Tolentino,Millence Myr E.

BSN2-1

Name of Mechanism of Action Indications Contradictions Adverse reaction Nursing responsibilities

Drug
1. Ambroxol Ambroxol functions as Adjuvant therapy Should not be Gastrointestinal Monitor for S&S of
hydrochlorid a mucolytic agent. is used in used in patients disorders:  aspiration of
e Excess Nitric oxide individuals with who are known Nausea, vomiting, excesssecretions, and
(NO) has been linked aberrant, viscid, to be diarrhoea,dyspepsi forbronchospasm(unpredi
to inflammatory and or inspissated hypersensitive a, dry mouth or ctable);withholddrug and
other airway mucous to ambroxol or throat, abdominal notify
dysfunctions. NO secretions in other pain, heartburn, physicianimmediately if
promotes the acute and chronic formulation oral or pharyngeal either occur.
activation of soluble bronchopulmonar components. hypoaesthesia, •Lab tests: Monitor
guanylate cyclase and y illnesses, as dysgeusia. ABGs,
the buildup of cGMP. well as in There are no Potentially Fatal: pulmonary functions
It has been pulmonary absolute Rarely,anaphylactic andpulse oximetry as
demonstrated that complications of contraindication reactions(e.g. indicated.
ambroxol inhibits the cystic fibrosis s, but anaphylactic shock, •Have suction apparatus
NO-dependent and surgery, individuals with angioedema, rash, immediately
activation of soluble tracheostomy, stomach ulcers urticaria, pruritus). available.Increased
guanylate cyclase. andatelectasis. should exercise volume ofrespiratory tract
Inhibiting the NO- caution. fluid maybe liberated;
dependent activation suction orendotracheal
of soluble guanylate aspirationmay be
cyclase may also necessary toestablish and
control excessive maintain anopen
mucus secretion, airway.Patient & Family
lowering phlegm Education
viscosity and •Report difficulty with
improving mucociliary clearing the airway or
transport of bronchial anyother respiratory
secretions. distress

2. salbutamol Albuterol attaches to To prevent and Hypersensitivity CNS:  Check and verify
beta membrane 2 relieve to drug Anxiety,dizziness,
receptors on bronchial bronchospasm in drowsiness,headache, with doctor’s
cell membranes, which patients with hyperkinesia,insomni order and
stimulates the reversible a,irritability,nervousn
intracellular enzyme obstructive ess, tremor, vertigo, Kardex.
adenylate cyclase to airway disease weakness  Observe rights in
convert adenosine CV: medication
triphosphate (ATP) to Angina;arrhythmias,
cyclic adenosine including atrial administration
monophosphate To prevent fibrillation,extrasysto such as giving the
(cAMP). exerciseinduced les, supraventricular
This reaction asthma tachycardia, and right drug to the
decreases intracellular tachycardia; chest right patient
calcium levels. It also pain; hypertension;
using the right
increases intracellular hypotension;palpitati
levels of cAMP, as ons heck and verify
shown. Together, EENT: with doctor’s
these effects relax Altered taste, dry
bronchial smooth- mouth and throat, ear order and
muscle cells and pain, glossitis, Kardex.
inhibit histamine hoarseness,oropharyn
release. gealedema,pharyngiti  Observe rights in
s, rhinitis, taste medicationadmin
perversion
istration such as
ENDO:
Hyperglycemia GI: giving the right
Anorexia, diarrhea, drug to the right
dysphagia, heartburn,
nausea, vomiting patient
GU: UTI MS:  heck and verify
Muscle cramps
RESP: with doctor’s
Bronchospasm, order and
cough, dyspnea,
Kardex.
paradoxical
bronchospasm,  Observe rights in
pulmonary edema medication
SKIN:
Diaphoresis, administration
flushing,pallor, such as giving the
pruritus,rash,
urticaria Other: right drug to the
Angioedema, right patient
hypokalemia, using the right
infection, metabolic
acidosis route and at the
right time.
 Monitor ECG,
serum
electrolytes and
thyroid function
test results.
 Administer
 accurately
because adverse
reactions and
tolerance might
occur.
 Raise side rails
up because client
might be restless
and drowsy
because of this
drug.
