Confidential

Editing Test
INSTRUCTIONS
① Turn on Track Changes
(from Review tab). Edit
in-line and make the
necessary changes to the
text. Do not rewrite the
② ① ③ content separately or
delete complete
USEFUL TIPS sentences, and do not use
1. Address issues with clarity, sentence structure, comments to indicate or
word choice/terminology, grammar, and suggest changes required
punctuation. unless you are unsure of
the author’s intended
2. Use a formal tone and expressions that are meaning at a particular
suitable to research papers. instance.
② Insert comments to flag
3. Do not edit the passage to simply improve the missing information or
quality of the language used. Use Google or unclear instances, or to
Google Scholar to understand concepts or to explain extensive
verify information and spelling. revisions.
③ Switch to Simple
4. Refer to the sample edit given below to Markup and proofread
understand the scope of editing and how the content and the
comments are to be used. comments.
5. You need not refer to the source provided under ④ Save the file as .doc
each passage to do a good job. Use the context or .docx and rename the
provided in the passage itself. file by adding your full
name (e.g., John
Doe_Editing Test)

Contents
Sample Edit (for reference only)................................................................................................ 2
Test Passages ............................................................................................................................. 3
Biomedicine passage 1 ........................................................................................................... 3
Biomedicine passage 2 ........................................................................................................... 4
Confidential

Sample Edit (for reference only)

The aim of this study was to examine the possible serlective advantage of

conferred by red coloration in the shell color of Laqueus rubellus (a terebratulid

brachiopod) was checked in terms of interactions of prey and in predator-prey

interactions. The study was based on comparison of We compared benthic

suspension feeders seen found at a depth of about 130 m depth in Suruga Bay,

Japan, with peculiar reference to focusing particularly on their visibility under

visible and near-infrared light conditions. Our results showed that in visible light,

Aalmost all species exhibited red coloration under visible light, while whereas in

infrared light, only the shell of L.aqueus rubellus was is as dark under infrared light,

similar to as rocks and bioclasts. Provided tThe functional eyes of macropredators
such as fishes and coleoids, which are specialized as for detecting light in the blue-
to-green region of the visible spectrum,, and predators like malacosteids have even
Commented [A1]: “Red” refers to a frequency of light, whereas
“dark” refers to the intensity of light. Therefore, the contrast or
comparison between L. rubellus and other species is not very clear.
Could this part of the sentence be revised as “only the shell of L.
rubellus resembles rocks and bioclasts in color?

the long-wavelength photoreceptors of malacosteids,; however, because of its

unique shell coloration, L.aqueus rubellus should avoid can possibly escape both

visible and infrared detection by these predators living at in the bottom of the

sublittoral bottom zone under both visible and infrared light conditions. This fact Commented [A2]: “Sublittoral bottom zone” may sounds
slightly non-standard. I have revised this term assuming that you are
referring to the sea bottom in the sublittoral zone, here and at
suggests that terebratulids have evolved the ability to remain more or less subsequent instances.

If, however, you are referring to “the deeper sublittoral zone,” please
use this phrase instead everywhere.
essentially invisible with even as the improvements of optic visual detection

abilities of predators have improved.

Confidential

Test Passages

Biomedicine passage 1

Radiotherapy (RT)-related damage to salivary glands has generally been examined using
models of animal radiation; studies involving human subjects are limited. The purpose of the
present study was to examine the temporal changes in parotid volume and apparent diffusion
coefficient (ADC) in NPC patients treated with intensity-modulated RT (IMRT). Eleven
patients, 9 men and 2 females, were enrolled. Radiation therapy, ADC, and parotid sparing
volume was recorded. Magnetic resonance imaging (MRI) studies were acquired at four
stages: once before and thrice after RT. The obtained data were analysed using SPSS and
MedCalc, and for multiple comparisons, an analysis of variance was performed using
ANOVA. P values less than 0.05 were considered statistically significant. The parotid
volume was 25.3 ± 7.0 cm3 before RT but reduced to 27.9 ± 7.2 cm3 at post-RT stages. The
volume reduced to 31.2 ± 13.0%, 26.1 ± 13.5%, and 17.1 ± 16.6% at stages 1, 2, and 3,
respectively. The parathyroid ADC was significantly higher at all post-RT stages than the
pre-RT stage. The percentage increase in ADC was 35.7 ± 17.4, 27.0 ± 12.8, and 20.2 ± 16.6
at post-RT stages 1, 2, and 3, respectively. The decrease in parotid volume and increase in
parotid ADC were affected by acinar loss rather than edema at early stages. In conclusion ,
the temporal changes of parotid volume and ADC quantitative in NPC patients with IMRT
were evaluated. We believe that the subsequent recovery of parotid volume and ADC might
reflect the acinar regeneration of parotid glands.

Time taken to edit (in minutes): __15 minutes

Source: Temporal Evolution of Parotid Volume and Parotid Apparent Diffusion Coefficient in
Nasopharyngeal Carcinoma Patients Treated by Intensity-Modulated Radiotherapy
Investigated by Magnetic Resonance Imaging: A Pilot Study, by Chun-Jung Juan, Cheng-
Chieh Cheng, Su-Chin Chiu, et al., used under CC BY
Confidential

Biomedicine passage 2

Malaria caused approximately 584,000 deaths in 2013. It caused Plasmodium species and
transmitted the female Anopheles mosquito. So far, only 5 of the 170 species of this parasite
have been found which are the cause of disease in humans. They consist of P. falciparum, P.
knowlesi, P. ovale, P. vivax, and P. malariae. Falciparum malaria causes P. malariae, the
most dangerous form that can even lead to death. According to the December 2014 statistics,
198 million cases of malaria and 584,000 associated deaths were recorded in 2013. Since
2000, malaria mortality rates have fallen by 47% globally and by 54% in the WHO African
Region. Researchers are working on new drugs and medicinal plants as therapeutic agents
due to drug resistance that is a major problem facing them. Cinnamon, the inner bark of trees
of the genus Cinnamomum, is reported to have antiparasitic effects. Previous studies have
evaluated the effects of aqueous, hexane, methanol, and ethanol extracts of cinnamon on
gram-positive and negative-bacteria such as yeast, Leishmania, and Toxoplasma.
Metabonomics involves the use of high-throughput technology to measure the metabolic
response of living systems to biological stimuli or genetic manipulation. In this study, the
mechanism underlying the effect of the aqueous extract of cinnamon on the metabolome of P.
falciparum in vitro was determined using 1HNMR spectroscopy. Aqueous extract of
cinnamon added culture of P. falciparum 3D7 and its 50% inhibitory concentration (IC50)
determined, and, after collection of treated parasites, their metabolites extracted. The
metabolites were analyzed by 1HMNR spectroscopy using the NOESY method. The spectra
was analyzed by chemometric methods. The differentiating metabolites were identified using
the Human Metabolome Database, and the metabolic cycles were identified by
MetaboAnalyst. 1.25 mg/mL was determined to be the concentration of inhibitor which
reduced half the parasites. The metabolites identified were succinic acid, glutathione, L-
aspartic acid, beta-alanine, and 2-methylbutyryl glycine. The main metabolic cycles
identified were alanine, aspartate, and glutamate pathway, coenzyme A biosynthesis from
pantothenate, lysine biosynthesis, and glutathone metabolism, all of which are important as
drug targets.

Time taken to edit (in minutes):

Source: The Effect of Aqueous Extract of Cinnamon on the Metabolome of Plasmodium falciparum
Using 1HNMR Spectroscopy by S. Parvazi, S. Sadeghi, M. Azadi, et al., used under CC-BY