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CME

Further Clarification of the Nomenclature for


Compound Flaps
Geoffrey G. Hallock, M.D.
Learning Objectives: After studying this article, the participant should be able to: 1.
Allentown, Pa. Understand the attributes and unique niche for compound flaps and their limitations.
2. Comprehend a proposed schema for further clarifying the classification of all types
of compound flaps that is differentiated on the basis of the distinct vascular supply to
each flap subtype. 3. Appreciate that minor technical modifications of known flaps of
any type in general do not necessarily create a new category of flap.
Background: A unique niche exists for compound flaps because of their extraor-
dinary capability to allow repair of massive defects where the simultaneous resto-
ration of multiple missing tissue components is demanded. The guidelines from the
previous “simplified” classification schema need to be updated to allow a more
complete clarification and further standardization of this concept.
Methods: Compound flaps can be partitioned into two major classes that in turn
are further differentiated into various subtypes according to their inherent pattern
of circulation.
Results: The subdivisions of compound flaps are those with a solitary source of
vascularization and those with combinations of sources of vascularization. Those
with a solitary source include composite flaps, defined as multiple tissue compo-
nents all served by the same single vascular supply, and thereby consisting of
dependent parts. Those flaps with combinations of sources of vascularization in-
clude (1) conjoined flaps, defined as multiple flap territories, dependent because
of some common physical junction, yet each retaining its independent vascular
supply; and (2) chimeric flaps, defined as multiple flap territories, each with an
independent vascular supply, and independent of any physical interconnection
except where linked by a common source vessel.
Conclusions: Although many technical modifications have improved and will im-
prove the reliability and versatility of compound flaps, these maneuvers alone
should not be confused with creating distinct flap types but rather acknowledged
to be only important variations. With this understanding, this revised nomenclature
system for compound flaps is intended to be a means of standardizing communi-
cation and to facilitate research agendas on a common ground, fully realizing its
primary role still only to serve as a convenient guideline. (Plast. Reconstr. Surg. 117:
151e, 2006.)

A
systematic nomenclature for flaps was a “random” cutaneous flap. 1 Such simplicity
relatively easy endeavor during most of abruptly ceased after Milton proved that the ar-
the last century because essentially all bitrary length-to-width ratio for flap construction
known possibilities were just a variation of the was an inaccurate and now archaic principle,
and that tissue viability instead depended on the
From the Division of Plastic Surgery, The Lehigh Valley Hospital. nuances of the circulation contained within the
Received for publication May 17, 2005; revised September 4, 2005. given flap territory.2 Coincident with the subse-
Presented in part at the Inaugural Congress of the World Society
for Reconstructive Microsurgery, in Taipei, Taiwan, November
quent and ongoing thorough analyses of the
2, 2001; the 28th Annual Meeting of the Japanese Society of anatomical bases for flap vascularization, there
Reconstructive Microsurgery, in Yamanashi, Japan, November has been an exponential growth of potential flap
22, 2001; the Sixth International Course on Perforator Flaps, choices but, concomitantly, a corresponding pot-
in Taoyuan, Taiwan, October 24 through 26, 2002; and the pourri of nomenclature that frequently can be
71st Annual Scientific Meeting of the American Society of Plas- redundant, confusing, and at times even conflict-
tic Surgeons, in San Antonio, Texas, November 5, 2002. ing.
Copyright ©2006 by the American Society of Plastic Surgeons A complete and standardized classification
DOI: 10.1097/01.prs.0000219178.20541.7f schema for all types of flaps that would eliminate

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Plastic and Reconstructive Surgery • June 2006

the aforementioned dilemma may be an unreal- for compound flaps would be valuable to enhance
istic goal,3 and none certainly has yet been uni- worldwide communication in describing similar in-
versally accepted. Nakajima et al.,4 as an example novations and to further advance the reliable role
of such an attempt, divided just skin flaps into of these complex flaps not only as microsurgical
five distinct entities, whereas Nahai and Mathes tissue transfers but also possibly their more simple
proposed five fundamental types of muscles as use as local flaps when applicable. A simplified
flaps.5 Both these schema stratified their flaps nomenclature schema has been previously intro-
according to what was considered to be the most duced in this Journal,11 and will be updated to
crucial factor during flap dissection that would further clarify and standardize the terms used to
ensure flap survival (i.e., the preservation of its classify compound flaps.
vascular supply).
However, an awareness of only the source of BASIC SUBDIVISIONS OF COMPOUND
circulation to a flap often provides an incom- FLAPS
plete description. The identification of second- As stated previously, a compound flap incor-
ary characteristics is essential to create a more porates many diverse tissue components into an
accurate depiction, which is often necessary to interrelated unit. These can be partitioned into
improve the efficacy of flap dissection and more two major classes according to their most critical
effective communication of results. To rectify element, their primary means of vascularization
such an omission, Daniel and Kerrigan6 added (Fig. 1). The intense interest about this subject by
the “method of movement” in their description our Asian colleagues has led to an evolution of the
of flaps. Tolhurst7,8 was even more elaborate with original simplified categorization,14 –17 which has
his “atomic system,” but flap composition rather more closely adopted the ideas first promulgated
than the origin of the circulation was his primary by Belousov et al.18 Some differences still exist, as
focus or nucleus. Cormack and Lamberty,9,10 in each of the two subdivisions can include individ-
their anatomical system for complete flap classi- ual, or “monoflaps,” as Belousov et al.18 termed
fication, refined Tolhurst’s proposition by re- them, or multiple related flaps that they called
placing the circulation as the crucial central fac- “polyflaps.” These polyflaps in turn can be further
tor. The other subordinate characteristics used differentiated by their inherent vascular pedicle,
by them to describe any flap could be remem- which can be indigenous or surgically manipu-
bered by the pneumonic of the “6 C’s” for flap lated to conjugate these flaps into advantageous
classification. In addition to the circulation, this combinations.
included constituents (composition or tissue
type), conformation (form or shape), contiguity
(destination), construction (type of pedicle), Solitary Vascularization
and conditioning (preparation).9,10 Composite Flaps
The intent of this updated review is not to fur- From a conceptual standpoint, the simplest
ther elaborate on how to completely classify any form of compound flap is the composite flap that
flap but rather to concentrate on describing the contains en bloc multiple tissue components.19
constituents or composition of a flap, and specifi- The entire flap has a well-defined and solitary
cally only as regards the unique class of compound source of vascular supply that is intertwined within
flaps. A compound flap typically consists of multi- all parts. Thus, all the components are dependent
ple tissue components linked together in a manner on each other and must all remain intact together
that allows their simultaneous transfer and conse- to sustain overall flap viability.20,21
quently a more efficient reconstruction.11 This ap- The ubiquitous musculocutaneous and fascio-
proach obviates the need to resort otherwise to cutaneous flaps would be common examples of a
using many unrelated flaps from multiple donor composite flap, because these basically consist of
sites. Numerous variations of compound flaps have muscle or a fascial plexus, respectively, but in ad-
been sporadically introduced over the years. This dition have a skin and subcutaneous tissue paddle
also has created some confusion because minor that depends on muscle or fascial perforators for
modifications often have been given different sustenance. Intuitively, it could even be construed
names or eponyms. In reality, many of these ma- that all flaps are composite flaps, as all are also
neuvers have represented only a small change in composed of a discrete microvasculature plus con-
surgical technique, yet the basic flap composition nective tissues plus intrinsic nerves plus fat, and so
has remained unaltered.12 As Koshima has forth, in addition to their basic building blocks.
stressed,13 a straightforward nomenclature system However, this semantic technicality will hereafter

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Volume 117, Number 7 • Nomenclature for Compound Flaps

would form some type of combined flap. The two


major subtypes of combined flaps primarily differ
in the physical relationship of their component
flaps, yet are similar in that each anatomical flap
territory that is part of the combination always
retains its independent blood supply.
Conjoined Flaps
Harii et al.23,24 deserve the credit for introduc-
ing the concept of combined flaps, as they first
described a “combined myocutaneous flap and
microvascular free flap.” Their example captured
both the skin territory of the latissimus dorsi mus-
culocutaneous flap and the groin flap, which re-
mained connected together to essentially form a
bipedicled flap based at opposite ends on the tho-
racodorsal and superficial circumflex iliac vessels,
respectively.23 Either pedicle could be divided to
increase the arc of rotation or reach of the com-
bination in a caudal or cephalad direction, but an
auxiliary form of revascularization by means of
microanastomoses was then required for that ter-
ritory no longer nourished as a local pedicled flap.
Although theoretically still a single flap,
Belousov et al.18,25 called these exceedingly large
flaps that extended beyond the vascular territory
of a single vascular pedicle, not inappropriately,
“megaflaps.” In essence, these flaps are combina-
tions of at least two anatomically distinct territo-
ries, each retaining their independent vascular
supply but joined by means of some common phys-
ical boundary. The term “Siamese flap,” derived
from the congenital anomaly of the well-known
Fig. 1. Compound flaps may be subdivided into either solitary Siamese twins Chang and Eng (1811–1874),26 who
(above) or combined types (center and below) based on their pri- were born with their chests joined together, has
mary source of vascularization. There are in turn two important been often used as an apropos descriptive appel-
subtypes of combined flaps. lation for this combination.16,19,21 Because those
Siamese twins were indeed conjoined twins, the
term conjoined flap would perhaps be a more
be intentionally overlooked in this proposed politically correct synonym.
schema, as this would confuse any further at- Shibata et al.27 demonstrated another advantage
tempts at simplification. of this concept with a distal-pedicled posterior in-
Composite flaps usually are monoflaps, follow- terosseous (dorsal forearm) and lateral arm con-
ing the terminology of Belousov et al.,18 although joined flap for thin coverage of hand defects, that
sometimes at their periphery they can be partially
proved that at least a venous anastomosis for the
divided along major branches of the solitary
detached pedicle can sometimes be avoided, as the
source vessel into multiple parts that allow greater
dorsal forearm veins proved sufficient to drain the
freedom in insetting.22 Composite flaps are ade-
entire combination. Nassif et al.28 hypothesized that
quate for uncomplicated defects where the defi-
conjoined flaps do not necessarily have to be just
cits are anatomically adjacent and require essen-
cutaneous flaps, citing a combined latissimus dorsi
tially only a two-dimensional insetting.14
muscle and parascapular fasciocutaneous flap that
remained attached to each other by means of com-
Combinations of Vascularization mon musculocutaneous perforators as an example.
All other compound flaps have multiple The latter has been clinically shown to enhance the
sources of vascularization and their permutations survival of either or both components,29 presumably

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Plastic and Reconstructive Surgery • June 2006

because of a reversal of flow through the captured


perforators.30
Of course, any direct or indirect perforator
flap31 that has more than a single perforator could
theoretically also be considered to be a conjoined
flap. Indeed, each perforator has its own corre-
sponding skin territory, and yet otherwise all re-
main connected by common borders within the
flap, like the pieces of a puzzle. That portion based
on a single perforator of such a flap could still be
parceled out and transferred as a separate
monoflap. This actually has already been accom-
plished using multiple radial forearm free flaps
from a single forearm donor site,32 or by splitting
a flap into pieces that still remain pedicled to a
common source vessel, which would make this
new configuration a perforator-based chimeric
flap,33 as is discussed below.
For the sake of completeness, a cutaneous flap
with multiple perforators still intact, much like a
megaflap, would be considered a perforator-based
conjoined flap (Fig. 2). The flap originally intro-
duced by Harii et al.,23 because it is dependent on
large subfascial branches and not perforators spe-
cifically, could be called a branch-based (indepen-
dent) conjoined flap because the source vessel
branches to each territory were independent of
each other at opposite extremes of the flap. The
separate branches to the latissimus dorsi muscle
and parascapular combined flap proposed by Nas-
sif et al.,28 which could retain a common mother Fig. 2. Conjoined flaps can be further stratified into two sub-
vessel, the subscapular, would be called a branch- classes that are distinguished by their distinctly different source
based (common) conjoined flap. of vascularization; they can be either perforator-based (above) or
Chimeric Flaps branch-based (center and below). The larger caliber and often
The term “chimeric flap” was conceived origi- subfascial or axial branches of the branch-based form may have
nally to describe a combination of local flaps from completely unrelated origins from different angiosomes (the in-
the same anterolateral thigh angiosome.20 The chi- dependent type), or these branches may arise from a common
meric flap has probably been the most frequently source vessel (common type).
reported form of combined flap,17,34 –39 and use of
this term has become entrenched16,17,20,21 despite the
original attempt to name this type of combination chimeric flap would be considered a branch-based
the “conjoint” flap,11,40 which really is a more appro- type, with multiple relatively large subfascial
priate term to describe the Siamese combined flap. branches emanating from a common mother ves-
Also called polyflaps,18 the chimeric flap consists of sel. This type allows the simultaneous transfer of
multiple otherwise independent flaps that each have multiple and varied tissue components from a sin-
an independent vascular supply, but in turn all gle donor site. The subscapular system epitomizes
pedicles are linked to a larger common source this genre, where fascial (e.g., scapula, parascapu-
vessel.18,20 Because these combinations ultimately lar), muscle (e.g., serratus anterior, latissimus
have only a single source vessel, the microsurgical dorsi), and osseous (e.g., rib, scapula) flaps sup-
transfer of these combined multiple flaps can be plied by the thoracodorsal or circumflex scapular
accomplished while requiring only a single recipient branches can allow over five dozen known differ-
site, which is a major advantage (Table 1). ent flap permutations that permit near total free-
Huang et al.14 have further subdivided chi- dom in the independent insetting of each part.38
meric flaps into three subtypes, again based on As already mentioned, an intact perforator
their specific blood supply (Fig. 3). The classic flap with multiple perforators could be considered

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Table 1. Comparison of the Attributes of Compound Flap Subtypes


Conjoined Chimeric

Branch- Perforator- Branch- Perforator-


Characteristic Composite Based Based Based Based Fabricated
Circulation
Long pedicle ⫾ ⫾ – ⫹ – ⫹
Large caliber ⫾ ⫾ – ⫹ – ⫹
Single recipient site ⫹ – – ⫹ ⫹ ⫹
required
Composition
Multiple tissue types ⫹ ⫾ – ⫹ – ⫹
Independent inset of – – – ⫹ ⫹ ⫹
components
Anatomical consistency ⫹ ⫹ – ⫹ – ⫹
Conformation
Customized volume and – ⫾ ⫾ ⫹ ⫹ ⫹
contour
Contiguity
Local flap ⫹ – ⫹ ⫹ ⫹ –
Free flap ⫹ – ⫹ ⫹ ⫹ ⫹
Donor-site morbidity
Single site ⫹ – ⫹ ⫹ ⫹ –
Minimal residue ⫹ ⫾ ⫹ ⫾ ⫹ ⫾
Ease of dissection ⫹ ⫾ – ⫾ – –
⫹, positive attribute; –, negative or absent attribute.

Fig. 3. Chimeric flaps can be further stratified into three subclasses differentiated on the basis of either their intrinsic
vasculature (above) or whether they are prefabricated (below) (i.e., surgically joined together by means of a microa-
nastomosis). The fabricated component can be attached to the terminus of the source vessel to the combination
(sequential type) or to a branch indigenous within the flap (internal type).

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Plastic and Reconstructive Surgery • June 2006

a form of conjoined flap, as each perforator has its


own independent territory. If their common
boundaries are split apart, yet each part based on
its individual perforator remains attached to the
same common source vessel, these would become
instead perforator-based chimeric flaps.33 The an-
terolateral thigh flap is the prototype donor site
for this variation and has been split into smaller
flaps especially useful for head and neck recon-
struction, epitomized by the simultaneous recon-
struction of intraoral and cheek defects while
avoiding flap infolding or deepithelialization.41 As
another advantage, Sano et al.42 have split the
medial sural gastrocnemius muscle perforator
free flap into very small chimeric flaps that, when
inset together, allow coverage of large defects, but
the overall original width is narrow enough to
permit direct closure of the donor site.
Koshima et al., in their introduction to the
chimeric flap principle, prefabricated combina-
tions, attaching otherwise independent flaps to
either side branches of the main source vessel or
to its distal continuation.43 This type of fabricated
chimeric flap thus always requires a microanasto-
mosis. If the added flap is directly connected to the
distal end of the source vessel supplying the orig-
inal flap, the resulting combined flap in the pre-
vious simplified nomenclature11 was called a se-
quential flap because circulation first had to
proceed by means of a “flow-through” across the
first flap or “bridge flap” to the attached one in
sequence. In reality, in this age of perforator flaps,
Fig. 4. A supercharged flap (above) receives vascular augmen-
such a fabricated flap is better considered as a
tation from an unrelated source vessel (arrow). A turbocharged
combination of independent flaps linked to a
flap (center and below) siphons off flow from a vessel already in-
common source vessel, which by definition can
trinsic to the flap territory, here demonstrated to be directly from
only be a true chimeric flap.
a branch of the flap source vessel (arrow) as in Koshima’s mosaic
flap principle19,44 or by means of an interposed vein graft (v.g.) if
CLARIFICATION OF TECHNICAL there is a lack of vessel contiguity as Core had proposed.12
MODIFICATIONS
As inferred by the previous definitions, many
specific variations of compound flaps are in reality Supercharging and Turbocharging
just minor modifications of the basic forms. Core Semple developed a compelling analogy of
correctly pointed out that many of these are pri- supercharging and turbocharging as related to
marily technical alterations of the basic com- automotive terms.50 If an external power source is
pound flaps; if given a separate name, this only used to boost an engine’s performance, this is
serves to cause obfuscation of this concept.12 Ko- supercharging50 (e.g., the use of an unrelated dis-
shima’s “mosaic” flap is a good case in point with tant vascular source by means of an anastomosis to
which to demonstrate this omnipresent dilemma a flap to augment either inflow or outflow) (Fig.
(Fig. 4).13,44 The confusing concepts of “turbo- 4).51 The superior unipedicled transverse rectus
charging” and “supercharging” must first be de- abdominis musculocutaneous (TRAM) flap sal-
fined. Unfortunately, even these terms have pre- vaged by an anastomosis of a thoracic or upper
viously been used interchangeably, even within extremity vascular source to the contralateral deep
the same report to imply the creation of new flap or superficial inferior epigastric vessels would be
types.16,45– 49 a classic example.45– 47

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Volume 117, Number 7 • Nomenclature for Compound Flaps

In contradistinction, vehicular turbocharging compound flaps and even the subtypes of combined
relies on the engine’s own exhaust for additional flaps have also been described, which can become an
power.50 Thus, if the terminus or a branch of the overwhelming task to precisely categorize. Single do-
major pedicle to a flap were joined to another nor sites chosen as the source of a combined flap can
minor pedicle, flow to the flap (the engine) could be composed of identical (e.g., the latissimus dorsi
be siphoned away (the exhaust) to augment an and serratus anterior chimeric muscle flap56 ), or
ischemic portion (Fig. 4).51 Semple directly con- different tissue types (e.g., the subscapular-based
nected the ipsilateral and contralateral deep in- quadrifolate flap, consisting of bone, muscle, and
ferior epigastric vessels of a TRAM flap, after first fasciocutaneous flaps34). A combined flap can also
ensuring adequate retrograde pressures, specifi- be composed of a series of multiple composite flaps
cally to improve transmidline blood flow of a su- (e.g., the anterolateral and anteromedial thigh con-
perior unipedicled TRAM flap50 (i.e., he turbo- joined perforator flap44).
charged the flap). A perforator-based conjoined flap if divided
becomes a perforator-based chimeric flap, where
Mosaic Flaps the difference is more than simply “hair splitting.”
Core turbocharged the notoriously unreliable Even the components of a musculocutaneous
distal skin portion of a vertically oriented gracilis composite flap can now be separated by the te-
musculocutaneous flap by connecting what oth- dious intramuscular dissection of the musculocu-
erwise would be a perforator to a medial thigh flap taneous perforators into separate muscle and true
by means of a vein graft to a branch of the muscle’s muscle perforator flaps.15 If the latter remain at-
dominant medial circumflex femoral pedicle, be- tached to the same solitary vessel, this combina-
cause these vessels were not contiguous.52 Ko- tion would then be a chimeric flap.
shima et al.44 similarly connected the source A final example of the potential confusion and
pedicles of two adjacent thigh perforator flaps ambiguity still possible is represented by a case re-
directly to each other to augment flow but called port of a caudal-pedicled local latissimus dorsi–
this variation a “mosaic” flap (Fig. 4). Both Core’s groin flap [a classic conjoined flap (branch-based)]
salvage maneuver and Koshima et al.’s mosaic flap used to cover a large thoracoabdominal defect
really represent only the turbocharging of what where the thoracodorsal pedicle was revascularized
are conjoined flaps. by means of a flow-through radial forearm free flap.57
Because this was surgically prefabricated before in-
setting by means of a microanastomosis, this com-
Chain-Link Flaps
bination then becomes a fabricated (sequential
The sequential fabrication of a chimeric flap type) chimeric flap according to this revised schema.
by the microsurgical attachment of another flap
that is perfused by a vascular flow-through across DISCUSSION
the original flap has been called a “piggybacked The touted advantage of compound flaps as a
flap.”53,54 Because in this fashion multiple piggy- group is their ability to simultaneously provide
backed flaps can be linked together sequentially multiple tissue types as building blocks of virtually
much as links on a chain, these have also been unlimited size to fill any volume deficit, restore any
called “chain-link” flaps55 but are no different absent underlying framework, and allow immedi-
from fabricated (sequential) chimeric flaps. Ko- ate coverage (Table 1).11,14 The ultimate shape and
shima’s “chain-circle” flaps piggybacked a second contour can be independently customized and
flap to the terminus of a flow-through of the first, then inset with impunity, especially with the chi-
but also attached the vascular terminus of the meric type of combined flap.43 Ideally, all neces-
pedicle of the second flap back to a branch of the sary components can be obtained from a single
original flow-through, which could really be con- donor site that will then be closed primarily to
sidered to be only a form of turbocharging.16,43 It minimize overall morbidity. If multiple indepen-
is no wonder these terms can be confusing, but dent flaps arise from a single mother major source
careful scrutiny as done here reveals that these are vessel, a compound free flap will require only a
all only technical modifications of defined com- single recipient site to revascularize the entire
pound flaps, and not new entities. complex, a major advantage when a paucity of
recipient vessels can otherwise be a significant lim-
Hybrid Compound Flaps iting factor. Intentional inclusion of a second
Despite the best efforts to fully clarify this issue, small yet independent flap as part of either a
permutations within and between the subdivisions of branch-based or perforator-based chimeric free

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Plastic and Reconstructive Surgery • June 2006

flap can be specifically designed to protect or re- nuances of the terminology used to describe this
lieve tension at a tenuous recipient site38 or serve important concept.
as a monitoring flap.58
Geoffrey G. Hallock, M.D.
However, there must always be a disclaimer. Ba- 1230 South Cedar Crest Boulevard, Suite 306
sic principles in flap selection should always be fol- Allentown, Pa. 18103
lowed. If a single flap is sufficient,11,18 the temptation pbhallock@cs.com
to choose any compound flap requires that there be
unquestioned advantages.11 As previously reported ACKNOWLEDGMENTS
in our experience with over 1500 flaps over the past David C. Rice, B.S., physician extender, Sacred
25 years, only 14 percent of free flaps and fewer than Heart Hospital, Allentown, Pennsylvania, assisted with
5 percent of all flaps that were used (excluding rou- all microsurgery advancements, and Carol Varma, med-
tine musculocutaneous and fasciocutaneous com- ical illustrator, The Lehigh Valley Hospital, Allentown,
posite flaps) were compound flaps,11 proving that by Pennsylvania, provided the schematics.
far this concept has a minority role. The restricted
indications for compound flaps were directly related
to disadvantages distinct for each subtype. Compos- REFERENCES
ite flaps are often bulky, and immediate thinning 1. Pearl, R. M., and Johnson, D. The vascular supply to the skin:
An anatomical and physiological reappraisal: Part II. Ann.
could jeopardize their overall vitality. Their individ- Plast. Surg. 11: 196, 1983.
ual parts for the same reason cannot be indepen- 2. Milton, S. H. Pedicled skin-flaps: The fallacy of the length:
dently inset, which can become cumbersome. Inde- width ratio. Br. J. Surg. 57: 502, 1970.
pendent branch-based conjoined flaps, unless 3. Hallock, G. G. The complete classification of flaps. Microsur-
transposed as a local bipedicled flap,59 require a gery 24: 157, 2004.
4. Nakajima, H., Fujino, T., and Adachi, S. A new concept of
recipient vessel conveniently located at the end of vascular supply to the skin and classification of skin flaps
the flap’s reach to provide the mandatory auxiliary according to their vascularization. Ann. Plast. Surg. 16: 1,
revascularization. This could become a logistical 1986.
nightmare in flap planning. Any perforator-based 5. Mathes, S. J., and Nahai, F. Classification of the vascular
conjoined or chimeric flap requires a more tedious anatomy of muscles: Experimental and clinical correlation.
Plast. Reconstr. Surg. 67: 177, 1981.
dissection, just like any muscle perforator flap.14,15 6. Daniel, R. K., and Kerrigan, C. L. Principles and physiology
Anatomical anomalies of perforator flaps in partic- of skin flap surgery. In J. G. McCarthy (Ed.), Plastic Surgery ,
ular and chimeric flaps in general are not infre- Vol. 1. Philadelphia: Saunders, 1990. Pp. 275–328.
quent, which could require the inconvenience of 7. Tolhurst, D. E. Fasciocutaneous flaps and their use in re-
additional microanastomoses or even complete constructive surgery. Perspect. Plast. Surg. 4: 129, 1990.
8. Tolhurst, D. E. A comprehensive classification of flaps: The
abandonment of that donor site.38,60,61 Postoperative atomic system. Plast. Reconstr. Surg. 80: 608, 1987.
monitoring can also be problematic, as one flap of 9. Lamberty, B. G. H., and Healy, C. Flaps: Physiology, princi-
a combination can remain totally viable while an- ples of design, and pitfalls. In M. Cohen (Ed.), Mastery of
other withers away undetected. A good example is a Plastic and Reconstructive Surgery. Boston: Little, Brown, 1994.
case where loss of only the more distal flap in a Pp. 56–70.
10. Cormack, G. C., and Lamberty, B. G. H.. The anatomical
fabricated chimeric flap was reported, presumably basis for fasciocutaneous flaps. In G. G. Hallock (Ed.), Fas-
because of the increased thrombogenicity caused by ciocutaneous Flaps. Cambridge, Mass.: Blackwell Scientific,
the more proximal anastomotic site.53 1992. Pp. 13–24.
11. Hallock, G. G. Simplified nomenclature for compound flaps.
Plast. Reconstr. Surg. 105: 1465, 2000.
12. Core, G. B. Re: Extended anterior thigh flaps for repair of
CONCLUSIONS massive cervical defects involving pharyngoesophagus and
Compound flaps, just because of their greater skin: An introduction to the “mosaic” flap principle (Letter).
innate complexity, will have unique complications Ann. Plast. Surg. 33: 461, 1994.
that must be anticipated and circumvented. To 13. Koshima, I. Re: Extended anterior thigh flaps for repair of
maximize their potential and justify their niche in massive cervical defects involving pharyngoesophagus and
skin: An introduction to the “mosaic” flap principle (Reply).
the reconstructive hierarchy,62 compound flaps Ann. Plast. Surg. 33: 462, 1994.
must always be chosen prudently and only when 14. Huang, W. C., Chen, H. C., Wei, F. C., Cheng, M. H., and
appropriate. The similarities yet inherent differ- Schnur, D. P. Chimeric flap in clinical use. Clin. Plast. Surg.
ences in the subtypes of compound flaps have 30: 457, 2003.
been highlighted in this updated review. This re- 15. Wei, F. C., Jain, V., Suominen, S., and Chen, H. C. Confusion
among perforator flaps: What is a true perforator flap? Plast.
vised classification schema has itself undergone a Reconstr. Surg. 107: 874, 2001.
significant evolution as our knowledge of flaps has 16. Koshima, I. A new classification of free combined or con-
advanced but possibly has further clarified the nected tissue transfers: Introduction to the concept of

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bridge, siamese, chimeric, mosaic, and chain-circle flaps. limb, using combined ascending scapular and latissimus
Acta Med. Okayama 55: 329, 2001. dorsi flaps. J. Reconstr. Microsurg. 11: 407, 1995.
17. Wei, F. C., Celik, N., and Jeng, S. F. Application of “simplified 37. Chen, H. C., El-Gammal, T. A., Chen, H. H., Wei, F. C., Lin,
nomenclature for compound flaps” to the anterolateral C. H., and Tang, Y. B. Economy of donor site incisions:
thigh flap. Plast. Reconstr. Surg. 115: 1051, 2005. Multiple free flaps of the subscapular family for extensive
18. Belousov, A. E., Kishemasov, D. S., Kochish, A. Y., and Pin- extremity wounds and bilateral foot defects. Ann. Plast. Surg.
chuk, V. D. A new classification of vascularized flaps in plastic 41: 28, 1998.
and reconstructive surgery. Ann. Plast. Surg. 31: 47, 1993. 38. Hallock, G. G. Permutations of combined free flaps using the
19. Cormack, G. C., and Lamberty, B. G. H. Alternative flap subscapular system. J. Reconstr. Microsurg. 13: 47, 1997.
nomenclature and classification. In The Arterial Anatomy of 39. Fairbanks, G. A., and Hallock, G. G. Facial reconstruction
Skin Flaps, 2nd Ed. Edinburgh: Churchill Livingstone, 1994. using a combined flap of the subscapular axis simultaneously
Pp. 514–522. including separate medial and lateral scapular vascularized
20. Hallock, G. G. Simultaneous transposition of anterior thigh bone grafts. Ann. Plast. Surg. 49: 104, 2002.
muscle and fascia flaps: An introduction to the chimera flap 40. Hallock, G. G. The conjoint medial circumflex femoral per-
principle. Ann. Plast. Surg. 27: 126, 1991. forator and gracilis muscle free flap. Plast. Reconstr. Surg. 113:
21. Hallock, G. G. The chimera flap principle: Conjoint flaps. In 339, 2004.
G. G. Hallock (Ed.), Fasciocutaneous Flaps. Cambridge, Mass.: 41. Huang, W. C., Chen, H. C., Jain, V., et al. Reconstruction of
Blackwell Scientific, 1992. Pp. 172–180. through-and-through cheek defects involving the oral com-
22. Chowdary, R. P. Use of temporoparietal fascia free flap in missure, using chimeric flaps from the thigh lateral femoral
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23. Harii, K., Iwaya, T., and Kawaguchi, N. Combination myo- 42. Sano, K., Hallock, G. G., Hamazaki, M., and Daicyo, Y. The
cutaneous flap and microvascular free flap. Plast. Reconstr. perforator-based conjoint (chimeric) medial sural (medial
Surg. 68: 700, 1981. gastrocnemius) free flap. Ann. Plast. Surg. 53: 588, 2004.
24. Harii, K. Microvascular free flaps for skin coverage: Indica- 43. Koshima, I., Yamamoto, H., Hosoda, M., Moriguchi, T.,
tions and selections of donor sites. Clin. Plast. Surg. 10: 37, Orita, Y., and Nagayama, H. Free combined composite flaps
1983. using the lateral circumflex femoral system for repair of
25. Belousov, A. E., Kishemasov, D. S., Kochish, A. Y., and Pin- massive defects of the head and neck regions: An introduc-
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chuk, V. D. Vascularized megaflaps. Ann. Plast. Surg. 31: 54,
411, 1993.
1993.
44. Koshima, I., Yamamoto, Y., Moriguchi, T., and Orita, Y. Ex-
26. Webster’s New World Dictionary of the American Language. New
tended anterior thigh flaps for repair of massive cervical
York: The World Publishing Co., 1960. P. 1353.
defects involving pharyngoesophagus and skin: An introduc-
27. Shibata, M., Hatano, Y., Iwabuchi, Y., and Matsuzaki, H.
tion to the “mosaic” flap principle. Ann. Plast. Surg. 32: 321,
Combined dorsal forearm and lateral arm flap. Plast. Reconstr.
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Surg. 96: 1423, 1995.
45. Muhlbauer, W., Herndl, E., Schmidt, A., and Henckel-v.-
28. Nassif, T. M., Vidal, L., Bovet, J. L., and Baudet, J. The
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vascular anastomoses of the TRAM or VRAM flap in breast
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reconstruction: The turbo-charged flap. Eur. J. Plast. Surg. 14:
29. Hallock, G. G. The combined parascapular fasciocutaneous 17, 1991.
and latissimus dorsi muscle “conjoined” free flap. (in press). 46. Takayanagi, S., and Ohtsuka, M. Extended transverse rectus
30. Yazar, S., Çetinkale, O. Senel, O., et al. An experimental study abdominis musculocutaneous flap. Plast. Reconstr. Surg. 83:
of skin flap associated with muscle: Is muscle nourishment 1057, 1989.
possible through the musculocutaneous perforators? Ann. 47. Harashina, T., Sone, K., Inoue, T., Fukuzumi, S., and Eno-
Plast. Surg. 45: 500, 2000. moto, K. Augmentation of circulation of pedicled transverse
31. Hallock, G. G. Direct and indirect perforator flaps: The rectus abdominis musculocutaneous flaps by microvascular
history and the controversy. Plast. Reconstr. Surg. 111: 855, surgery. Br. J. Plast. Surg. 40: 367, 1987.
2003. 48. Yamamoto, Y., Nohira, K., Shintomi, Y., Sugihara, T., and
32. Hallock, G. G. Simultaneous bilateral foot reconstruction Ohura, T. “Turbo charging” the vertical rectus abdominis
using a single radial forearm flap. Plast. Reconstr. Surg. 80: 836, myocutaneous (turbo-VRAM) flap for reconstruction of ex-
1987. tensive chest wall defects. Br. J. Plast. Surg. 47: 103, 1994.
33. Tsai, F. C., Yang, J. Y., Mardini, S., Chuang, S. S., and Wei, 49. Pernia, L. R., Miller, H. L., Saltz, R., and Vasconez, L. O.
F. C. Free split-cutaneous perforator flaps procured using a “Supercharging” the rectus abdominis muscle to provide a
three-dimensional harvest technique for the reconstruction single flap for cover of large mediastinal wound defects. Br. J.
of postburn contracture defects. Plast. Reconstr. Surg. 113: Plast. Surg. 44:243, 1991.
185, 2004. 50. Semple, J. L. Retrograde microvascular augmentation (tur-
34. Bakhach, J., Peres, J. M., Scalise, A., Martin, D., and Baudet, bocharging) of a single-pedicle TRAM flap through a deep
J. The quadrifoliate flap: A combination of scapular, paras- inferior epigastric arterial and venous loop. Plast. Reconstr.
capular, latissimus dorsi, and scapula bone flaps. Br. J. Plast. Surg. 93: 109, 1994.
Surg. 49: 477, 1996. 51. Civelek, B., Kargi, E., Akoz, T., and Sensoz, O. Turbocharge
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sian, A. R. Reconstruction of a complex defect of the hand 52. Core, G. B., Weimar, R., and Meland, N. B. The turbo gracilis
with two distinct segments of the scapula and a scapular free flap. J. Reconstr. Microsurg. 8: 267, 1992.
fascial flap transferred as a single transplant. Plast. Reconstr. 53. Wei, F. C., Demirkan, F., Chen, H. C., and Chen, I. H. Double
Surg. 90: 687, 1992. free flaps in reconstruction of extensive composite mandib-
36. Sawaizumi, M., Maruyama, Y., and Kawaguchi, N. Vertical ular defects in head and neck cancer. Plast. Reconstr. Surg.
double flap design for repair of wide defects of the lower 103: 39, 1999.

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54. Hallock, G. G. Partial failure of a free flap salvaged by using 59. Katsaros, J., Gilbert, D., and Russell, R. The use of a combined
the surviving portion as a “bridge” flap for revascularizing a latissimus dorsi-groin flap as a direct flap for reconstruction of
second free flap. Plast. Reconstr. Surg. 100: 981, 1997. the upper extremity. Br. J. Plast. Surg. 36: 67, 1983.
55. Chen, H. C., Tang, Y. B., and Noordhoff, M. S. Reconstruction 60. Sasaki, K., Nozaki, M., Nakazawa, H., Kikuchi, Y., and Huang,
of the entire esophagus with “chain-flaps” in a patient with T. Reconstruction of a large abdominal wall defect using
severe corrosive injury. Plast. Reconstr. Surg. 84: 980, 1989. combined free tensor fasciae latae musculocutaneous flap
56. Hallock, G. G. Conjoint muscle free flap for obliteration of an and anterolateral thigh flap. Plast. Reconstr. Surg. 102: 2244,
upper thoracic empyema cavity. Can. J. Plast. Surg. 11: 216, 2003. 1998.
57. Chiang, Y. C., Chen, F. C., Hsieh, M. J., and Wei, F. C. 61. Colen, L. B. The anatomy of the lower serratus anterior
Reconstruction of a large thoracoabdominal wall defect with muscle: A fresh cadaver study (Discussion). Plast. Reconstr.
a flow-through forearm flap and a latissimus dorsi-groin flap. Surg. 95: 98, 1995.
Plast. Reconstr. Surg. 100: 1240, 1997. 62. Gottlieb, L. J., and Krieger, L. M. From the reconstructive
58. Hallock, G. G. Free flap monitoring using a chimeric sentinel ladder to the reconstructive elevator. Plast. Reconstr. Surg. 93:
muscle perforator flap. J. Reconstr. Microsurg. 21: 351, 2005. 1503, 1994.

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