GENRIC NAME DOSAGE/ROUTE CLASSIFICATION INDICATION ADVERSE REACTION NURSING RESPONSIBILITY

Bleomycin Dosage: 0.25 – Antineoplastic - Is a cell-cycle specific - Fever and chills BEFORE
0.5 unit/kg (10 (Antitumor drug that causes (occurring within 3 to - Perform sensitivity test
to 20 unit/m2) accumulation of cells 6 hours after a dose) - Start with a test dose. Monitor
every 1 – 2 antibiotic) - Used to treat cancer - Confusion, patient closely for at least 24
weeks - Appears to inhibit hour (vital signs, auscultation of
faintness, wheezing chest, careful observations). If
Route: DNA synthesis and to there is no acute reaction
Intravenous (less common) (hypotention, hyperpyrexia,
a lesser degree, RNA chills, confusion, wheezing,
cardiopulmonary collapse),
and protein synthesis. start regular dosage schedule.
- Instruct client to avoid spicy,
Binds to DNA, causing hot, or rough foods it may cause
GI upset
severing of single DNA - Inform client that drug may
cause hair loss but that hair will
strand. grow back after treatments ends
DURING
- Dilute each 15 U with at least
5 mL of sterile water or NS; may
be further diluted in 5 to 100
mL of the chosen diluent; do not
dilute with any solution
containing D5W
- Make sure that the drugs was
taken, by checking the client’s
mouth
AFTER
- Instruct to client/to the family
of the client to avoid OTC drugs
during antineoplastic treatment
period unless approved by
physician
- Take tepid sponge bath to
make the client more
comfortable and will help to
minimize fever
- Advice the client to lie sown

with his/her legs raised or sit