Lying directly over the radial styloid is the first dorsal compartment of the extensor retinaculum,

which contains the abductor pollicis longus and extensor pollicis brevis tendons.

De Quervain’s tenosynovitis
De Quervain’s disease is a condition of stenosing tenovaginitis involving the sheaths of abductor
pollicis longus and extensor pollicis brevis. It presents as pain over the radial styloid process
where the tendon sheaths lie. At this level the tendons course at an acute angle when the wrist
is radially deviated and the thumb is in vigorous use.

The presence of De Quervain's tenosynovitis is confirmed by a positive Finkelstein's test: pain

over the first dorsal compartment is present when the wrist is ulnarly deviated while the thumb is
held in flexion.

Treatment may require surgical release of the sheath.