ACTIVE LEARNING TEMPLATE

Medication
G.H
NAME______________________________________________________

CONTENT___________________________________________________ REVIEW MODULE CHAPTER________________

TOPIC DESCRIPTOR ____________________________________________________________________________________

Enoxaparin Sodium
MEDICATION___________________________________________________________________________________________

EXPECTED Potentiates the inhibitory effect of antithrombin on factor Xa and thrombin.

PHARMACOLOGICAL
ACTION:

Therapeutic Uses
Anticoagulants
Pharmacologic: antithrombotics,
Prevention of thrombus formation.

Adverse Effects Nursing Interventions

CNS: dizziness, headache, insomnia. Assess for signs of bleeding and
GI: constipation, nausea, reversible increase in liver enzymes, hemorrhage (bleeding gums;
vomiting.
GU: urinary retention. nosebleed; unusual bruising; black,
Derm: ecchymoses, pruritus, rash, urticaria. tarry stools; hematuria; fall in
hematocrit or blood pressure;
guaiac-positive stools); bleeding
from surgical site. Notify health care
Contraindications professional if these occur.
Hypersensitivity; Hypersensitivity to benzyl alcohol
Positive in vitro test for antiplatelet antibody in the
presence of enoxaparin; Active, major bleeding.
Client Education
Advise patient to report any symptoms of
unusual bleeding or bruising, dizziness,
itching, rash, fever, swelling, or difficulty
Medication/Food Interactions breathing to health care professional
immediately.
Drug-Drug: Risk of bleeding may be by concurrent use of drugs that Instruct patient not to take aspirin,
affect platelet function and coagulation, including warfarin, aspirin, naproxen, or ibuprofen without consulting
thrombolytic agents, NSAIDs,dipyridamole, some penicillins, health care professional while on
clopidogrel, abciximab, eptifibatide, tirofiban, ticlopidine, and dextran. enoxaparin therapy.

Medication Administration Evaluation of Medication

Effectiveness
Subcut (Adults): Knee replacement surgery—30 mg q 12hr
Prevention of deep vein thrombosis and
Subcut (Adults): Outpatient—1 mg/kg every 12hrs. pulmonary embolism.
Inpatient—1 mg/kg every 12 hr or 1.5 mg/kg every 24 hr. Resolution of acute deep vein thrombosis.
Prevention of ischemic complications (with
aspirin) in patients with unstable angina or
non-Q-wave MI.

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