Republic of the Philippines

Cebu Normal University

Osmeña Blvd. Cebu City, 6000 Philippines

College of Nursing
Center of Excellence (COE) | Level IV Re-Accredited (AACCUP)
Telephone No.: (032) 254 4837
Email: cn@cnu.edu.ph/secretary@cnunursing.org
Website: www.cnu.edu.ph
GWYN A. ROSALES BSN-2B DRUG STUDY
Patient’s Initials: ____________________________________________________ Date of Admission: ___________________________________________
Diagnosis: _________________________________________________________ Age: _______________________________________________________
Height/ Weight: _____________________________________________________ Clinical Intervention: __________________________________________
Sex: ___________________ Ward: _______ Bed No: _______ Name of Physician: ___________________________________________

Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects Nursing Responsibilities
Generic Name: Pharmacologic Class: Ipratropium bromide is an General Indications: Hypersensitivity to CNS: dizziness,blurred vision Before
Salbutamol + Anitcholinergic anticholinergic - patients with chronic salbutamol, ipratropium 1. Check the doctor’s order
Ipratropium (parasympatholytic) agent obstructive pulmonary or fenoterol, atropine or GI: nausea, drymouth 2. Assess allergy to the drug
which, based on animal disease (COPD) on a its 3. Caution patient of the
Trade/Brand Name: studies, appears to inhibit regular aerosol derivatives.Hypertrophic Respi: different side effects
Combivent, DuoNeb, vagally-mediated reflexes bronchodilator who obstructive dyspnea,bronchospasms,horsenes 4. Obtain baseline vital
Breva Therapeutic Class: by antagonizing the action continue to have cardiomyopathy, s signs
Bronchodilator of acetylcholine, the evidence of tachyarrhythmia. 5. Prepare drugs properly at
Patients’ Dose: transmitter agent released bronchospasm and who CV: palpitations,chest pain the right dosage.
at the neuromuscular require a second Drug to Drug
junctions in the lung. bronchodilator. Interactions:Increased
Route: Anticholinergics prevent adverse effects with During
Inhalation the increases in corticosteroids, xanthine 1. Verify patient’s identity
Pregnancy Category: intracellular concentration derivatives, diuretics. 2. Explain to patient the
Form: C of Ca++ which is caused purpose of medication
by interaction of Special Precaution: 3. Advise patient to swallow
acetylcholine with the Patient’s Indication: Patient with CV medication as a whole
Maximum dose: muscarinic receptors on disorders (e.g. ischaemic 4. Give drug with full glass
<6 times/24 hours bronchial smooth muscle. heart disease, arrhythmia, of water to reduce risk of
 severe heart failure), tablet or capsule lodging in
Salbutamol relaxes severe airway the esophagus.
Minimum dose: bronchial, uterine, and obstruction, cystic 5.Do not crush, and ensure
4 times/24 hours vascular smooth muscle by fibrosis, prostatic that patient does not chew
stimulating beta 2 hyperplasia or bladder- SR preparations.
receptors. neck obstruction,
Availability: convulsive disorders,
Inhalation Solution hyperthyroidism, After
Pharmacokinetics diabetes mellitus. 1. Monitor vital signs noting
Absorption: Ipratropium: Pregnancy and lactation. hypotension andan irregular
Content: Rapidly absorbed after orabnormal pulse.
Albuterol Sulfate 2.5 mg inhalation. Bioavailability: 2. Monitor for adverse
in 3mL <10%; Salbutamol: effects.
Ipratropium Bromide 0.5 Rapidly and completely 3. Maintain aquiet,
mg in 3mL absorbed after inhalation. comfortableenvironment
Time to peak plasma tominimize anxietyand
concentration: Within 3 perhapsdecreasepalpitations.
hours. 4. Document correctly and
Distribution: Ipratropium: accordingly.
Plasma protein binding:
<20%.
Metabolism: Ipratropium:
Partially metabolised to
inactive ester hydrolysis
products; Salbutamol:
Undergoes first-pass
metabolism in the liver
and possibly in the gut
wall. Metabolised to
inactive sulfate conjugate.
Excretion: Ipratropium:
Via urine and faeces.
Terminal elimination half-
life: 1.6 hours.
Salbutamol: Via urine (as
metabolites and
unchanged drug); faeces
(small amounts).
Elimination half-life: 3-7
hours.
 Half life:
- Salbutamol: 4 hr;
Ipratropium: 2 hr
Peak:
- Salbutamol: 2-3 hr;
Ipratropium: 1-2 hr
Onset:
- Salbutamol: 15-30
minutes; Ipratropium: 5-15
minutes
Duration
-- Salbutamol: 4-8 hr;
Ipratropium: 3-6 hr

Lippincott Williams & Lippincott Williams & Lippincott Williams & Lippincott Williams & Lippincott Williams & Lippincott Williams & Wilkins. Lippincott Williams &
Wilkins. (Producer). Wilkins. (Producer). Wilkins. (Producer). Wilkins. (Producer). Wilkins. (Producer). (Producer). (2013). Nursing 2013 Wilkins. (Producer). (2013).
(2013). Nursing 2013 (2013). Nursing 2013 (2013). Nursing 2013 (2013). Nursing 2013 (2013). Nursing 2013 Drug Handbook. Philadelphia, Nursing 2013 Drug
Drug Handbook. Drug Handbook. Drug Handbook. Drug Handbook. Drug Handbook. Pa.: Handbook. Philadelphia,
Philadelphia, Pa.: Philadelphia, Pa.: Philadelphia, Pa.: Philadelphia, Pa.: Philadelphia, Pa.: Lippincott, Williams & Wilkins Pa.:
Lippincott, Williams & Lippincott, Williams & Lippincott, Williams & Lippincott, Williams & Lippincott, Williams & Lippincott, Williams &
Wilkins Wilkins Wilkins Wilkins Wilkins JONES & BARTLETT Wilkins
LEARNING. (2018). Nurses
JONES & BARTLETT JONES & BARTLETT JONES & BARTLETT JONES & BARTLETT JONES & BARTLETT Drug Handbook. SUDBURY. JONES & BARTLETT
LEARNING. (2018). LEARNING. (2018). LEARNING. (2018). LEARNING. (2018). LEARNING. (2018). LEARNING. (2018).
Nurses Drug Handbook. Nurses Drug Handbook. Nurses Drug Handbook. Nurses Drug Handbook. Nurses Drug Handbook. Nurses Drug Handbook.
SUDBURY. SUDBURY. SUDBURY. SUDBURY. SUDBURY. SUDBURY.