Libre, Princess Melanie S.

BSN 2-B Group 3

DRUG STUDY: OXYTOCIN and CEPHALEXIN
Name of Drug Dosage, Route, Mechanism of Indication Contraindicatio Side effects Drug-Drug Nursing
frequency Action n Interaction Responsibility

Brand Name: Induction or -Causes potent -To induce or Contraindicated -Occasional: CYCLOPROPANE Before:
OXYTOCIN Stimulation of and selective stimulate labor in patients Tachycardia, ANESTHETICS: Assess patient’s
(Pitocin) Labor stimulation of -To reduce hypersensitive premature -May cause less condition before
IV: uterine and postpartum to the drug or ventricular contractions, pronounced starting therapy
-ADULTS: 0.5– mammary gland bleeding after any o its hypotension, nausea, tachycardia but and regularly
1 milliunit/min. smooth muscle. expulsion of components. vomiting. more severe thereafter.
Classifications May gradually -Induces labor placenta Also -Rare: Nasal: hypotension During:
Pharmacologic increase in and milk ejection -Incomplete or contraindicated Lacrimation/tearing, -may cause -Monitor
class: increments of and reduces inevitable in nasal irritation, maternal sinus record
exogenous 1–2 postpartum abortion. cephalopelvic rhinorrhea, unexpected bradycardia with contractions,
hormones milliunits/min bleeding. disproportion or uterine abnormal heart rate, blood
Therapeutic q30–60 minutes delivery that bleeding/contractions. atrioventricular pressure,
class: until desired requires Adverse effects/toxic arrythmias . intrauterine
Lactation contraction conversion, as reactions: THIOPENTAL pressure, fetal
stimulant, pattern is in transverse -Hypertonicity may ANESTHETICS: heart rate, and
oxytocic established. lie; in fetal occur with tearing of -delay induction blood loss every
-Rates greater distress when uterus, increased VASOCONSTICT 15 mins
than 9–10 delivery isn’t bleeding, abruptio ORS: -be alert for
milliunits/min imminent; in placentae (i.e., placental -May cause severe adverse
are rarely prematurity; in abruption), hypertension in reactions and
required. other obstretic cervical/vaginal patients receiving drug interations
-Abortion emergencies; lacerations. caudal block -monitor fluid
IV: ADULTS: and in severe -Fetal: Bradycardia, anesthetic intake and
(Midterm toxemia, CNS/brain damage, output.
elective hypertonic trauma due to rapid Antidiuretic
abortion): 10– uterine patterns, propulsion, low Apgar effect may lead
20 total placenta score at 5 min, retinal to fluid
milliunits/min. previa, or vasa hemorrhage occur rarely. overload,
Maximum: 30 previa Prolonged IV infusion of seizures, and
units/12-hr oxytocin with excessive coma.
dose. fluid volume has caused After:
(Incomplete, severe water intoxication -assess patient’s
inevitable with seizures, coma, and family’s
abortion): 10 death. knowledge of
units as IV drug therapy.
infusion after
suction or a
sharp curettage.
Control of
Postpartum
Bleeding
IV Infusion:
ADULTS: 10–
40 units in
1,000 mL IV
fluid
IM:
ADULTS: 10
units (total
dose) after
delivery of
placenta.
Incomplete or
inevitable
abortion:
ADULTS:
10 units I.V. in
500 ml of NSS
 or dextrose 5%
in NSS.

Name of Drug Dosage, Route, Mechanism of Indication Contraindication Side effects Drug-Drug Nursing
frequency Action Interaction Responsibility

Brand Name: ADULTS: -inhibits cell wall -Respiratory -Contraindicated CNS: dizziness, PROBENICID Before:
Cephalexin -250 mg to 1g synthesis, tract, GI tract, to patients headache, malaise, -increase -Assess patient’s
P.O. q 6 hrs or promoting skin, soft tissue, hypersensitive to paresthesia. cephalon-sporin infection before
500mg q 12 hrs; osmotic bone, and joint cephalosporins, GI: abdominal level therapy
Classifications maximum, 4g instability; infections and penicillins and cramps, anal -obtain specimen
Pharmacologic daily. usually otitis media patient’s with pruritus,anorexia, for culture and
class: first For patients with bactericidal. caused by renal impairment. diarrhea, dyspepsia, sensitivity tests.
generation renal -Hinders or kills Escherichia coli glossitis, nausea,oral Begin therapy
cephalosporin impairment: susceptible and other candidiasis, pending tests
Therapeutic -if creatinine bacteria coliform bacteria, pseudomembranous results
class:antibiotic clearance is 11to group A beta- colitis, tenesmus -ask previous
40 ml/min, give hemolytic vomiting. reactions to
500mg q 8 to 12 streptococci, GU:Candidiasis, cephalosporins or
hrs; if clearance Haemophilus genital pruritus, penicillin
is 5 to 10 influenzae, vaginitis During:
ml/min; give Klebsiella, HEMATOLOGIC: -alert for
250mg q 12 hrs; Moraxella Anemia, adeverse
if clearance is catarrhalis, eosinophilia, reactions
less than Proteus mirabilis, thrombocytopenia, -if adverse GI
5ml/min, give Streptococcus transient neutropenia reactions occur,
250 mg q 12 to pneumoniae, and RESPI:Dyspnea monitor patient’s
24hrs staphylococci. SKIN:Maculopapular hydration
and erythematous After:
rashes, urticaria. Assess patient’s
OTHER: and family
anaphylaxis, serum knowledge of
sickness drug therapy