DOSAGE,

ADVERSE NURSING
DRUG NAME ROUTE, ACTION CONTRAINDICATIONS
EFFECTS RESPONSIBILITIES
FREQUENCY

Nitroglycerin Tablet:0.2-0.6 Reduces - hypersensitivity Cardiovascular • Monitor blood pressureand

mg SL q 5 cardiacoxygen tonitroglycerin and :Face and heart rate on aregular basis.
minsfor demand bydecreasing othercomponents neckflushing, • Instruct patient to
orthostatichypo takemedication while
maximum of leftventricularpressure
- closed-angle glaucoma- tension,tachyca sittingdown and to
3doses in 15 andsystemic rdiaCNS:heada changepositions slowly
min vascularresistance; severe anemia
che,restlessness • Instruct patient to allowtablets
dilatescoronary - increased GI:nausea, to dissolve undertongue, and
arteriesand improves intracranialpressure vomiting not to chewor swallow
collateral flow sublingualtablets.Instruct
toischemic regions - head trauma patient to seekemergency help
promptlyif chest pain is
- uncorrected hypovolemia unresolvedafter 15 minutes.
• Instruct patient not tochange
brands withoutconsulting
prescriber.
• Instruct patient to keeptablets
in original, air-tight
container.
• Advise patient to usecaution
when engaging inactivities
requiring mentalalertness.
• Advise patient to reportacute
headache, rapidheartbeat,
unusualrestlessness or
dizziness,or blurring of vision
 DOSAGE,
ADVERSE NURSING
DRUG NAME ROUTE, ACTION CONTRAINDICATIONS
EFFECTS RESPONSIBILITIES
FREQUENCY

Ceftriaxone 450/mg Works byi nhibiting Hypersensitivity to Body as a Assess patient’s

themucopeptidesynthe cephalosporins and related Whole: Pruritus, previoussensitivityreactionto
sis in thebacterial antibiotics; pregnancy fever, chills, penicillin
orothercephalosphorins.
cellwall. The beta- (category B). pain, induration
lactam moietyof at IM injection Assess patient forsigns
Ceftriaxonebinds site; phlebitis andsymptoms of infection
tocarboxypeptidases,e (IV beforeandduring the
ndopeptidases,andtran site). GI: Diarrh treatment
speptidasesin the ea, abdominal
bacterialcytoplasmicm cramps, pseudo
Obtain C&S beforebeginning
embrane. membranous
drugtherapy
Theseenzymes colitis, biliary toidentifyif correcttreatme
areinvolved in cell- sludge. Urogeni nthas beeninitiated.
wall synthesisand cell tal: Genital
division.By binding pruritus;
tothese moniliasis. Report signs suchas
enzymes,Ceftriaxoner petechiae,ecchymotic
areas,epistaxis or otherforms
esults in theformation
of unexplainedbleeding.
of of defective
cellwalls and
celldeath. Monitorhematologic,electroly
tes, renaland
hepaticfunction.

Assess for possiblesupper

infection:itching fever
 DOSAGE,
ADVERSE NURSING
DRUG NAME ROUTE, ACTION CONTRAINDICATIONS
EFFECTS RESPONSIBILITIES
FREQUENCY

Febuxostat PO Start with 40 Decreases serum uric Coadministration with Dizziness, Rash, Instruct patients to contact health
mg once daily. acid by inhibiting azathioprine, Nausea, care provider if they experience
The dosage may xanthine oxidase mercaptopurine, or Abnormal LFTs, chest pain, rash, shortness
ofbreath, or neurologic symptoms
be increased to theophylline. Arthralgia
suggesting a stroke.
80 mg once
daily for
patients who do Advise patients that product may
not achieve a be taken without regard to meals.
serum uric acid
less than 6
mg/dL after 14
days
 DOSAGE,
ADVERSE NURSING
DRUG NAME ROUTE, ACTION CONTRAINDICATIONS
EFFECTS RESPONSIBILITIES
FREQUENCY

Pantoprazole 40 mg vial Specifically, Hypersensitivity to NGI: Diarrhea, • Monitor for and

suppresses gastric acid pantoprazole or other proton flatulence, immediately report S&S
secretion by inhibiting pump inhibitors (PPIs); abdominal pain. of angioedema or a severe
skin reaction.
the acid (proton H+) severe hepatic insufficiency, CNS: Headache,
pump in the parietal cirrhosis. insomnia. Skin:
cells. Rash.
 DOSAGE,
ROUTE, ADVERSE NURSING
DRUG NAME ACTION CONTRAINDICATIONS
FREQUEN EFFECTS RESPONSIBILITIES
CY

Generic Child: IV Sta Hypetension, Patients hypersensitive to CNS-dizziness, >>Monitor patients BP.
Name:Losartan rt with 2 Nephepatically in drug, breast-feeding is not asthenia, >>Monitor patients who are also
Potassium mcg/min, type 2 daibetic recommended,causes fetal fatigue, headach taking diuretics for symptomatic
titrate to patients, to and neonatal morbidity and e, insomia. hypotension.
maintenance reduce risk of deat
dose of 0.1 CVA in patients CV-edema,chest >>Assess patients renal function
mcg/kg/min with pain. >>Tell patient to avoid salt
hypertension and substitutes
EENT-nasal
left ventricular congestion, sinu
hypertrophy sitis,pharyngitis,
sinus disorder.

GI-Abdominal
pain, nausea, dia
rrhea,dyspepsia.
Musculoskeletal
-muscle cramps,
myalgia, back
orleg pain

.Respiratory-
cough,
upperrespiratory
infection
 DOSAGE,
ADVERSE NURSING
DRUG NAME ROUTE, ACTION CONTRAINDICATIONS
EFFECTS RESPONSIBILITIES
FREQUENCY

Acetylcysteine 1 sachet of Treatment of Severe anemia; cardiac Hypersensitivity • Monitor effectiveness of

Acetylcysteine 200 respiratory failure, patients with normal reactions have b therapy and advent of
mg or 2 sachets of affections or increased intravascular een reported in p adverse/allergic effects.
volume. Safety during Instruct patient in
Acetylcysteine100 characterized by atients receiving
pregnancy (category C) or appropriate use and
mg, 2-3 times a thick and lactation is not established. acetylcysteine, adverse effects to report..
day1 viscoushypersecreti including
Acetylcysteine 600 ons: acute bronchospasm,
mg effervescent bronchitis, chronic angioedema,
tablet daily ( bronchitis and its rashes and
preferably in the exacerbations; pruritus, may
evening)For the pulmonaryemphyse occur.
prevention of ma, mucoviscidosis Other adverse
exacerbation, the and bronchiectasis. effects reported
use of include nausea
FLUIMUCIL 200 and vomiting,
mg sachets fever, syncope,
isrecommended. sweating,
Children: Aged up arthralgia, blurre
to 2 years: 1 sachet d vision,
of 200 mg daily or disturbances of
2 sachets of 100 liver function.
mg daily.3-7 years:
1 sachet of 200 mg
twice daily or 2
sachets of 100 mg
twice a day.
 DOSAGE,
ADVERSE NURSING
DRUG NAME ROUTE, ACTION CONTRAINDICATIONS
EFFECTS RESPONSIBILITIES
FREQUENCY

carvedilol Adult: Carvedilol causes Patients with class IV Body as a • Monitor for therapeutic
Initially,12.5 mg vasodilation by decompensated cardiac Whole: Increase effectiveness which is
oncedaily blocking the activity failure, bronchial asthma, or d sweating, indicated by lessening of
of α-blockers, mainly S&S of CHF and
increased to25 related bronchospastic fatigue, chest
at alpha-1receptors. I improved BP control.
mg once exerts anti hypertensiv conditions (e.g., chronic pain, pain,
dailyafter 2 e effect partly by bronchitis and emphysema), arthralgia. CV:
days.Alternative reducing total second- and third-degree Bradycardia,
ly,initial dose of peripheral resistance AV block, cardiogenic hypotension,
6.25 mg and vasodilation. It is shock or severe bradycardia; syncope,
bidincreased to used in patients with pregnancy (category C), hypertension,
renal impairment
12.5mg bid after lactation. AV block,
,NIDDM or IDDM
1-2wk, angina. GI: Diar
increasedfurther rhea, nausea,
if necessary to abdominal pain,
50mg once daily vomiting. Respi
or in divided ratory: Sinusitis
doses. o Elderly ,
: 12.5 mgonce bronchitis. Hem
daily atologic: Throm
bocytopenia, Me
tabolic: Hypergl
ycemia, weight
increase,
gout. CNS: Dizz
iness, headache,
paresthesias.
 DOSAGE,
ADVERSE NURSING
DRUG NAME ROUTE, ACTION CONTRAINDICATIONS
EFFECTS RESPONSIBILITIES
FREQUENCY

Ciprofloxacin 100 mg, 250 Synthetic quinolone Known hypersensitivity to GI: Nausea, • Assess for infectionprior
mg, 500 that is a broad ciprofloxacin or other vomiting, to and duringtherapy.-
mg, 750 spectrum bactericidal quinolones, syphilis, viral diarrhea, • Obtain specimensfor
agent. Inhibits DNA- infection; tendon culture andsensitivity
mg cramps, gas,
gyrase, an enzyme inflammation or tendon beforeinitiating therapy
tablets; necessary for bacterial pain; pregnant women pseudomembran • .First dose may begiven
500 mg DNA replication and (category C), lactation. ous beforereceiving results.
extended some aspects of colitis. Metaboli • Toprevent developmentof
-release transcription, repair, c: Transient resistant bacteria,therapy
tablets; recombination, and increases in liver should onlybe used to
50 transposition transaminases, treatinfections that
areproven or
mg/mL, alkaline
stronglysuspected to
100 phosphatase, becaused bysusceptible
mg/mL lactic bacteria.
suspensi dehydrogenase, • -Observe for signsand
on; 200 and eosinophilia symptoms of anaphylaxis
mg, 400 count. Musculos (rash,pruritus,
mg keletal: Tendon laryngealedema,
wheezing).Discontinue
injection rupture,
drugand notify
; 3.5 cartilage physicianimmediately if
mg/mL erosion. CNS: H theseproblems occur
ophth eadache,
solution vertigo, malaise,
peripheral
neuropathy,
seizures
(especially with
rapid IV
infusion). Skin:
Rash, phlebitis,
pain, burning,
pruritus, and
erythema at
infusion
site. Special
Senses: Local
burning and
discomfort,
crystalline
precipitate on
superficial
portion of
cornea, lid
margin crusting,
scales, foreign
body sensation,
itching, and
conjunctival
hyperemia.
 DOSAGE,
ADVERSE NURSING
DRUG NAME ROUTE, ACTION CONTRAINDICATIONS
EFFECTS RESPONSIBILITIES
FREQUENCY

Clopidogrel 75 mg 1 tab PO Antiplatelet agents Hypersensitivity to Body as a • Carefully monitor for and
OD ;Platelet aggregation clopidogrel; intracranial Whole: Flu-like immediately report S&S
inhibitors hemorrhage, peptic ulcer, or syndrome, of GI bleeding, especially
any other active pathologic when coadministered
fatigue, pain,
bleeding; pregnancy with NSAIDs, aspirin,
(category B). Discontinue arthralgia, back heparin, or warfarin.
clopidogrel 7 d before pain. CV: Chest
surgery and during lactation. pain, edema,
Safety and efficacy not hypertension,
established in children. thrombocytic
purpura. GI: Ab
dominal pain,
dyspepsia,
diarrhea, nausea,
hypercholesterol
emia. Hematolo
gic: Thrombotic
thrombocytopen
ic purpura,
epistaxis. CNS:
Headache,
dizziness,
depression. Res
piratory: URI,
dyspnea,
rhinitis,
bronchitis,
cough. Skin: Ra
sh, pruritus.