DRUGS DRUG ADVERSE MECHANISM CONTRAINDICATION NURSING

CLASSIFICATION EFFECT OF ACTION RESPONSIBILITY

Generic ACE Inhibitor  CV: tachycardia, Blocks ACE  Contraindicated with  Take drug 1
Name: Antihypertensive angina pectoris, from converting allergy to captopril, hour before
Captopril heart failure, MI, angiotensin I to history of meals, do not
Raynauds angiotensin II, a angioedema, take with food.
Brand Name: syndrome, powerful second or third Do not stop
Apo-capto hypotension in vasoconstrictor, trimester of, taking drugs
(CAN), salt – or volume leading to pregnancy without
Caspoten, depleted decreased BP,  Use cautiously with consulting your
Gen-captopril patients decreased renal impairment, health care
(CAN), PMS-  Dermatologic: aldosterone heart failure, salt or provider.
Captopril rash, pruritus, secretion, a volume depletion,  Watch to drop in
(CAN) scalded mouth small increased history of renal blood pressure
sensation, in serum artery stenosis, (occur most
pemphigoidlike potassium level lactation often with
reaction, and sodium and diarrhea,
exfoliative fluids loss, sweating,
dermatitis increased in vomiting, or
 GI: gastric prostaglandin dehydration) if
irritation, synthesis also light-
apthous ulcer, may involved in headedness or
peptic ulcer, the dizziness occur,
dysgeusia, antihypertensive consult your
cholestatic action health care
jaundice, provider
hepatocellular
injury, anorexia,
constipation
Generic Aticoagulant  Dermatologic:  Contraindicated with  This drug must
Name: Loss of hair Heparin hypersensitivity to be given by a
Heparin  Hematologic: inactivates heparin; severe parenteral route
sodium bruising, factor Xa, thrombocytopenia; (cannot taken
injection, thrombocytopen therefore uncontrolled orally)
Heparin ia, elevated inhibiting bleeding; any  Frequent blood
sodium lock AST,ALT levels, thrombus and patient who cannot test are needed
flush solution hyperkalemia clot formation by monitored regularly to determine
 Hypersensitivity: blocking the with blood blood clotting
Brand Name: Chills, fever, convertionof coagulation test; time is within the
Hepalean urticaria, prothrombin to labor and immediate correct range
(CAN), Heparin asthma thrombin and post partum period  Be careful to
Leo (CAN),  Others: fibrinogen to avoid injury: use
Hepalean-Lok Osteoporosis, fibrin, the final an electric razor,
(CAN), suppression of stage in the avoid contact
Hepflush-10, renal function clotting process. sports and avoid
Hep-lock, Hep- ( long term, high Heparin also other activities
Lock U/P dose therapy) inhibits the that might lead to
activation of injury
factor XIII and  You may
thrombin- experience hair
induced loss
activation of  Report nose
factor V and VII bleed, bleeding
gums, unusual
bruising, black or
tarry stools,
cloudy or dark
urine, abdominal
or lower back
pain, severe
Headache
Generic Antidote, Muculytic use Mucolytic Muculytic use  You may
Name: Mucolytic GI: Nausea, activity: splits  Contraindicated with experience these
Acetylcysteine stomatitis links in the hypersensitivity to side effects:
(N- Hypersensitivity: mucoproteine acetylcysteine; use increased
acetylcysteine) Urticaria contained in caution and production
Rspiratory: respiratory discontinue cough, nausea,
Brand Name: Bronchospasm, mucus immediately if GI upset.
Acetadote, especially in secretion, bronchospasm  Report difficulty
mucomyst patient with decreasing the occurs. breathing or
asthma viscosity of the nausea
Antidote Use mucus Antidote use
Dermatologic: Antidote to  No contraindication,
Rash acetaminophen use caution with
GI: Nausea, hepatotoxicity: esophageal varices,
vomiting, other Protect liver peptic ulcer.
GI symptoms cells by by
maintaining cell
function