DRUG ACTION ADVERSE EFFECTS NSG.

RESPONSIBILITIES
VINCRISTINE SULFATE blocks cell growth by  Edema  Administered
(Brand name: stopping mitosis by  Hypo/hypertension through IV only
Vancasar PFS) interfering with  MI  Note that this
microtubule polymerization  Ischemic heart drug is
A chemotherapy drug disease contraindicated
 Neuralgia with CMT
Administered through  Paralysis syndrome
IV only  Neuropathy  Watch out for
 Deafness extravasation
 Polyuria  D/C if
 Bronchospasm extravasation
 Dyspnea occurs
 Anemia  Monitor infusion
 Leukopenia site
 Thrombocytopenia  Monitor
 Bladder dysfunction patient’s
neurological
functions
 Monitor
laboratory
values
FUROSEMIDE Inhibits the reabsorption of  ERYTHEMA  Monitor
(Brand name: Lasix) sodium and chloride from MULTIFORME electrolytes,
the loop of Henle and distal  STEVENS-JOHNSON renal and
Loop Diuretic renal tubule. SYNDROME hepatic function,
Increases renal excretion of  TOXIC EPIDERMAL serum glucose,
PO/IM/IV water, sodium, chloride, NECROLYSIS uric acid levels
magnesium, potassium, and  Photosensitivity before and
calcium.  Pruritis periodically
Effectiveness persists in  Rash throughout
impaired renal function.  Urticaria therapy
 Hypotension  Assess fluid
 Increased BUN status.
 Aplastic anemia  Monitor daily
 Agranulocytosis weight, intake
 Paresthesia and output
ratios, amount
and location of
edema, lung
sounds, skin
turgor, and
mucous
membranes.
 Notify health
care
 professional if
thirst, dry
mouth, lethargy,
weakness,
hypotension, or
oliguria occurs.
 Monitor BP and
pulse before and
during
administration.
 Geri:  Diuretic
use is associated
with increased
risk for falls in
older adults.
 Assess patients
receiving digoxin
for anorexia,
nausea,
vomiting,
muscle cramps,
paresthesia, and
aconfusion.
 Assess patient
for tinnitus and
hearing loss.
 Assess for
allergy to
sulfonamides.
 Assess patient
for skin rash
frequently
during therapy.
 Discontinue
furosemide at
first sign of rash;
may be life-
threatening.

FENTANYL Narcotic agonist-analgesic  Asthenia  Naloxone should

(Brand name: of opiate receptors; inhibits  Confusion be readily
Sublimaze, Duragesic) ascending pain pathways,  Constipation available to
thus altering response to  Dry mouth reverse the
Narcotics (Opioids) pain; increases pain  Nausea adverse effects.
threshold; produces  Somnolence  Monitor
IV/IM/TRANSDERMAL/ analgesia, respiratory  Sweating respiratory and
SUBLINGUAL SPRAY depression, and sedation  Vomiting cardiovascular
 Abdominal pain status
 Anorexia continuously
 Anxiety  Observe for
 Apnea abdominal
 Depression distention, loss
 Diarrhea of bowel
 Dyspnea sounds, or
 Euphoria urinary
 Fatigue retention.
 Hallucinations  Keep ventilatory
 Headache support (O2,
 Hemoptysis bag, mask)
 Hypoventilation available at
bedside
 Two RN
signatures are
required to
verify that the
physician order
is calculated
within
guidelines.