Week 8/Learning Guide: Bone Tissue (cont.

 Roles of Calcium and Phosphate:

o Calcium:

o Phosphate:

 Blood Calcium

o Hypocalcemia

o Hypercalcemia

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 Calcium Homeostasis
Hormone: Production: Function: Mechanism of Action:
(when, where, how (what is its role in (how does it work?)
is it produced?) the body?)

Calcitriol

Calcitonin

Parathyroid
Hormone (PTH)

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 Bone Disorders:

 Fractures:

o Stress Fracture:

o Pathological Fracture:

 Healing Stages of Fracture:

1)

2)

3)

4)

 Fracture Treatment

o Closed Reduction:

o Open Reduction:

 Osteoporosis:

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Type: Description:
Red Marrow
(myeloid tissue)

Yellow Marrow

Gelatinous Marrow

 Bone Development = Ossification or Osteogenesis

o Type Types:
 Intramembranous Bone Development:

 Endochondral Ossification:

 Metaphysis: Transitional Zones from Cartilage to Bone (5)

Zone Description
(Cartilage to Bone)

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1. Zone of
Reserved Cartilage

2. Zone of Cell
Proliferation

3. Zone of Cell
Hypertrophy

4. Zone of
Calcification

5. Zone of Bone
Deposition

 Bone Growth and Remodeling:

o Interstitial Growth:

o Appositional Growth