(NAPADISYLATE)

GOWELL : 1.5
Gowell Tab ()

dihydroxyaluminium allantoinate 50 mg, mg al silicate 450 mg

Treatment of gastric hyperacidity, heartburn & indigestion; relief of
symptoms of heartburn & dyspepsia associated with gastric reflux in
reflux esophagitis & other conditions.

GI effects.

Adult 2 tab tid.



Debilitated patients or those with renal or cardiac impairment,

hypophosphatemia.

May affect absorption of tetracyclines & other medicines.

ROAPOCA : 1.53
D
APO-CAPTO 25MG
25APOTEX
captopril 25mg MICROMEDEX

(C) CARDIOVASCULAR SYSTEM
ATC
(C09) AGENTS ACTING ON THE RENIN-ANGIOTENSIN
Anatomical SYSTEM
Therapeutic (C09A) ACE INHIBITORS, PLAIN ()
Chemical (C09AA) ACE inhibitors, plain ()
Classification
(C09AA01) Captopril ()
(C) CARDIOVASCULAR SYSTEM
ATC
(C09) AGENTS ACTING ON THE RENIN-ANGIOTENSIN
Anatomical SYSTEM
Therapeutic (C09A) ACE INHIBITORS, PLAIN ()
Chemical (C09AA) ACE inhibitors, plain ()
Classification
(C09AA01) Captopril ()



BISACODYL SUPP 10MG

Bisacodyl

SUPP

(1)(2)
X

X
10gm 30
5mg

Onset
Tablets
6 to 10 h.

Suppositories
15 to 60 min.

Milk or antacids
May cause enteric coating of tablets to dissolve, resulting in gastric lining irritation or gastric indigestion.

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4. 12

(610/)
EURODIN 2MG Eszo

Estazolam

TAB

ATC7 N05CD04 estazolam

BZD DiazepamNitrazepam Benzodiazepine


()
Benzodiazepine

1-2 mg

Alcohol, anticonvulsants, antihistamines, barbiturates, MAOIs, narcotics, phenothiazines, psychotropic


drugs
May potentiate the CNS depressant effects of estazolam.

Azole antifungal agents (eg, ketoconazole), cimetidine, disulfiram, oral contraceptives, protease
inhibitors (eg, indinavir)
Estazolam plasma levels may be elevated, increasing the pharmacologic and adverse effects.

Digoxin
May increase serum digoxin concentrations.

Rifamycins (eg, rifampin)


Estazolam plasma levels may be reduced, decreasing the pharmacologic effects.

Theophyllines
May antagonize sedative effects of estazolam.

Ritonavir

Flumazenil
SILENCE 1MG TAB

Lorazepam

. benzodiazepine 12

2. 12mg
3.

2312mg24mg

diazepam -

Alcohol/CNS depressants
Additive CNS depressant effects.

Digoxin
Increased serum digoxin concentrations.

Oral contraceptives
Cl rate of lorazepam may be increased.

Rifampin
Pharmacologic effect of lorazepam may be decreased.

Scopolamine
May result in increased incidence of hallucinations, irrational behavior, and sedation.

Theophyllines
May antagonize sedative effects.

THROUGH 12MG TAB

Sennoside A + B

ATC7
A06AB06 senna glycosides

Rhein anthrone

()1~212612
1/2~1;361/4~1/2;3

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CARDIOLOL 10MG/ Inderal

Propranolol

TAB

ATC7
C07AA05 propranolol

1. 1030mg 34
2.:10-20mg3-43-7320mg

3.:20mg4160-240mg
240mg

4.:120-240mg640mg

5.:10-40mg3-4

6.:20mg3

Distribution
Protein binding is 90%. Readily enters the CNS. Crosses the placenta.

Metabolism
Significant first-pass hepatic metabolism.

1.- 2.-
AV 3.-

Clonidine Clonidin

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Raynauds

2.

AKINFREE 2MG

Biperiden

TAB

ATC7
N04AA02 biperiden

CNS cholinergic synapses ACH

3-41

1.
meperidine, phenothiazines
quinidine

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2.

biperiden
DAMPURINE 25MG()

Bethanechol

TAB

510mg1
50mg1050mg 34

1. -
(asthmalike attacks)
2. -

Cholinergic agents
Possible toxicity because of additive effects.

Ganglionic blocking compounds


Severe hypotension, usually preceded by severe abdominal symptoms.

Quinidine or procainamide
Antagonism of anticholinergic effects of bethanechol.

(1)(2)

LACTUL SYRUP 666MG/ML 60ML

Lactulose

PHR ML

Lactulose ( pH )

(PSE, portal systemic encephalopathy) (


Lactobacillus)

1. 15ml 510 15ml 25 5ml 22.5ml

2. 30ml50ml 23

Absorption
Poorly absorbed from the GI tract when given PO and PR (no enzyme capable of hydrolysis of lactulose is present in
GI tissue).

Metabolism
In the colon, lactulose is broken down primarily to lactic acid. Metabolized in the colon by bacteria.

Elimination
Less than 3% is excreted in the urine. Doses reach the colon virtually unchanged.

Onset
24 to 48 h.

Neomycin, other anti-infectives


May interfere with desired degradation of lactulose and prevent acidification of colonic contents.

Nonabsorbable antacids
May inhibit colonic acidification.

galactose

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2. 2~3
3. 2
BININ-U 5MG()

Haloperidol

AMP

1.Haloperidol butyrophenones (Dopamine)


Haloperidol
Haloperidol ()
(basal ganglion)( nigostriatal bundle)2.Haloperidol

3.Haloperidol
4.(
(Parkinsonism)
5.()
()

25mg48

Absorption
When administered in sesame oil, it results in the slow and sustained release of haloperidol. T max is 6
days after injection. Steady-state plasma concentrations are achieved after the third or fourth dose.

Distribution
The relationship between dose of haloperidol decanoate and plasma haloperidol concentration is
roughly linear for doses below 450 mg.

Elimination
Apparent t is approximately 3 wk for the decanoate and 18 h for oral.

Anesthetics, opiates, alcohol


May increase CNS depressant effects.

Anticholinergics
May increase anticholinergic effects. May worsen schizophrenic symptoms, decrease haloperidol serum
concentrations, and lead to tardive dyskinesia.

Azole antifungal agents (eg, itraconazole)


Plasma levels of haloperidol may be elevated, increasing the risk of side effects.
Carbamazepine
May decrease effects of haloperidol.

Lithium
May induce disorientation, unconsciousness, and extrapyramidal symptoms.

Rifamycins (eg, rifampin)


Plasma levels of haloperidol may be reduced, decreasing the clinical effectiveness.

( Parkinsonism)
Haloperidol

QT

Dopaminenoradrenaline
Haloperidol
benztropine mesylate 1-2

Anxicam 2mg/1ml
ANXICAM INJECTION 2MG/ML (LORAZEPAM)
"SWISS"

LORAZEPAM

1.IM:
a.0.O5mg/kg4mg
b.
2.IV:
a.0.O2mg/1b(O.044mg/kg)2mg
b.50
c.
e.12mg
3.18:
4.50:2 mg
5.IV

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1. BENZODIAZEPINES
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1.2~3
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4.2~4mg
5. Neuroleptices
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1.(phenothiazinesbarbituratesantidepressantsethyl alcohol MAOIs)

2. clozepine
3. Valproic acid 40%50%
4.Probenecid 45%130%50%
5. theophylline aminophylline benzodiazepines
6. loxapine
7. scopolamine
8.
bipIDEN INJ 5MG/ML()

Biperiden

AMP

Biperiden 3( Blood-Brain-Barrier)

10-20mg
2.5-5mg30
10-20mg1mg62mg103mg30

5-10mg5mg

Absorption
29% bioavailable; C max is 4 to 5 mcg/L; T max is 1 to 1.5 h.

Elimination
The t is 18.4 to 24.3 h.

AntiparkinsonQuinidine Tricyclic Antidepressant

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