NAME OF DRUG MECHANISM OF INDICATION
ACTION
GENERIC NAME: Enoxaparin binds to Indicated for the prevention
Enoxaparine antithrombin III, a of ischemic complications in
BRAND NAME: serine protease unstable angina and in non
Lovenox inhibitor, forming a Q-wave myocardial
ROUTE: complex that infarction
SQ irreversibly inactivates - in conjunction with
FREQUENCY: factor Xa, which is percutaneous intervention
OD frequently used to and/or other treatment for
monitor the management of acute
TIMING: anticoagulation in the ST elevation myocardial
8PM clinical setting. infarction.
- for the inpatient treatment
of DVT with or without
pulmonary embolism and
the treatment of outpatient
DVT without pulmonary
embolism.
Hypersensitivity,
uncontrolled bleeding, GI
bleeding/ulceration/
pathology.
- Retinopathy (hypertensive
or diabetic).
- Untreated hypertension.
- History of congenital or
acquired bleeding disorder.
- Recent history of ulcer
disease.
SIDE EFFECTS NURSING RESPONSIBILITIES
Dizziness, headache, Before:
insomnia, • Remind patient to inform their
constipation, N/V, physician if they have received
urinary retention, Lovenox or heparin before and
bleeding, anemia, had a reaction such as
thrombocytopenia. thrombocytopenia
AE: Hemorrhage During:
(including at the • Assess for signs and symptoms of
injection site), bleeding and hemorrhage
peripheral or • Assess for S & S of thrombosis,
unspecified edema, observe injection sites for
anemia, hematuria, hematomas
ecchymosis, fever, • Avoid playing contact sports or
confusion, nausea, participating in high risk sports
diarrhea, dyspnea, inj. activities
site pain. After:
Potentially Fatal: • Advise patient to report any
Major hemorrhagic symptoms of unusual bleeding to
complications (e.g. health care professional
retroperitoneal and immediately.
intracranial bleeding. • Instruct patient not to take
aspirin, or ibuprofen without
consulting health care
professional while on enoxaparin
therapy.
- Hemorrhagic stroke.