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Cellulitis and Abscess Antibiotic Table by Condition
Cellulitis and Abscess Antibiotic Table by Condition
Condition
Facial cellulitis of
Non-purulent cellulitis Purulent SSTI/ abscess Bite wounds
dental origin
Vancomycin if presumed
clindamycin resistant MRSA;
rapidly progressive lesion;
Clindamycin if cephalosporin
hemodynamic instability; ill-
allergic
appearing; failed oral Cefoxitin (transition to
clindamycin as outpatient; clindamycin AND
IV Alternatives Consider vancomycin if rapidly
abscess in an area difficult to
Clindamycin if penicillin allergic
ciprofloxacin at discharge) if
progressive lesion;
drain completely such as penicillin allergic
hemodynamic instability; ill-
face/hand/genitals
appearing
Call ID if linezolid desired
TMP/SMX if presumed
clindamycin resistant MRSA Doxycycline if age >8 years
and penicillin allergy
Doxycycline if age >8 years and
Clindamycin if cephalosporin prior clindamycin and TMP/SMX Clindamycin AND
PO Alternatives Clindamycin if penicillin allergic
allergic resistant MRSA OR presumed ciprofloxacin for penicillin
clindamycin resistance and sulfa allergic patients
allergy
Call ID for other scenarios
Call ID if linezolid desired
*Low risk criteria: Age ≥1 year; no fever; well-appearing; adequate I&D; no significant comorbidities