Task 4

Epidemiological studies in environmental areas and evaluation of exposure in

health effects.

Presented to:

CATHERINE JOHANA JAIMES

Presented by:

Liana Yineth Ortega Llano

Codigo: 42016268

UNIVERSIDAD NACIONAL ABIERTA Y A DISTANCIA

DOSQUEBRADAS

NOVEMBER 12, 2019.

 1. What is the cause or environmental problem generated according to the
article and where it is developed.

In the urban área of tanneris in Hazaribagh in the city of Dhaka, Bangladesh, more
or less 7.7. Millions of liters of waste From tanneries are deposited in the
Buriganga River and Canals in Hazaribagh causing pollution.
The workers have irrigation of contamination all the time, in the river Buriganga,
also the contamination is present and is used for domestic wáter supply.
The health quality of the inhabitants is in danger; Even so, information on toxic
elements and river pollution is lacking.
Thos article is the summary of an intense study of the environmente, monitoring,
effects on human health and a relevant method of chrome contamination
remediation.

1. Which diseases can be presented by the handling of Cr according

to the article.

The diseases that Cr management can present are:

Toxic, genotoxic, mutagenic and carcinogenic effects, that cause negative health
problems. Such as skin lesions, ulceration and nasal septum perforation, eardrum
perforation, decrease espermatogénesis and lung carcinoga. Cr (VI) is classified
and Cr(III) as a Group one carcinogen and Group 3 carcinogen.

2. What is the effect of co-exposure to Cr (VI) and Cr (III)

According to the article, the biological study then showed that the coexposure to Cr
(VI) and Cr (III) in the possible proportions in the channel water in Hazaribagh
synergistically promotes the transforming activity of non-tumorigenic human
HaCaT keratinocytes with MEK / ERK and AKT activated.

The most common health problema that occurs es a exposed to chromium involves
the the respiratory tract. These effects include irritattion of the lining of the inside of
the nose, runny nose, and breathing problems.

(Keratinocytes are the predominant cells (80% -90%) of the epidermis, the most
superficial layer of the skin. They contain a very hard protein called keratin, which
stimulates the growth of epithelial cells in the skinand of the skin. that cover the
surface of the, stomach and intestines. Finally in water, the relationship should be
considered, especially when estimating potential health risks due to co-exposure to
Cr (VI) and Cr (III).
4. What is the conclusion of the study?

This article shows that the environmental problema due to contamination of toxic
materials is wide and that the precautions for disposal of toxic waste are not taken,
there is no control evidenced in the article: to mitigate and reduce pollution and
prevent diseases.

5. Sustenance why this article is relevant for the environmental

epidemiology course.

It is important for the course of epidemiology because they can recognize how
pollutants present problems in human populations, according to their geographical
location, the production characteristics of the population, the factories around. The
processes that should be tken after an epidemiological study, the ways, routes,
sources and methods can be recognized.