GENRIC NAME DOSAGE/ROUTE CLASSIFICATION INDICATION ADVERSE REACTION NURSING RESPONSIBILITY

Cyclosphosphamide Dosage: (Antineoplastic) - Used to treat - Cough or BEFORE

1-2 mg/kg/day Alkylating several types of hoarseness - Perform sensitivity test
(initial and cancer, it works by - Fever or chills - Tell to the client that
maintainance) agents slowing or stopping - Lower back or side amenorrhea may last up to 1
the growth of cancer pain year after cessation of
Route: cells in the body - Missing menstrual therapy
Oral - Prevent cell periods DURING
- Painful or - Give drug early in the day
division by ceoss and preferably on an empty
difficult urination stomach (if gastric irritation
linking DNA strands, is intolerable, it may be
administered with food)
thereby interfering - Advice the client that the
drug should be swallowed
with growth of whole
- Make sure that the drugs
susceptible cancer was taken, by checking the
client’s mouth
cells. AFTER
- After the administration,
advice adequate amounts of
fluid should be ingested or
infused to force diuresis to
reduce the risk of urinary
tract toxicity
- Instruct client to rest
his/her voice to prevent
hoarseness
- Advice to gargle water to
decreased pleghm/cough.
- Take tepid sponge bath to
make the client more
comfortable and will help to
minimize fever.
- Instruct to drink plenty of

fluid to keep hydrated and

prevent from urinary tract

infection disease, also to