Professional Documents
Culture Documents
BSHM 2B2
Module on Climatic Change
Assignment:
ASSIGNMENT
1. Explain how gene therapy works in theory.
ANSWER: Gene therapy is designed to introduce genetic material into cells to
compensate for abnormal genes or to make a beneficial protein. If a mutated gene
causes a necessary protein to be faulty or missing, gene therapy may be able to
introduce a normal copy of the gene to restore the function of the protein. A gene that
is inserted directly into a cell usually does not function. Instead, a carrier called a vector
is genetically engineered to deliver the gene. Certain viruses are often used as vectors
because they can deliver the new gene by infecting the cell. The viruses are modified so
they can't cause disease when used in people. Some types of virus, such as retroviruses,
integrate their genetic material (including the new gene) into a chromosome in the
human cell. Other viruses, such as adenoviruses, introduce their DNA into the nucleus of
the cell, but the DNA is not integrated into a chromosome.
ASSIGNMENT
Why is gene therapy research so tightly regulated?
Because of genetic engineering have yielded clear benefits with few apparent risks. Few
would question, for example, the value of our now abundant supply of human insulin
produced by genetically engineered bacteria. However, many emerging applications of
genetic engineering are much more controversial, often because their potential benefits
are pitted against significant risks, real or perceived. This is certainly the case for gene
therapy, a clinical application of genetic engineering that may one day provide a cure
for many diseases but is still largely an experimental approach to treatment.
What is the main ethical concern associated with germ-line gene therapy?
Current gene therapy research has focused on treating individuals by targeting the
therapy to body cells such as bone marrow or blood cells. This type of gene therapy
cannot be passed to a person’s children. Gene therapy could be targeted to egg and
sperm cells (germ cells), however, which would allow the inserted gene to be passed to
future generations. This approach is known as germ line gene therapy.
MULTIPLE CHOICE
At what point can the FDA halt the development or use of gene therapy?
a. on submission of an IND application
b. during clinical trials
c. after manufacturing and marketing of the approved therapy
d. all of the answers are correct
Answer: D
Module on Nanotechnology
Activities/Assignments:
Find tertiary prospectuses and industry training organization information about nanotechnology,
or show where similar resources can be found.
ANSWER: Nanotechnology is a common word these days, but many of us don’t realize the
amazing impact it has on our daily lives. According to the United States National
Nanotechnology Initiative, nanotechnology is “science, engineering, and technology conducted
at the nanoscale, which is about 1 to 100 nanometers.” One nanometer is a billionth of a meter,
or 10-9 of a meter. For comparison, a sheet of newspaper is about 100,000 nanometers thick.
Scientists are discovering that atoms and molecules behave differently at the nanoscale.
Compare nanotechnology technology courses in local and international universities using this
website.
ANSWER: Nanotechnology has recently grown by leaps and bounds to the extent that it has
been game-changing in a broad range of industries from automotive to healthcare and
everything in between. Since almost every aspect of industrial development has somehow its
roots in academia, a vast majority of universities and colleges worldwide have begun to run
specialized programs in nano science and nanotechnology, and since then they have been
attempting to equip their labs with cutting-edge research facilities and equipment for training a
new generation of skilled nanoscientists, nanotechnologists, and experts to prepare them for
nano-related careers, and to lead the rapidly-growing field of nanotechnology.
Research the technological knowledge, skills, and qualifications needed by those involved in
nanotechnology industries as compared to the different industries.
ANSWER: Nanotechnology is an interdisciplinary technology of manipulation or self-
assembly of individual atoms, molecules, or molecular clusters into structures to create
materials and devices with control geometry and at least one component below 100 nm
(nanometer) including advanced equipment that allow controlled fabrication,
measurement and visualisation with high resolution. Nanotechnology can work in the
top-down approach (which means reducing the size of the smallest structures to the
nanoscale) or the bottom-up approach (which involves manipulating individual atoms
and molecules into nanostructures and more closely integrates chemistry or biology
with microelectronics).
Module on Biodiversity and Genetically Modified Organism
ACTIVITY:
Can you mention the names of three species of plants and animals/birds found in
your locality and their importance for the residents of your locality? One example has
been done for you.
Answer: A number of species of marine turtles, including the leatherback turtle, are protected, as
are the Philippine crocodile and saltwater crocodile. The islands are home to a diverse array of
reptiles and amphibians. Water monitor lizards (Varanus salvator) of various sorts have been prized
for their skins. Skinks, geckos, and snakes are abundant, and more than 100 species are endemic to
the Philippines.