Assignment

Biosafety And Bioethics (BCH-436)

Topic:
ISAAA (GM Approval Database)

Submitted to:
Dr. Hammad Ismail
Submitted by:
Shoaib Hasan
Roll No.:
14061560-038
Class:
BS-Biotechnology
Semester:
8th
Section:
B
Department:
Biochemistry & Biotechnology
Date of Submission:
11th April 2018
 1.

Event Name: 55-1

Event Code: CUH-CP551-8

Trade Name: Rainbow, SunUp

Crop: Carica papaya - Papaya

Developer: Cornell University and University of Hawaii

Method of Trait Introduction: Microparticle bombardment of plant cells or tissue

GM Traits: Viral disease resistance , Antibiotic resistance , Visual marker

Commercial Trait: (Singular)  Disease Resistance

Summary of Basic Genetic Modification

Gene Introduced Gene Source Product Function

prsv_cp Papaya ringspot virus coat protein (CP) of confers resistance to
(PRSV) the papaya ringspot papaya ringspot virus
virus (PRSV) (PRSV) through
"pathogen-derived
resistance" mechanism
nptII  * Escherichia coli Tn5 neomycin allows transformed
transposon phosphotransferase II plants to metabolize
enzyme neomycin and
kanamycin antibiotics
during selection
uidA  * Escherichia coli beta-D-glucuronidase ( produces blue stain on
GUS) enzyme treated transformed
tissue, which allows
visual selection

Summary of Regulatory Approvals: Country, Year and Type of Approval

Food  Feed  Cultivation

Country direct use or direct use or domestic or non-
processing processing domestic use
Canada 2003    
Japan 2011   2011
United States of America 1997 1997 1996
 2.
Event Name: EMBRAPA 5.1

Event Code: EMB-PVØ51-1

Trade Name: not available

Crop: Phaseolus vulgaris - Bean, Common Bean

Developer: EMBRAPA (Brazil)

Method of Trait Introduction: Microparticle bombardment of plant cells or tissue

GM Trait: Viral disease resistance

Commercial Trait: (Singular)  Disease Resistance

Summary of Basic Genetic Modification

Gene Introduced Gene Source Product Function

ac1 (sense and Bean Golden Mosaic sense and antisense inhibits the synthesis of
antisense) Virus (BGMV) RNA of viral the viral replication
replication protein protein of the Bean
(Rep); no functional Golden Mosaic Virus
viral replication (BGMV), thereby
protein is produced conferring resistance to
the BGMV

Summary of Regulatory Approvals: Country, Year and Type of Approval

Food  Feed  Cultivation

Country direct use or direct use or domestic or non-
processing processing domestic use
Brazil 2011 2011 2011
 3.

Event Name: WKS82/130-4-1

Event Code: IFD-524Ø1-4

Trade Name: not available

Crop: Rosa hybrida - Rose

Developer: Suntory Limited (Japan)

Method of Trait Introduction: Agrobacterium tumefaciens-mediated plant transformation

GM Trait: Modified flower color

Commercial Trait: (Singular)  Modified Product Quality

Summary of Basic Genetic Modification

Gene Introduced Gene Source Product Function

5AT Torenia sp. anthocyanin 5- alters the production of
acyltransferase (5AT) a type of anthocyanin
enzyme called delphinidin
bp40 (f3'5'h) Viola wittrockiana Flavonoid 3',5'- catalyzes the production
hydroxylase (F3'5'H) of the blue-coloured
enzyme anthocyanin pigment
delphinidin and its
derivatives

Summary of Regulatory Approvals: Country, Year and Type of Approval

Food  Feed  Cultivation

Country direct use or direct use or domestic or non-
processing processing domestic use
Australia     2009 *
Colombia     2010 *
Japan     2008
United States of America     2011