GENRIC NAME DOSAGE/ CLASSIFICATION INDICATION ADVERSE REACTION NURSING RESPONSIBILITY

ROUTE
Generic Name: Dosage: Antidote and  It is indicated after -hives/urticuria BEFORE:

Leucovorin 10 Detoxifying Agent high dose -nausea -observe for the 10 rights of
mg/m2 oral methotrexate therapy -vomiting drug administration
ly
in osteosarcoma and -diarrhea -can be taken with food to avoid

indicated to diminish -constipation GI upset

Route:
the toxicity and -explain to the patient it may
Oral
counteract the effects cause allergic sensitization

of impaired DURING:

methotrexate -ensure that the patient take the

elimination and of prescribed drug.

inadvertent AFTER:

overdosages of folic - Monitor serum methotrexate

acid antagonists -watch out for allergic reactions

-document the procedure

-advise to increase fluid intake

to prevent constipation