Psychological

INFORM ATION - Mood Swings

- Depression
The exact name of Huntington's Disease is
- Irritability
HTT gene, Chromosome 4.
Com plicat ion s
The protein coded for by gene is the
Unfortunately, Huntington's disease has many
HUNTINGTON'S
Huntington protein

Sym pt om s
complications. One of them is lack of DISEASE
motivation which can lead to depression and
Cognitive make even the simplest tasks difficult.
Pneumonia and heart disease are also two of
- Amnesia
the most common causes of death for patients
- Delusion
with Huntington's disease. Not only that but
- Difficulty thinking/understanding
Huntington disease patients are at a higher risk
- Lack of concentration
for choking, gastrointestinal diseases, and
Muscular suicide compared to people without the disease.
Shorter life expectancies are also common for
- Involuntary movement
patients diagnosed with Huntington's disease.
- Problems with coordination
- Muscle spasms Tr eat m en t
Behavioral There is no treatment for Huntington's Disease
but there are ways to prevent it and
- Fidgeting
medications for the symptoms. To prevent this
- Lack of restraint
disease there is genetic testing, prenatal testing,
- Compulsiveness
and pre-implantation genetic diagnosis. There
are medications available for symptoms such as,
abnormal movement, behaviors, and
depression.

Contact us for information.

Research Out look
Although we are far from finding a cure for
Huntington's disease, researchers remain (202) 555-0128
hopeful that there will eventually be a cure in YOUR HEALTH
the future. As of now, there has been testing to
reduce the toxic form of the Huntington protein 7691 Rose Dr. IS OUR PRIORITY
by using a blocker to interfere with the gene in Norwood, MA 02062
mice. However, it is difficult to adjust the few
medications that are successful to humans.
stayinghealthy@medicalcare.com
 HUNTINGTON'S
CHROM OSOM E
Pedigree
This is a pedigree of a family that has a
history of Huntington's disease. The
disease is autosomal dominant, so there
are no carriers. Either someone has it or
they don't.
W ebsit es For M ore
Informat ion
- Genetics Home Reference-
https://ghr.nlm.nih.gov/conditi
on/huntington-disease
- MedlinePlus-
https://medlineplus.gov/ency/artic
le/000770.htm
- National Institute of Neurological
Disorders and Stroke-
https://www.ninds.nih.gov/Disorders
/All-Disorders/Huntingtons-Diseas
e-Information-Page
- National Organization for Rare
Disorders-
https://rarediseases.org/for
-patients-and-families/help-access-
medications/patient-assistanc e-programs-2/
Inherit ance
Huntington's Disease is a single gene
mutation and is autosomal dominant.
This means one copy of the altered gene
in each cell is sufficient to cause the
disorder. It is usually inherited from an
affected parent.
W orks Cit ed
- GARD. "Huntington Disease." Genetic and Rare Diseases
Information Center (GARD) ? an NCATS Program |
Providing Information About Rare or Genetic Diseases,
Genetic and Rare Diseases Information Center, 8 July
2015, rarediseases.info.nih.gov/diseases/6677
/huntington-disease.
- Mayo Clinic. "Huntington's Disease - Symptoms and
Causes." Mayo Clinic, Mayo Foundation for Medical
Education and Research, 16 May 2018,
www.mayoclinic.org/diseases-conditions/hunti
ngtons-disease/symptoms-causes/syc-20356117.
- YourGenome. "What is Huntington's Disease?"
Yourgenome.org | Helping You Discover More About DNA,
Genes and Genomes, and the Implications for Our Health
and Society, Wellcome Genome Campus, 17 Nov. 2014,
www.yourgenome.org/facts/what-is-huntingtons-disease
- Genetics Home Reference. "Huntington Disease."
Genetics Home Reference,
ghr.nlm.nih.gov/condition/huntington-disease.
Int erest ing Fact s
1. Woody Guthrie, a famous singer
known for American folk music,
had Huntington's disease.
2. Huntington's disease occurs in
about 1 in 15,000 people across
the globe.
Woody Guthrie