Orogel® Dental Gel

Be
nzoc
aineUS
P20%w/
w

Composition:
®
Orogel De
nta
lGe
l:Ea
chg
ramc
ont
ai
ns0.
2gmofBe
nzoc
aineUSP.

Pharmacology
Itisal oc
ala nes
thet
ic
.Loc
alanes
the
tic
sin
hibi
tc onduct
ionofnerveimpul
sesfr
om
sensor
ynerves.Thisac
ti
onr
esul
tsf
romanal
ter
ati
onoft hecel
lmembraneper
meabi
li
ty
toions.

Benzoca
inehaslows olubili
tyinwateranditisabsorbedtooslowlytobetox
ic .Al
though
poorl
yabsorbedthrought heint
actepider
mis,thisisabsorbe
df r
ommuc ou
sme mbranes.
Whe nskinpermeabili
tyha sbeenincrease
dbya brasi
onso rul c
ers
,theabsorpti
ona nd,
subse
quentl
y,theeffic
a c
yofl ocalanest
heti
csimpr oves;howe ver
,thei
nci
de nceofs i
de
eff
ect
salsoinc
reases.

Theme t
aboli
cfateoflocalane
sthe
ti
csisofg r
eatimport
anc
e,be
caus
ethe i
rtox
ici
ty
depe
ndslar
gelyonthebal
ancebe
tweenthe
irr
ate
sofabsor
pti
onandel
imi
nat
ion.

Upona bsor
ptio
nt heloca
lanes
thet
ic
sa r
eh ydrol
yze
da ndina
cti
vat
edpri
mar
il
yby a
pla
s maest
era
se,proba
blypla
smachol
ine
ster
ase.Thel
ive
ral
sopart
ici
pat
esi
nhydr
olys
is
ofloca
lanest
heti
cs.

Indication:
Fort het e
mpor a
ryr e
li
efofpai
nduet
omi
nori
njur
yori
rr
it
ati
onoft
hemo
utha
ndg
ums
li
ke-
 t ootha c
he
 s oreg ums
 c anke rsor
es
 b race s
 mi norde ntalpro
cedur
es
 d ent ure
s

Dosage and Administration:

Applytotheaff
ecte
dareaupto4timesdai
lyora sdi
rec
tedbyadoc t
or/
denti
st.Chil
dren
unde
r12ye arsofages
houldbesuper
vise
ddur i
ngtheuseofthispr
oduct
.Childrenunder
2yearsofageshoul
dbec ons
ult
edtoadoctor
/denti
stpr
iortotheus
eofthisproduct
.

Aneasyappl
ica
ti
onmightbedonebyfi
xinga
ppli
cat
oront
het ube
’sno
zzl
e.Af
ter
appl
ic
ati
on,s
uppli
edc
aps houl
dbefi
xedontopofth
eappl
ic
ator.
Precaution:
Notf orprolonge
duse.Theproductshouldnotbeusedmoretha
n7da ysun
les
sdir
ect
ed
byadoc tor /
dent
is
t.I
fcondi
ti
onpersis
tsorirr
it
ati
ondevel
ops,useoft
hepro
ducts
houl
d
bediscontinued.
Contactwi
theyesshouldbeavoide
d.

Foods
houl
dnotbet
ake
nfor1houra
fte
rus
eoft
hisme
dic
ati
oni
nmout
h.

Drug interaction:
I
nforma t
ionr egardingd
rugi
nte
rac
tioni
snotk
nown.

Side effect:
Sidee ffe
ctsa r
ele
ssc
ommon.Thes
idee
ffe
ctsi
ncl
udea
lle
rgi
es,s
wel
li
ngi
nthemou
thor
throate t
c.

Contraindication:
I
npa ti
entswhoa rehyper-
sens
it
ivet
othi
sme
dic
ati
onort
oan
yofi
tsi
ngr
edi
ent
s,ort
o
ot
her‘caine’ane s
theti
cs.

Pregnancy and lactation:

Benzocai
neha snotbe enre por
tedtocaus
ebi
rthdefe
ctsorot
herprobl
emsinpre
gna
nt
®
wome n,aswe l
la s,i
nnu r
singba bi
es.
So,Orogel c anbein
dica
tedduri
ngpreg
nan
cy
andlact
ati
on.

Storage:
Shouldb estor
edinadr
yandcoolpl
aceawayfr
omd i
rec
tsun
lig
ht.
Me dic
ine ss
houldbeke
ptou
to ft
here
achofchi
ldr
en.

How supplied:
Orogel® Dent
alGe
l:Boxc
ont
aini
ngat
ubeof5g
mBe
nzoc
aine20
% de
nta
lge
lwi
tha
n
a
ppl
ic
ato
randac
ap.