DRUG THERAPEUTIC RECORD

MECHANISM OF CONTRA- SIDE EFFECTS/

DRUG NAME DRUG CLASS INDICATIONS NURSING CONSIDERATION
ACTION INDICATIONS ADVERSE EFFECTS
Generic: Therapeutic: Inhibition of  Reduction Hypersensitivity to HEMA: Before:
Antiplatelet , platelet of risk of salicylates tatrazin, Thrombocytopenia,  Assess allergy to
Aspirin Nonnarcotic aggregation is recurrent TIAs GI bleeding, aggranulocytosis, salicylates or NSAIDs;
analgesic, attributable to the or stroke in bleeding disorders, leukopenia, neutropenia, allergy to tartrazine;
nonsteroidal anti- inhibition of males with chidren<12 yr, hemolytic anemia hemophilia, bleeding
inflammatory, platelet synthesis history of TIA children with flulike CNS: Stimulation, ulcers, hemorrhagic
antipyretic, of thromboxane due to fibrin symptoms, drowsiness, dizziness, states, blood
A2, a potent platelet emboli Pregnancy (3rd confusion, convulsion, coagulation defects,
Brand: vasoconstrictor  Reduction Trimester), flushing, hallucinations, hypoprothrombinemia,
and inducer of of risk of death lactation, vit K coma vitamin K deficiency;
Arthrinol, platelet or nonfatal MI deficiency, peptic GI: Nausea and vomiting, impaired hepatic
Arthrisin, aggregation. This in patients ulcer GI bleeding, diarrhea, function; impaired renal
Aspergum Bayer effect occurs at with history of heartburn, anorexia, function; chickenpox,
Aspirin, low doses and infarction or Pregnancy hepatitis influenza; children with
Coryphen, lasts for the life of unstable Category: D INTEG: Rash, urticuria, fever accompanied by
Easpirin, Ecotrin, the platelet (8 angina bruising dehydration; surgery
Empirin, days). Higher pectoris EENT: Tinnitus, hearing scheduled within 1 wk;
Entrophen doses inhibit the  MI loss pregnancy; lactation
synthesis of prophylaxis CV: Rapid pulse,  Assess  Skin color,
prostacyclin, a pulmonary edema lesions; T; eighth
potent vasodilator RESP: Wheezing, cranial nerve function,
and inhibitor of hypernea orientation, reflexes,
platelet ENDO: Hypoglycemia, affect; P, BP, perfusion;
aggregation. hyponatremia, R, adventitious sounds;
hypokalemia liver evaluation, bowel
SYST: Reye’s Syndrome sounds; CBC, clotting
times, urinalysis, stool
guaiac, LFTs, renal
function tests

During:
 BLACK BOX
WARNING: Do not use
in children and
teenagers to treat
chickenpox or flu
 symptoms without
review for Reye’s
syndrome, a rare but
fatal disorder.
 Give drug with food or
after meals if GI upset
occurs.
 Give drug with full
glass of water to
reduce risk of tablet or
capsule lodging in the
esophagus.
 Do not crush, and
ensure that patient
does not chew SR
preparations.
 Do not use aspirin that
has a strong vinegar-
like odor.
 WARNING: Institute
emergency procedures
if overdose occurs:
Gastric lavage,
induction of emesis,
activated charcoal,
supportive therapy.

After:
 Monitor patient
response to therapy.
 Monitor for adverse
effects.
 Evaluate patient
understanding on drug
therapy.
 Monitor patient
compliance to drug
therapy.
 Educate patient to take
extra precautions to
 keep this drug out of
the reach of children;
this drug can be very
dangerous for children.
 Inform the patient to
use the drug only as
suggested; avoid
overdose. Avoid the
use of other over-the-
counter drugs while
taking this drug. Many
of these drugs contain
aspirin, and serious
overdose can occur.
 Encourage patient to
report any adverse
effects such as ringing
in the ears; dizziness,
confusion; abdominal
pain; rapid or difficult
breathing; nausea,
vomiting, bloody stools.