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0335^-36 -35563553630 32^0655360 (8)’3 6 ,32^0363(8,03-3-
2^-360 8060603360. 3000005363^0 -30600600.
162 wcom aarisnu aaanaamn unuaoanb umrrcmna
3oocn I (3)o3ob (5600b 0^060^6360 6*3636(5000)3-
(^•360, 3C?3d(5)6oo6-3c?oco 8336030 co33oocbo(8)36o,
‘60053236 83(bo650,3 6 o C50 b*3633oo)3e?*3 6 o C53-
300^0(8)360 (b*36. 4 - 23). o8,36ooc3c?,3oo63b0360ooo)
3C?o6c536o 56o6,3c?,3 6 o C5g3oo‘bo(8)g6o, 6008(^3600
^O°0 6I f 3ro33c?3836(8,ob 3008300636(8)366 (C3,C lq , C 4)
C50 IgG-b. II (B)o3ob co6oob 6o‘boe?,3 6 o 83666060
83330)60(5 &ob«j3C?0&3e?oa coo "330003b 8336 0 3
(533oocbo(8)36b ("3380C5536C10060 *30600600). 33^06-
5ooo0G(8)36ob 0 6 53C J0 3 ocoo6o"3636o C 3-ob 0 6 5 -
3(^030 056350(8,360 (83^0650*360 6500(^360).
IgA- 60? 36 m 5 Cn06 (Berger-ob (50030C5360) bo-
6000000360 IgA-ob C533ootbo(8)36ob ^330330^00600)
b'36. 4 -21. 336003060 5c?oo836‘3e?m- 93tbo65o,33'9o, 3obo 000056006(85030 33bodc?363c?oo
^i}C?36mcbo. (Robbins and Cotran Pathologic Basis of 3booc?oo(5 o3,36oo(3c?-3oo63b036(8)'3c?o 50800330^3300).
Disease, 2005.) IgA-63<36oo3oo)oo b"3 o 6 oo oboc?5o‘£>6coo obo3"3o,
n^333^ 300630030(53 803600- 06 80360^003*30?
3380(85*36006, ^0055236 36*36*3^ 3600(85306*36006 q o o
6303600^-30? 606(560086. o"33ooo)oco c33odc?3&o 506-
803 &6 6 6 m 6 n e ? 0 <3 0 6 6 G 0 '3 C?0 a e ? r) 3 0 6 ,3 -
3 0 0 )0 6 0 ^ b6,6o«3oco 8oo36oo563b3 606330680)30-
C ? n 6 0 (960<§>0 "Sgndc^g&o oyoob 8 3 0 0 6 0 (5 0 (bob(8,3~
6ob3&-36o 5c?oo336 -3 c?oo63g 6 o^)0. 8b503bo IgA-
8 * 3 6 0 (0 0 0 30 0 0 36 3 6 3 6 0 b <3006^3) 06 oqoooo3oooo,3 6 o
(03300^0(85360 "33odc?36o 5o8oo3c?o6c53b Henoch-
(3 0 6 3 3 0 ^ 0 (5 0 ), 6 n 3 3 c ? n Q o y o o g o 1 coo I I (8,o336oco.
SchOnlein-ob 3*363-36ob co6oob 603^336^0. 8300-
3 0 6 3 3 ^ 0 ( 5 0 (30 06 80 6060000(5360 6 3(36 o o cb‘3o[?o b o 5 -
60(50 IgA-G3cg6oo3oo)oo 300006(5360 c^ode^ob coo
C5600800), 6 m 3 3 c ? O Q 0 6 3 3 6 0 6o3"33oo6ob 06 oboo?-
6o6'c?0336ob (5003oco3636ob (5600b. ocoo8oo6"5o 50-
5o'£)6qoo obo3'3o, 0)06 0 6 (^ 0 3 6 3380 (8,-36 00 coo 36 ro-
(8)306 -360 0. 300036(8,000 SO /^-’Bo 10 6ge?(3o 3 0 0 ) 0 6 -
3oo3c?36oc?oo lgA-3ooc?33-3c?ob 0060 ^333C?obo (IgAl
C 5 3 6 0 0 )0 6 3 8 0 ^ 0 6 ‘3j8o6obeo6o. 8 3 0 0 6 0 (5 0 1300680 coo IgA 2), 6oo83c?o)05o6 63(36o(8)0O536*3e?oo 8boo-
■303600 b"3o 6 oo 3ootb 6 c 5 o e ? 3 6 c 3 o coo ^ 3 o d c ? 3 & o 5 0 6 - c?ooc5 IgA l. b'3o 6 oco IgAl-o)o6 36000(5 3c?o5co36o
3ocoo6(53b j6oo6o3‘3c?o o 3*36,3 6 o 3oo33c?3;jb 36ob joo33c?3336(8)ob C 3 3008300636(8)00- IgA-6n<36oo3oo)oob
cooo3oc536ob (bob(8)33,3 6 o £00)30^0 85d?*36o, B coo 5o3oo86‘333o boB’yobo 06(8)0536360 -30600600.
C 3330 (8) 0 (8) 0 , 'Sob^oobooSoo'bo, H lV - o 6 ( 3 3 ; j0 o o ) , CCj-
o6(8)0(8)6o3bo6ob C53<3o0o(8,ob, ooo3ob36oo6o bo 3-
6 0 3 6 3 3 6 0 b (J6 o o 6 o 3 ,3 c ? o c ? o 3 g o o 0 o ^ )‘3 6 o 0^3033800
coo c?o 3(3oo3o), 3oo33c?333G (8)ob 6 3 5 * 3 o?0(8,oo 6 0 0 0 -
C ?3& ob 3 3 3 3 3 o c 5 6 ‘3 c ? o C53<go0o(8)ob C56oob.
3m633mcnm500, bo6oo)c?'36o 80360063003000)
006033 (§)n^ ° Sbgogboo. 5e?oo8g6,3c?36o qdoqdo ‘feoo-
3ob (50 ^ o 6 6 ‘3x 6 3c o o o 6 o o , 6 0 0 508 00633-30? 00
33^)o65o,0 6 o (50 3.61. 36qooo3o3oc?o6*3c[?o '3 x 6 3 -
(0360b 3600(^0(3360000(7), ob333, (^30300 00(85-3 6 0
o6(3oe?(8)6o0ooa). b‘3o 6 oco ocoo6o"3636o 3 0 oo^e?^-
6 0 606330680)3063360. 5c?oo336,3c?36b 0^)36 6‘oe?o-
3003060 '3gbob3coopoc!>o, 6 0 0 508 00633*3 e? 00 33tbo6-
50-36 0 ^x^QCRO^ob 36ooc?oo336o0oocr) qoo 83^106-
50-360 3o(8)6 ojjbob 80080(8)3600) (83tbo65ooo3o3oc?o-
6 - 3 ^ 0 5 c ?00836-3(^0063(360(8)0). 6otboc?,3 6 o 838-
66060 5obd3£?36-3cnoo, 6 0 0 y33e?o%3 5080060(85*3-
e?oo 3 3 6 o ^ 3 6 o ,3c? 3o3oc?o6,3c ? 8o6y-3336"3o. 5c?oo-
9g6‘3e?36ob 3o3oe?o6g6o b"3o 6 ooo 00630530)6(B)‘3 6 3 -
600600 (30650(5 Bo6b PAS 630^0000)). 6o‘boc?,3 6 o
83866060 "330003b '3x6 3C 5 ,3C?o 3c?3336(8)36ob (83- b‘3 6 . 4 - 22. 8336 6o6oo36ooc?o(336o0o'3c?o 5Q00-
'50650-360, 36coooa)3c?,3 6 o ) C?3o3oo0o(8)-36o) fio- 836-3^0063(360(8,0. (Robbins and Cotran Pathologic
6o6o)36b (b'36. 4- 22). 32^‘3 ^ 6 o o 6 ,3c?o 3036006300- Basis o f Disease, 2005.)
 aM Q iib a a a n a a m n bfibaaanb w m n c in a n a iv o w o 1G3

b'gfo. 4 - 23. 33866o6m36mc^>o<336o0o*35^>o 55^*m336*32^m63<36o(8)ob 3£^3;j(8)6m6m56o3o. I . I (8)o 3o;

2. II (8)o3o, M - 83^0650*360 3o(8)6 ojb o, CL - 3o3oe*o6ob bo6ooi*36o, Ep - 3300132^0*380, E - 3650m-
0135^0*380. (Robbins and Cotran Pathologic Basis o f Disease, 2005.)

9m6<gme*m50d. 3ob(8)ro2*m50*36o b*36ocno 030-
2^3605300. 55^ 8 36 *32*36 0 "3godc*Q&o oymb 6m6-
802^*360, ^<153536 05^06036360 3Qtbc>650‘g 6 o *355-
6350360b 5050050360 500 36m e*o<336o0oo (3g*i>o>6-
5om3 6 m2*o<3 g 6 o0 o,35^ o 5 5^*00836*3 2*^631360(8)0)
(b‘3 6 . 4 -2 4 ), b353Q6(8),3 6 o 3 6 m5™o<336 o0 oo 3bm-
c*mco 52*^336*32^Q&ob 6of>oe*3 o (3g6m3^)6o 3 6 m-
c*o«336o0o,3c?o 52*ro3g6 ,ge^f,r)6Qg6 o(8)o), 03300010510
6c)b33o63 co3c)6 gg&o (6ob33o63 co3o6 ob36,3 6 o 55^00-
336*32*0063(360(8)0). 52*00836*3 e*36ob 3o3oc*o6 g63o
33odc*o&o 5080035^065^ cjoO^m^rt^aio, obg$),
336013060 bg53Q6(&),g 6 o bjc*o6m ‘bo. oS^Bm oje^m -
63^03600001 33(feo65o*333o 35^*0655360) IgA , 11005-
5236 C3, 360033655060, 8 0 0 6 3 60005036006001 IgG
0)6 IgM. 32?3(j66m6*32*o 3o3 6 mb3oo3oooi 0g*bo6-
50*3830 05^06036360 3cq>3d(5)6oo6*32*05!o 8336030
503300*60(8)360.
ntb n c ? 0606 ,3 c?o a o a a s ^ fn o o b 30 ad 30 <s6 3 -
^ 0 b 06c56 (T13060. 833330506*32^0 631360(8)0 606-
300050536b cno6335^>ob m55ob*36o 5000305036360b
555*3<3 b, 6 m332* o 0 boboocn5036o 52?m 336 *32* 36ob
*33o6 o(8)3bo 5ootboo636ooi. y33C£jo‘fe3 *33301 33b6o3-
51*02*00 Alport-ob bo65o6m3o 500 0^35^0 6otboex,,3-
6 0 33366060b 500)030)50360).
Alport-ob bo65g6m3o boboocn5036o 63(360(8)001,
600832*00 3 6 m 2, 6 3 booib 2,0600500b cno6335^ob
j6m6o3*35i* *3j3o>6obm6o)5o, oio>6 ob2?03b boy6*33
500 Di30)2?ob 500^00636360 (66m5^>ob 0500080, ■330560)
j0>(8)0>6o>d(8)0), 6jm30)60)b 5oob(8)6m<30o). bo33(8)m33&o
32^0650360 5-20 G'c^ob o>bo)3*9o 500 5oobo6yob3o 3m-
o0o>3b 33801(8)*36oo)b. ysse *-*^ b3 o 6 oo X J 6 m3m-
bm3o)boi0)6 33^050*35^*0 (30*1680, 6m5o3bo0 32^060-
3*360 60^6360 35^0650360 80803003630, bmc^m jo-
51*360 8(8)0)6365^360 06006 500 05^3603636001 3bm-
5^*0050 333o>(8)*36oo>. o*3(8)mbm3*36-6303bo,3c?o 500
0j*3 (8)mbm3'3 6 - 5om3o 6o(8)*3 6 o <3 m6336 o 033000100).
Alport-ob bo65o6m3o 5o3m6'33*32?oo IV (8jo 3ob 3m-
2*053&ob C^-^ocfoob 8030050063632^0 5360b (COL4A 5)
3*3 (8)000001.
dnfnync^cnQnct. 05063*32* 3^03*63 500^006360
32*0650360 3bmc*m5o 32*3d(®)6m6'3c^o 8036(^300-
3oooi 500 3mo0o3b 6ocbo5^»*36o 83866060b (00(3*3-
‘6*36 5-*b^Q2*36ob (b*36. 4-2 5 ). ^0055536 06(8)36-
b(8,o0o*32*o *3556350360 od36b jocgoo6 506356m -
164 ivowo 3dA*snb aaanaarran bnbaaanb wmmc:nand
b*gfo. 4 -2 4 . Ig A - 6 3 <g6 m 3 omoo. (R obbins and Cotran
Pathologic Basis o f D isease, 2005.)
Sob, 6 o 0 50800(3 33^3 5^>oo 630(8)6oc^'36o 0bo9g6ob
550 S^jm^nc^oboJofnocgQiob 5502,600336000 (^0030-
060 '3556325360). [5663055360b 36mg,63boobob 30-
0)0655300 336003060 b3g,936(&)‘3 6 o 550 b 6 ,0C!^o 55^00-
9g6 ,gc^rob3cc|i3 6 ro(bo, bobbci3o 5^o 6 ob b35^ 36 rocbo,
3oe*0336ob 0(8)6000300 coo o6(8)36b(Bjo00*3c*o 0306-
6 n l n . 800530063600) 6o*6o(^i'36 8386606030 0550-
6036360 g,6b^3c*36ob 256 5ocob35r«36ob ■366360b
80060035^31^60. o3*36m3ob(8)mI'jo 3ooo) £5o3obobooo>3-
6321*06 a 3, a 4 coo a 5 3mc^>6536ob 6356(8)0*360066.
0^35^0 6o‘boc*,3 6 o 83866060b 55663625366 (33-
cno5^0)3ob36oo6o 0 0 3 ^ -3 6 0 333o(8)*36oo) 35^060-
3-36025 boboococo36o ro2£ob,3 6 o obo33(8)m8-3 6 o 33-
80(8)360001, 3ro6gro5^rog)o,36oc5 30 2)CX*^336*3e?3~
5ob 60*605^-360 83866060b 2oo<3-3*6*360 500^35^13-
60m. ‘60055536 05506036360 9b-36-3'|o 06 ‘6 ^ 80360
3600(8)306*3600, 805608 cno638c?ob <3‘36 j0o o 6006-
865^*3606 500 36005600*60 306500. Alport-ob bo6-
co6ro8obo5o6 5o6bb30336om, o^os^ob 0600805^0360
c>6 0^06036360. 25003055360 50800633*32^00 IV (8)0-
3ob 3ro5^>0536ob (X3 06 a 4 550^336ob 803005506363-
C?o 536360b 8-3(8)00000).
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3025360b 33(8)o6ooc^o'63’9 o 8oo6o6'oc^3 36c6o3ob, a -
505^0j(8)oo%rc50c6o-A-ob 253<go0O(8)O, 6 0 0 50630-
6ro636‘35^>oo 3obo 8030025063635^0 5360b (X J6 o 0-
8ooboo3o’9oo) 3-3(8)00000). 25003055360 bobooo)5536o
55£?03oobcgo65oo5*v>o3o5536ob 25056003360m 01063-
8c*36’3 o, 0)305^3630, 63(8)0060080*36 6363*35^ 550
6'3C^-bobb5^>3o5^mo bob(8)33o3o. 050 35^0655360
808030036^0, ^05^360 30 3^)06365^360 06006. bo3-
3(8)m336o 063360 603330060b obo33o 550 8mo0o3b
86335^0 $30305^ob 035686360b 3025*3636ob 550b-
(8)05^-36 60605^30, 6 m332C^o0 -3o63b253&o g n ^ o -
3,C)6o C50(8)3o6m3ob 25600b 550 m6oc^ 08065530,
■^333, ^0063 *6m3ob 3m6'omo5r^m 5o8m5oyo6b 366*63.
^^85206 0^06036360 6Hm3o6ob 3385^36330, o*b6-
b,3 6 . 4 -2 5 . 3 3 8 3 3 0 2 5 6 -3 5 ^ 0 6 3 0 3 6 0 (8)0 , 6 6 *6 6 5 1 * 3 6 0
83866060b 5obj35r^36o, 35^3d(8)6m6m56o3o, C L-30-
3oe^o6 ob bo6om,3 6 o , Ep - 3300)35^0*380. (Robbins
and Cotran Pathologic Basis o f Disease, 2005.)
55360 3om3o625o*38ob o6ojo6j(8)ob 6ob3o, m o6-
38c^ob 556*6066366 06333b 3600(8)306-3606^ 30625-
3 o c^o3o2536ob 3330335^>m6ob 200 36 m 56 3b o -
636055 ,338o6obm6ob. 33085^360 5o3m35^>o6c53b
mgc^ob 5o8mym<gob 338 0 0 6 36 0 , 0635^360, 50b-
(8)6mo6(8)3b(8)o6,3 6 o bo 33(8)m336o.
d6n60dt)C?0 8C?na06,3C?n60<360t9)0 300)06-
25360 b330oo}o3,3 6 o (8jo 3ob 863633 55^>m836*3e^m-
63^6o(8)36ob 03006*63 06 2oobo6yob3o33 ^6^60.3*3-
5^00. b3o6o?5 02^06036360 o6ob330ogo3,3 6 o bo8-
3(8jm336o, 60050060000 80550b 250306530, 063800,
553606366, *6o050550 boL-,3b(8j3, 6obo0 800333366
3600(85306*3606, 30336(8)36*600, 6*600(8)3806.
8006^3002*0)500. 02^06036360 m o638c^36ob bo-
8358)60*35^0 3 3 ^ 8 ^ 3 6 6 , *632563060 2oog,3 c6,36o2o
5666*35^*3606. 5060333000b *63200306*63 do6df¥’ 366o
3 6 3 560^35^36*35^06, 836550b 8085536063 0bo3m -
3060 Jbm3oc^ob 6omc536m6o 30086(8)36*32*06. 52^00-
3o6'3CC?36ob 3ob(8)mc*m50,3 6 o 035^05^136360 5508m-
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5o8m32^o6(53b 3063351*0550 55603025360b 6 o3 6 g 6 o
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36 m5^o(g 36 o0 o,35inn 55T*m336,3 c*m63g 6 o(8)o), 338-
C?06 3omo6c536o 55^m 336 ,3 c^36 ob 3 oo2^ o 6,3 6 o m6-
2*0(8)360000, 6 0 0 oG'333b ,3 ,3556355m 3oi‘6o6m<3o-
5^*360 8ob3&ob 6'o6 3 mjj36ob ^ *3 6 . 4 - 26 ). 3005^060
oo63mo55536b 35^o*63 ob 0oc^36ob, 83*60650*360 3o(B)-
6 o jb o b , 6o^O{^i,3 6 o 83866060b 8b503bo 8obob 550
3m5^0536ob 56m 3ob. b3o6o25 aoSm b o^cjjoo 06(8)3-
6om c^36ob 250 o6(8)36o36ob b35^36m*6o, Soc^o-
3360b 0(8)6m<goo, o6(8)36b^)o0o,3c^o c3o66m*6o, 8m-
6m6*335^3*36'3556gco,3 c^o o6goc*(8)6o0oo.
 aM Q iib a a a n a a rra n bnbsoanb w m n c in a n a
egooe^o'bob ^QScoQg, b(3o 6 oeg 300006(5360 ^38-
(33C?QC?J)&0<->o: 0610360360b "So^oooio 060b
aobj3c?36o (508 00633*32? 00 0)003*60 SSS-
63(£g6ob 05o3bo l3 X <l’:>gcgg6ob coo 3 6 oo(8)goo5c?o-
30636001 3egoego6 o b(8)6 m3ob 510056(033600)),
3oc?0o*33ob njboc?0(8job 36ob(8joc?g6ob 50056003360
3oc?Ojg6bo ego o6(8)36b(8jo0o,g3‘3o > 'BgdgGoc^o 0ob-
(8),3 6 o 6o63 oo6o j 36g 6o.
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j 3c?ob rob(8)3rocoob(8)6m(3ooo)> 3o6 0 b3&o 3063*30)^
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QDO(g'3‘b‘3 6 oc?33roc?,3 6 (gotboo636ob ('36380*3(^0
363380060(8)0).
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c56536£502>0 &0 b c5 6 fr)b. bob(8)g3,3 6 o 6ocngc?o
35C?'36o bobooo)(gg6o 80)630003033 803600- 06
3oj6rob3ro3‘3 c?n 3380(8)*36000), 863033 630360(8)00),
6303600Cb*3c?n bo6co6 o)3oo), o)o6j8c?ob ^600603*3^0
*3j3o6obro6oo) coo 30336(8)36^000). 3ob(8)00c?o)50-
*36000 300006(0360 3.6. 35c?*36ob 630360^0.
Henoch-Schonlein-ob 3,3 6 3 ,36 o bobooo)(g36o ‘bgSoo
coo ^33800 joco*3636ob 5o83c?3c? '£>3(0030636^3 ego
cg*36cg*3c?36ob 635ooo6"3o 3*363*36ob 506300)063-
600), 8*30c?ob o6 g"3o ^)J03oc?oo), C536063600),
606(^030^06 bobbe^>eg36ooi, 8056000*3(^0 060)-
6oc?50oo) coo o)o6j8c?ob 060080^03600) (3 6 oo-
(8)306*3600, 333o(8j*36oo, 63g6oot£)*3cr?o bo6cg6 oo3o).
300036(8)0)0 6o6oe?c)o 300)0600360 b66o<gocg 3oo3-
6oo563b3 5C?0)336*3C?00630360(&)0 ego IgA-6303600-
3ocnoo. 3060b ^0^006360 8000003b b‘3633ocg368*3c?
33800605036b ego 8o6g36oo(£)g6gc? 3obj*3c?0(8)b cgg6-
8ob 6360c? bobbc?8oc?36’3 o, 6oo8c?36"3o0 08*3600-
tgc?i3oo63b0360ooo) 3(^0600360 IgA.
b '36. 4 -26. j6oo6oj*3c?o 5C?00336*3C?00630360(&)0.
(Dr. M.A. Venkatachalam, Dept, o f Pathology, University
o f Texas, San Antonio, TX.)
iv m x o ig s
6ojj(8,36o,3c?o 36cgoo3o6coo(8)ob cg6oob oc?o6o"3-
6360 3g8o(8)‘36oo, 3600(8)306*3600, 863033 63cg6o(»)ob
60^6360, “£>005x36 b66ogocg 3oo36oo563b3 5c?™-
3g6*3c?po6g(g6o(8)0, 336003060 ego bg53g6(8)‘3 6 o 3o-
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cgoo63(8)'3 6 o g,c?ro3g6'3e?oobje?g6o)<£)o boboooo-
(5360 0606303600cb*3c?o 3600(8)306*36000), 6303600-
<£>*3c?o bo 6cg6 o)3oo) ego ooo638e?ob j6oo6o3*3c?o
,3 33o6oboo6oo), 0^333, o6(8>36oooc?36ob 3ooc?o 6o-
^000*360 b3c?3600^00), 3035^00630360(8)00) ego
3o3oe^*36o b3c?36oo<boo) (eg0063(85*360 630360030-
0)00). 1-e?o ego 83-2 (8>o3ob (goo6g(8)ob "3g8o)b3g-
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