Features Down’s Turner’s Klinefelter’s

Syndrome Syndrome Syndrome

Non-disjunction 21st chromosome Sex chromosome Sex chromosome

Chromosome Additional Missing Additional

Number 2n + 1 2n – 1 2n + 1
47 45 47

Chromosomal 45 Autosome + XY = 44 Autosome + Y = 44 Autosome + XXY = 47

relation 47 45

Sex Male or Female Female Male

Gamete 24 22 24

Gamete Ova Egg Sperm

involved
Frequency of 1 / 700 1 / 6,000 1 / 1500
Birth

Frequency of 1 / 40 1 / 18 0
Abortion

Conditions (  Flat  Often do not  Phenotopically

Affected  Broad face survive male
Individuals )  Squint eyes pregnancy  Enlarged breasts
with skin and are  Tendency to tall
folded in the aborted  Small testes
inner corner  Who survive  No sperm at
 Protruding having ejaculation
tongue female  Under
 Mental appearance development of
retardation  Short stature secondary sex
 Defective  Webbed characters
development neck
of C.N.S  Without
ovaries
 Complete
absence of
germ cells