Choosing the Right Masterflex® Tubing Formulation

Application suitability†

Pump tubing Meets Gas

Pressure
Advantages Sterilization

solvents

Vacuum
Alkalies
Organic

Viscous
formulation classifications permeability

Sterile
fluids

Silicone
(platinum-cured)
96410-, 96510-series
fluids
Acids
Excellent biocompatibility. USP Class V Extractables
No leachable additives, DOP, or plasticizers; N/R N/R N/R F G F E Exceeds Class VI Implant
phthalate and latex-free; odorless and nontoxic, European Pharmacopoeia (EP 3.1.9) CO2: 20,132
Sterilize by EtO,
fungus-resistant. FDA 21 CFR 177.2600; FDA 21 CFR 210 H2: 6579
autoclave, or
No taste imparted to transported fluids. and 211; Exceeds 3A sanitary cGMPs; O2: 7961
Temperature range: gamma irradiation.
Weather, ozone, corona, and radiation resistant. REACH (non-DEHP) compliant N2: 2763
Minimal tendency to take a set. Static: –50 to 230°C (–58 to 446°F) RoHS compliant
Translucent, clear to light amber. Dynamic (pumping): –40 to 100°C ADCF compliant
(–40 to 212°F)

Silicone
(peroxide-cured)
96400-, 96406-series
Excellent biocompatibility.
N/R N/R N/R F G F E USP Class VI
No additives, plasticizers or DOP; odorless
European Pharmacopoeia (EP 3.1.9)
and nontoxic, fungus-resistant. CO2: 20,132
FDA 21 CFR 177.2600
No taste imparted to transported fluids. H2: 6579 Sterilize by EtO or
Exceeds 3A sanitary standards
Weather, ozone, corona, and O2: 7961 autoclave.
Temperature range: REACH (non-DEHP) compliant
radiation resistant. N2: 2763
Static: –50 to 230°C (–58 to 446°F) RoHS compliant
Minimal tendency to take a set.
Dynamic (pumping): –40 to 100°C ADCF compliant
Translucent, clear to light amber.
(–40 to 212°F)

BioPharm Silicone Ultra-smooth inner surface minimizes particle

(platinum-cured)
96420-, 96421-series
entrapment. N/R N/R N/R F G F E USP Class VI
Lower absorption; excellent biocompatibility;
European Pharmacopoeia (EP 3.1.9) CO2: 25,147
no leachable additive, DOP, or plasticizers. Sterilize by EtO,
FDA 21 CFR 177.2600 H2: —
Very low extractables. autoclave, or
Exceeds 3A sanitary standards O2: 4715
Odorless and nontoxic, fungus-resistant. Temperature range: gamma irradiation.
REACH (non-DEHP) compliant N2: 2284
No taste imparted to transported fluids. Static: –60 to 232°C (–75 to 450°F) RoHS compliant
Weather, ozone, corona, and radiation resistant. Dynamic (pumping): –40 to 100°C
Translucent, clear to light amber. (–40 to 212°F)

BioPharm Plus
Silicone Similar to BioPharm Silicone, plus:
(platinum-cured) Longest life of any silicone pump tubing. N/R N/R N/R F G F E USP Class VI
Lower spallation than regular silicone. European Pharmacopoeia (EP 3.1.9) CO2: 25,147
96440-, 96441-series Sterilize by EtO,
Enhanced pressure capability. FDA 21 CFR 177.2600 H2: —
autoclave, or
Fungus-resistant. Exceeds 3A sanitary standards O2: 4715
gamma irradiation.
Nontoxic, no leachable plasticizers. Temperature range: REACH (non-DEHP) compliant N2: 2284
Lower gas permeability than other silicones. Static: –60 to 232°C (–75 to 450°F) RoHS compliant
Translucent, clear to light amber. Dynamic (pumping): –40 to 100°C
(–40 to 212°F)

Biocompatible.
Puri-Flex™ Heat sealable and weldable.
Long pump life when compared to silicone G G N/R G G E E USP Class VI
Sterilize by EtO,
96419-series or other TPE tubings. FDA 21 CFR 177.2600 and CO2: 1200
autoclave up to
Low spallation when compared to silicone 177.1810 H2: —
135°C (275°F),
or some other TPE tubings. REACH (non-DEHP) compliant O2: 200
Temperature range: gamma irradiation
Very low protein binding. RoHS compliant N2: 80
Static: –50 to 135°C (–58 to 275°F) up to 4.5 Mrad.
Cost effective. ADCF compliant
No halogens or phthalates. Dynamic (pumping): –30 to 100°C
Translucent, clear to light white. (–22 to 212°F)

C-Flex®
Physical properties similar to silicone G G N/R F G F E
USP Class VI
06424-series with chemical compatibility of Tygon®. CO2: —
European Pharmacopoeia (EP 3.2.9) Sterilize by EtO,
Inexpensive. H2: —
REACH (non-DEHP) compliant autoclave, or
Biocompatible. O2: 150
Temperature range: RoHS compliant gamma irradiation.
Heat sealable and weldable. N2: —
Static: –45 to 121°C (–50 to 250°F) ADCF compliant
Opaque, white.
Dynamic (pumping): –40 to 100°C
(–40 to 212°F)

C-Flex® ULTRA
Physical properties similar to silicone G G N/R F G F E Sterilize by gamma
with chemical compatibility of Tygon®. USP Class VI
06434-series CO2: 2.1 irradiation or one
Biocompatible. European Pharmacopoeia (EP 3.2.9)
H2: — cycle of autoclave
Heat sealable and weldable. REACH (non-DEHP) compliant
O2: 1.1 at 121°C (250°F),
Longer pump life and lower spallation Temperature range: RoHS compliant
N2: 3.4 1 bar (15 psi) for
than C-Flex. Static: –45 to 121°C (–50 to 250°F) ADCF compliant
30 minutes.
Translucent. Dynamic (pumping): –40 to 100°C
(–40 to 212°F)
†E = Excellent, G = Good, F = Fair, P = Poor, N/R = not recommended

US Toll-free: 1-800-323-4340 • Outside the US: 1-847-549-7600 • www.coleparmer.com

1
Canada 1-800-363-5900 • India 1-800-266-1244 • UK 0500-345-3000 4248
 Choosing the Right Masterflex® Tubing Formulation (continued)
Application suitability†
Pump tubing Meets Gas

Pressure
solvents
Advantages Sterilization

Vacuum
Alkalies
Organic

Viscous
formulation classifications permeability

Sterile
fluids

fluids
Acids
Great for tissue and cell
PharMed® BPT work—nontoxic and nonhemolytic.
Long service life (up to 10,000 hrs); G G N/R G G E E USP Class VI
06508-series reduces tubing costs and pump downtime. European Pharmacopoeia (EP 3.2.9) CO2: 1200 Sterilize by EtO,
Opaque to UV and visible light to protect FDA 21 CFR 177.2600 H2: — autoclave, or
light-sensitive fluids. NSF-51 O2: 200 gamma irradiation
Low gas permeability. Temperature range: REACH (non-DEHP) compliant N2: 80 up to 2.5 Mrad.
High-pressure 10.3 bar (150 psi) version Static: –51 to 132°C (–60 to 270°F) RoHS compliant
available. Dynamic (pumping): –20 to 100°C
Opaque, beige (–4 to 212°F)

Solve-Flex® Excellent chemical resistance, especially

with solvents. E E E F G E E
96446-series Chemically inert.
Low spallation. Sterilize by EtO.
USP Class VI —
Nontoxic.
Low coefficient of friction. Temperature range:
Fluoropolymer-lined tubing. Static: –51 to 132°C (–60 to 270°F)
Opaque, white. Dynamic (pumping): –20 to 100°C
(–4 to 212°F)

GORE® STA-PURE®
pump tubing N/R N/R N/R E G G E USP Class VI
Unique composite structure adds strength and
Series PCS (96211-) USP <87>
flex durability. Sterilize by
USP Physicochemical Tests
Greater security against rupture up to 100 psig*. — autoclave or SIP
Compliant with restricted
Consistent flow rate over long duration of use. (steam in place).
substances per REACH and RoHS
Withstands rigors of CIP/SIP processing. Temperature range: No raw materials of animal origin
Contact Cole-Parmer

GORE® STA-PURE®
pump tubing E E E E G G E USP Class VI
Unique composite structure adds strength and
Series PFL (96212-) USP <87>
flex durability. Sterilize by
USP Physicochemical Tests
Greater chemical resistance than Series PCS. — autoclave or SIP
Compliant with restricted
Stable flow rates achievable to 60 psig*. (steam in place).
substances per REACH and RoHS
Withstands rigors of CIP/SIP processing. Temperature range: No raw materials of animal origin
Contact Cole-Parmer

PharmaPure® Nontoxic and nonhemolytic

(similar to PharMed® BPT); biocompatible. G G N/R G G E E
USP Class VI
06435-series Long life even under pressure; up to CO2: 1200 Sterilize by EtO,
FDA 21 CFR 177.2600
1000 hours at 2.7 bar (40 psi). H2: — autoclave or
European Pharmacopoeia (EP 3.2.9)
Very low spallation—protects fluid purity. O2: 200 gamma irradiation
Temperature range: REACH (non-DEHP) compliant
Low extractables. N2: 80 up to 2.5 Mrad.
Static: –51 to 132°C (–60 to 270°F) RoHS Compliant
Low gas permeability.
Opaque, off-white. Dynamic (pumping): –20 to 100°C
(–4 to 212°F)

Chem-Durance® Bio
Excellent chemical resistance. E E G E E E E
Excellent life and durability under pressure.
06442-series USP Class VI CO2: 745
Low spallation. Sterilize by EtO,
FDA 21 CFR 177.2600 H2: —
Plasticizer-free inner liner. autoclave or
REACH (non-DEHP) compliant O2: 200
High dielectric constant. Temperature range: gamma irradiation.
RoHS Compliant N2: 80
Excellent biocompatibility. Static: –60 to 74°C (–71 to 165°F)
Opaque, beige. Dynamic (pumping): 0 to 40°C
(32 to 104°F)

PTFE Chemically inert.

Excellent chemical resistance. E E E G G E G
Will not leach into or absorb out of fluid being
77390-series USP Class VI CO2: 6.8
pumped.
REACH (non-DEHP) compliant H2: — Sterilize by EtO or
Extremely low gas permeability.
RoHS compliant O2: — autoclave.
Nontoxic. Temperature range: ADCF compliant N2: 1.0
Virtually nonporous. Static: –240 to 260°C (–400 to 500°F)
Low coefficient of friction. Dynamic (pumping): –40 to 150°C
Translucent, white. (–40 to 302°F)
†E = Excellent, G = Good, F = Fair, P = Poor, N/R = not recommended *Actual performance depends on the specific application conditions.

US Toll-free: 1-800-323-4340 • Outside the US: 1-847-549-7600 • www.coleparmer.com

2
Canada 1-800-363-5900 • India 1-800-266-1244 • UK 0500-345-3000 4248
 Choosing the Right Masterflex® Tubing Formulation (continued)
Application suitability†
Pump tubing Meets Gas

Pressure
solvents

Vacuum
Advantages Sterilization

Alkalies
Organic

Viscous
formulation classifications permeability

Sterile
fluids

fluids
Acids
Longest life of all Tygon® peristaltic tubing.
Tygon® E-LFL Clear for easy flow monitoring. USP Class VI
G G N/R G G E G
Broad chemical resistance. European Pharmacopia (EP 3.2.9)
CO2: 563
06440-series Nonaging, nonoxidizing. FDA 21 CFR 175.300
H2: —
Sterilize by EtO or
Low gas permeability. EU Food autoclave.
Temperature range: O2: 124
Smooth bore. REACH (non-DEHP) compliant
Static: –46 to 74°C (–51 to 165°F) N2: 67
Good for viscous fluids. RoHS compliant
High dielectric constant. Dynamic (pumping): 0 to 40°C ADCF compliant
Transparent, clear. (32 to 104°F)

Tygon® E-Food Designed especially for handling food products.

(B-44-4X) Bore is extremely smooth (better than FDA 21 CFR 175.300
G G N/R G G E F
most stainless steels) EU Food
CO2: 270
06418-series Nontoxic, will not affect taste or odor, and clear for NSF-51
H2: 97 Sterilize by EtO or
CIP and flow verification. REACH (non-DEHP) compliant
Temperature range: O2: 60 autoclave.
Excellent nonwetting properties permit flush RoHS compliant
Static: –36 to 74°C (–32 to 165°F) N2: 30
cleaning and complete drainage. ADCF compliant
High dielectric constant. Dynamic (pumping): 0 to 40°C Meets 3A sanitary standards
Transparent, clear. (32 to 104°F)

Tygon® E-Lab Inexpensive tubing for general laboratory

(E-3603) applications. USP Class VI
G G N/R G G E P
Clear for easy flow monitoring. FDA 21 CFR 175.300
CO2: 360
06509-series Handles virtually all inorganic chemicals. EU Food
H2: 97 Sterilize by EtO or
Nonaging, nonoxidizing. NSF-51
Temperature range: O2: 80 autoclave.
Low gas permeability. REACH (non-DEHP) compliant
Static: –46 to 74°C (–51 to 165°F) N2: 40
Good for viscous fluids. RoHS compliant
High dielectric constant. Dynamic (pumping): 0 to 40°C ADCF compliant
Transparent, clear. (32 to 104°F)

Tygon® Chemical Best chemical resistance of

(2001) any Tygon® formulation.
E E G G G E G FDA 21 CFR 175.300
Compatible with many polar solvents.
REACH (non-DEHP) compliant CO2: 114 Sterilize by EtO,
06475-series Plasticizer-free.
H2: — autoclave, or
Clear for easy flow monitoring. RoHS compliant
Temperature range: ADCF compliant O2: 19 gamma irradiation.
Low extractability.
Static: –77 to 57°C (–108 to 135°F) N2: 9
Low gas permeability.
High dielectric constant. Dynamic (pumping): 0 to 40°C
Transparent, clear. (32 to 104°F)

Tygon® Fuel & Specially formulated to transport hydrocarbons,

Lubricant (F-4040-A)
06401-series
petroleum products, and distillates. G G N/R G G E P
Suitable for gasoline, kerosene, heating oils, CO2: 100
cutting fluids, and glycol-based coolants.
REACH (non-DEHP) compliant
H2: 97 Sterilization is not
RoHS compliant
Minimum extractability. Temperature range: O2: 22 recommended.
ADCF compliant
Low gas permeability. Static: –37 to 74°C (–35 to 165°F) N2: 12
High dielectric constant. Dynamic (pumping): 0 to 40°C
Transparent, yellow. (32 to 104°F)

Norprene® Best choice for vacuum/pressure applications.

(A 60 G) Offers longest pump tubing life.
G G N/R E E E N/R
Heat, ambient ozone resistant.
CO2: 1200
06404-series Good resistance to acids/alkalies. NSF-51
H2: —
Sterilize by EtO,
Black color hides dirt and dust. REACH (non-DEHP) compliant autoclave, or
Temperature range: O2: 200
Heat sealable, nonaging, and nonoxidizing. RoHS compliant gamma irradiation.
Static: –59 to 132°C (–60 to 270°F) N2: 80
High dielectric constant.
High-pressure version available. Dynamic (pumping): –20 to 100°C
Opaque, black. (–4 to 212°F)

Norprene® Food Similar to Norprene® but with FDA approval.

(A 60 F) Excellent for food/dairy applications. G G N/R E E E G
FDA 21 CFR 177.2600
Longest life, good flow consistency. CO2: 1200
06402-series Heat and ozone resistant.
NSF-51
H2: —
Sterilize by EtO,
REACH (non-DEHP) compliant autoclave, or
Good resistance to acids/alkalies. Temperature range: O2: 200
RoHS compliant gamma irradiation.
Heat sealable, nonaging, and nonoxidizing. Static: –59 to 132°C (–60 to 270°F) N2: 80
High dielectric constant. Dynamic (pumping): –20 to 100°C
Opaque, beige. (–4 to 212°F)
Variable—test

Viton®
before using

Perfect for food and lab applications

E E G G G F
where FDA compliance is required.
CO2: 76 to 79
96412-series Excellent chemical resistance.
FDA 21 CFR 177.2600 H2: — Sterilization is not
Resistant to corrosives, solvents, and oils
Temperature range: ADCF compliant O2: 13 to 15 recommended.
at elevated temperatures.
Static: –32 to 205°C (–25 to 400°F) N2: 4.3
Low gas permeability.
Opaque, black. Dynamic (pumping): 0 to 150°C
(32 to 302°F)
†E = Excellent, G = Good, F = Fair, P = Poor, N/R = not recommended
US Toll-free: 1-800-323-4340 • Outside the US: 1-847-549-7600 • www.coleparmer.com
3 Canada 1-800-363-5900 • India 1-800-266-1244 • UK 0500-345-3000 4248