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MYOCARDIAL INFARCTION e.g.

STROKE

Inadequate Reperfusion Therapy


Infarction Peripheral Organs
Inadequate Coronary Blood Flow
↓ Contractility of the Ventricles Intracavity Thrombus Formation THROMBOEMBOLISM

RECCURRENT ISCHEMIA
S3 Heart Sound
Systolic Dysfunction Diastolic Dysfunction

↑ Risk for Reinfarction Ventricular Hypertrophy


↑ Ventricular Pressure Abnormal Atrial Contraction

Pressure is conveyed to the Atria Pressure is conveyed back to the


Vena Cava

Pressure is conveyed back to the


Pulmonary Veins ↑ Venous Pressure
↓ Contractility of the Ventricles

Pulmonary Congestion Pulmonary Rales KUSSMAULS’ SIGN


↑ Ischemia CARDIO
↓ Cardiac Output (Jugular Vein Distension)
-GENIC
SHOCK ↓ Lung Compliance
↓ Coronary Blood
Flow Hypotension RIGHT-SIDED HEART FAILURE
Stimulation of
Juxtacapillary Receptors
↓ Coronary Perfusion Pressure CONGESTIVE HEART FAILURE
Reflex of Rapid &
Shallow Breathing

Dyspnea
MYOCARDIAL INFARCTION ARRHYTHMIA

Electrical Instability

Transient
Prolonged
(≤48 hrs Post MI) Use of ArrhythmogenicDrugs
(>48 hrs Post MI)

e.g. Dopamine
Reentrant Circuits / Left Ventricular Dysfunction Atrial Ischemia & Distension
Enhance Automaticity of
Ventricular cells Sinus Tachycardia
Ventricular Fibrillation PAC / A-Fib

PVC / V-Tach / V-Fib


Interruption of Arterial Supply
of the Conduction Pathways

SA Node - RCA AV Node - RCA Bundle of His - LAD RBB – LAD (Proximal) LBB – LAD (Anterior)
RCA (Distal) PDA (Posterior)

SA Nodal Ischemia
AV Nodal / BB Ischemia

↑ Vagal Stimulation
↑ Vagal Stimulation

Sinus Bradycardia
HEART BLOCKS
AV Nodal Block / BB Block
Inflammation extends from MYOCARDIAL INFARCTION
Myocardium to Pericardium

Inflammation of Damaged Myocardial Phagocytic Clearance of Necrotic Tissue


Acute PERICARDITIS
Tissue extends to the Pericardium

Weakening of Ventricular Wall


Sharp Pain Fever DRESSLERS’ SYNDROME Malaise

↑ ESR Dyskinesia
Pericardial Friction Rub Pericardial Effusion Leukocytosis

Sharp & Pleuritic


Chest Pain VENTRICULAR ANEURYSM

Filling of Aneurysm Cavity


Intracavity Thrombus Formation
Stretched Myofibers During Systole

Thromboembolism
↓ Cardiac Output
Ventricular Arrhythmias

Emboli of Peripheral Organs


Heart Failure
e.g. Cerebrovascular Embolism
STROKE
MYOCARDIAL INFARCTION

Extension of the Ischemic Necrosis

Papillary Muscle Interventricular Septum

Left Ventricular Free Wall


Weakening of Papillary Muscle VENTRICULAR SEPTAL RUPTURE

Tearing of the Necrotic Myocardium


Shunting of Blood from LV to the RV
PAPILLARY MUSCLE RUPTURE
VENTRICULAR FREE WALL RUPTURE
Volume Overload of the
Loss of Valve Anchorage Pulmonary Capillaries
Hemorrhage into the Pericardium

Acute Severe Mitral Congestive Heart Failure


Regurgitation Cardiac Tamponade

↓ AP ↑ VP Distant Heart Sounds Loud systolic murmur @ the ↑ Oxygen Saturation in the
Heart Failure Pulmonary Edema
Left Parasternal Border RV than in RA.

Incomplete Tearing

PSEUDOANEURYSM

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