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BIOL 2061: CELL & DEVELOPMENTAL BIOLOGY
CELL STRUCTURE & FUNCTION
TUTORIAL 3 – MCQs
Lecture 4

1. What two specialized regions are essential for the establishment of a proton gradient?

A. A small region where protons can be concentrated

B. A narrower intracristal space

C. A larger internal matrix

D. An intermembrane space that is not empty, but fluid filled

E. A larger space where protons can diffuse into to create ATP

Answer: A & E

Lecture 5a

1. Dbp5 is an RNA-independent ATPase that hydrolyses ATP. In what structure does

hydrolysis result in a conformational change?

A. Gle1

B. mRNA

C. mRNP

D. NLS

E. tRNA

Answer: C

Lecture 6
 2. What targeting sequence results in protein retention in the ER lumen?

A. CNX

B. DGAT2

C. KDEL (Lys-Asp-Glu-Leu)

D. SRP

E. TIM44

Lecture 1

1. Ribosomes, a complex macromolecular machine, found within all living cells exhibit all
the following functions except:

A. The site of protein folding

B. Involved in synthesis of plant cell wall

C. Assembly of multisubunit proteins

D. Involved in the initial stages of glycosylation

E. Forms part of the secretory pathway

Answer: B

Lecture 8

1. Which of the statements describes the structure of a microtubule?

A. It has a long, hollow cylinder made of the protein tubulin ( α  and   β  t u bul i n )

B. A rope like fibre with a 10nm diameter and intermediate filament protein

C. Transmembrane proteins anchored to the cytoplasmic protein at a cell junction

D. Contains two interwind strands of actin with a diameter of 7nm

E. Fibrous proteins supercoiled into thicker cables with a diameter of 8-12nm

Answer: A

Lecture 8

1. There are over 50 intermediate filaments, divided into 6 major classes based on their size
and tissue where they are expressed. What are the names of those proteins in Type lll?

A. Neurofilaments and Nuclear Lamins

B. Nuclear Lamins and Nestins

C. Keratins and Desmin

D. Peripherin and Neurofilaments

E. Vimentin and Glial fires

Answer: E