You are on page 1of 11

Journal of Biomechanics 34 (2001) 1065–1075

Mechanical properties of coronary stents determined by using finite


element analysis
Fre! de! rique Etavea, Ge! rard Finetb,c,*, Maurice Boivina, Jean-Claude Boyera,
Gilles Rioufolb,c, Gilbert Tholletd
a
Laboratory of Mechanics, INSA, Lyon, France
b
Department of Hemodynamics, Hospices Civils de Lyon, Claude Bernard University, Lyon, France
c
CREATIS Research Unit, CNRS, UMR 5515, INSERM, Lyon, France
d
GEMPPM, Laboratory of Scanning Electron Microscopy, INSA, Lyon, France
Accepted 14 February 2001

Abstract

The mechanical function of a stent deployed in a damaged artery is to provide a metallic tubular mesh structure. The purpose of
this study was to determine the exact mechanical characteristics of stents. In order to achieve this, we have used finite-element
analysis to model two different type of stents: tubular stents (TS) and coil stents (CS). The two stents chosen for this modeling
present the most extreme mechanical characteristics of the respective types. Seven mechanical properties were studied by
mathematical modeling with determination of: (1) stent deployment pressure, (2) the intrinsic elastic recoil of the material used, (3)
the resistance of the stent to external compressive forces, (4) the stent foreshortening, (5) the stent coverage area, (6) the stent
flexibility, and (7) the stress maps. The pressure required for deployment of CS was significantly lower than that required for TS,
over 2.8 times greater pressure was required for the tubular model. The elastic recoil of TS is higher than CS (5.4% and 2.6%,
respectively). TS could be deformed by 10% at compressive pressures of between 0.7 and 1.3 atm whereas CS was only deformed at
0.2 and 0.7 atm. The degree of shortening observed increases with deployment diameter for TS. CS lengthen during deployment. The
metal coverage area is two times greater for TS than for CS. The ratio between the stiffness of TS and that of CS varies from 2060 to
2858 depending on the direction in which the force is applied. TS are very rigid and CS are significantly more flexible. Stress
mapping shows stress to be localized at link nodes. This series of finite-element analyses illustrates and quantifies the main
mechanical characteristics of two different commonly used stents. In interventional cardiology, we need to understand their
mechanisms of implantation and action. # 2001 Elsevier Science Ltd. All rights reserved.

Keywords: Stent; Angioplasty; Finite-element analysis; Mechanics; Simulation

1. Introduction and biocompatibility. Biofunctionality defines this


ability of the device to perform the required function.
The mechanical function of a stent deployed in The clinical value of stents has been widely evaluated
a damaged artery is to provide, over the long-term, and two main advantages have been identified: (1)
a smooth, metallic tubular mesh structure that fits restenosis rates are reduced due to better initial luminal
any existing arterial curvature and that efficiently patency (Serruys and Kutryk, 1998); and (2) athero-
opposes compressive arterial forces (Sigwart, 1997). sclerotic vessel walls are rendered more mechanically
The performance of any biomedical material is con- stable (with a reduced risk of occlusion, cracking of
trolled by two sets of characteristics: biofunctionality plaque, and dissection) (Haude et al., 1991; Fishman
et al., 1991; Herrmann et al., 1992). In Europe, there are
at least 38 different types of stent currently being
*Correspondence address. Service d’H!emodynamique, Hopital #
Cardiologique, B.P Lyon-Monchat, 69394 Lyon Cedex 03, France.
marketed (Balcon et al., 1997; Serruys and Kutryk,
Tel.: +33-4-72-35-74-18; fax: +33-4-72-35-72-91. 1998): 4 of these are self-expanding and the other 34 are
E-mail address: gerard.finet@creatis.univ-lyon1.fr (G. Finet). balloon-expandable. The mechanical characteristics of

0021-9290/01/$ - see front matter # 2001 Elsevier Science Ltd. All rights reserved.
PII: S 0 0 2 1 - 9 2 9 0 ( 0 1 ) 0 0 0 2 6 - 4
1066 F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075

stents are poorly understood by interventional cardiol- 2. Methods


ogists and this has given rise to a number of
misconceptions that are at the root of various con- 2.1. Model stents
troversies. Mechanical properties vary significantly and
it is impossible to determine these, either from first We selected two stents for modeling that correspond
principles or by extrapolation. to the extremes of this wide spectrum: the most
The purpose of this study was to determine the exact representative member of the family of tubular stents
mechanical characteristics of stents. In order to achieve (TS) (Palmaz-Schatz1 stent made by Johnson and
this, we have used finite element analysis to model Johnson Company, Warren, NJ, USA) and the most
two different stents, each of which is most representative typical coil stent (Freedom1 stent made by Global
of its type, i.e., one tubular and one coil-type stent. Therapeutics Inc., Broomfield, CO, USA) (Fig. 1).
The two stents chosen for this modeling present (i) The tubular stent: The tubular stent we modeled
the most extreme mechanical characteristics of the consisted of a slotted tube of about 8 mm in length
respective types. (Palmaz-Schatz PS 1541 model). This hollow tube is

Fig. 1. Stent modeling.Tubular stent modeling. (a) Scanning electron micrograph (  43) of a Palmaz-SchatzTM stent, (b) modeled stent struts, (c) a
tubular stent modeled and visualized without thickness (thickness is taken into account in all calculations). TS1: a ¼ 0:3 mm, b ¼ 0:22 mm,
c ¼ 1:7 mm, d ¼ 0:14 mm, e (thickness)=0.1 mm, f ¼ 0:22 mm, D mounted (mean)=1.37 mm. TS2 (modified TS1}strut width): a ¼ 0:35 mm,
b ¼ 0:35 mm, c ¼ 1:57 mm, d ¼ 0:28 mm, e (thickness)=0.2 mm, f ¼ 0:34 mm, D mounted (mean)=1.37 mm.Coil stent modeling. (a0 ) Scanning
electron micrograph (  18) of a FreedomTM stent, (b0 ) modeled stent struts, (c0 ) a coil stent modeled by mean wire path and visualized without
thickness (thickness is taken into account in all calculations). CS1: h ¼ 3:2 mm, D ¼ 2 mm, d wire=0.16 mm, D (mean)=2.34 mm, d mounted
(mean)=1.37 mm. CS2 (modified CS1}the height of sinusoids is twice that of CS1): h ¼ 6:4 mm, D ¼ 2 mm, d wire=0.16 mm, D (mean)=2.34 mm,
D mounted (mean)=1.37 mm.
F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075 1067

made up of six identical units with each unit comprising WA, USA). The BCs applied to the model corespond to
two solid metal struts and two openwork struts (TS1). A radial shifts. These shifts are made on all the nodes of
second tubular stent (TS2) was modeled that had the the structure for CS and on part only for TS so as to
same overall geometry but its struts were approximatly limit flexion effects. The model was piloted with such
twice as large. shifts. The aim of the calculation was to determine the
(ii) The coil stent: The selected coil stent was in the forces arising from a given shift.
form of a single helical round wire (Freedom1 model).
We modeled two coil stents (CS) (CS1 and CS2), the 2.1.2. Materials
second had the same shape but the height (h) of its Manufacturers provide no details as to the character-
model’s sinusoid was twice that of the first. The wire of istics of the material used; there is thus no established
both these stents wrapped around the cylinder 10 times. value. The material used for this modeling was 316L
The purpose of designing two stents of different stainless steel (Z3CND17-12}Chroma 17%, Nickel
lengths from each of the two families (as shown in 12%, from the AFNOR mark) (Degallaix et al., 1992).
Figs. 1 and 2) was to investigate the impact of these A standard stress/strain curve for an annealed material
dimensions on the stents’ mechanical properties. The was used by the Abaqus1 software. The general
three-dimensional mesh remained the same (Fig. 2). mechanical properties of this material are: modulus of
elasticity E ¼ 190 MPa, Poisson coefficient n ¼ 0:3.
2.1.1. Modeling software
Modeling was performed using Abaqus1 finite 2.1.3. Modeling methodology
element software (Hibbitt, Karlsson & Sorensen, Inc., One of the salient features of Abacus software is that it
Rhode Island, USA). Since this program does not have can be adapted to deal with the mechanical parameters
an automatic grid generation, all the nodes and their of interest. Three different types of program were set up
coordinates were programmed using Visual Basic soft- to model the behavior of stents during implantation for a
ware (Windows1, Microsoft Corporation, Redmond, range of different stent deployment diameters. It is these

Fig. 2. Geometrical visualization of the different mesh structures of each of the two stent types modeled: TS and CS and the variants proposed for
each type (TS1 and TS2, CS1 and CS2). These variations illuminate the impact of these dimensions on the stent’s mechanical properties.
1068 F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075

three different types of program which were used to (b) To model stent compression, the calculation in-
calculate the mechanical parameters of interest. volves submitting each of the nodes of the variously
deployed stents (the range of different diameters in
(a) To model stent deployment, the calculation involves the programs in a) to a negative radial displacement.
submitting each of the stent’s nodes to a positive Four different calculations were performed for each
radial displacement. Eight different calculations deployment diameter which gave reductions in the
were carried out to model deployment of the stent ultimate deployed diameter of between 5% and
from its crimped position to a variety of different 25% in incremental steps of 5%.
deployment diameters (from 2 to 5.5 mm by (c) To model conformability, the stent was positioned
increasing steps of 0.5 mm). on 2 supports (located on a single generatrix) with a

Fig. 3. Representation of the various kinds of displacement of balloons and stents. (a) Balloon alone: radial displacement of a balloon corresponds to
its inflation. The relationship between diameter and inflation pressure for any balloon is supplied by the manufacturer and every balloon has a
nominal pressure (usually 6 atm) corresponding to a certain inflated diameter. (b) Stent alone: radial displacements of a stent. Both mechanical
components involved}SDP and IER}can be determined by finite element analysis. The SDP cannot be determined on a bench. (c) Stent crimped on
a balloon: inflation allows deployment of the balloon and the stent: this is the balloon inflation pressure (loading). After deflation of the balloon
(unloading), the stent undergoes IER which reduces its diameter from the inflated maximum. Subsequently, the stent is subject to further
compression by the force exerted by the arterial walls but the magnitude of this biomechanical factor is unknown. Then, the stent reaches its final
deployment diameter. The recoil measured angiographically corresponds to the sum of the two factors which tend to reduce the diameter of the stent
from its inflated maximum, i.e., the IER plus compression exerted by the diseased arterial walls.
F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075 1069

negative, radial force applied to the opposite represents the fraction of the surface of a segment
generatrix. of stented artery actually occupied by metal
for the various deployment diameters.
(6) determination of the stent flexibility. Stent stiffness
2.1.4. Modeling parameters can be calculated from the results given by the
Seven mechanical properties were studied by mathe- program in (c) (Fig. 4). This program gives the
matical modeling, the first three properties concerne the maximum radial displacement of the stent subjected
stent implantation (Fig. 3): to force F. Stiffness is given by dividing F by this
value.
(1) the pressure necessary for stent deployment (i.e., the (7) determination of stress and residual strain maps for
pressure required to achieve plastic deformation of the stents at a diameter of 3 mm.
the material used) beginning at the diameter of the
crimped stent (pressure expressed in atmosphere
with 1 atm=760 mmHg), 3. Results
(2) determination of the intrinsic elastic recoil (IER)
due to elastic deformation of the material used. This 3.1. Stent deployment pressure
recoil is expressed in terms of a relative reduction in
the diameter of the stent (%, DD=D  100) follow- Calculation of Stent deployment pressure (SDP) can
ing deflation of the balloon, be defined as the pressure applied to a stent to deploy it
(3) determination of the resistance of the stent to to the required diameter (Fig. 5). The pressure required
external compressive forces (exerted in vivo by the for deployment of CS was significantly lower than that
atherosclerotic artery). This resistance is arbitrarily required for TS (e.g., to reach a diameter of 3.5 mm,
defined as the pressure (in atm) required to reduce TS1=2.10 atm and CS1=0.71 atm; thus, over 2.8 times
the stent diameter by 10% just after its deployment greater pressure was required for the tubular model).
and its intrinsic elastic recoil. With the CS1 stent, a unique phenomenon was observed
(4) determination of the stent foreshortening. Percen- when the deployment diameter exceeded 4.5 mm: the
tage shortening can be calculated from the long- pressure suddenly began to increase, reaching 8 atm at a
itudinal displacements of the nodes at either end of diameter of 5 mm. The length of one turn of the wire was
any particular stent at the end of the running of about 5.3 mm which is, of course, lower than the
programs in (a). maximum inflation diameter. Therefore, at large infla-
(5) determination of the stent coverage area defined tion diameters, traction forces are exerted by the wire
as the ratio between the area of the stent’s which explains why a sudden increase in pressure is
external metal surface and the area of the necessary for deployment. Therefore, diameters of 5 and
arterial cylinder covered by the stent (%), which 5.5 mm should not be taken into account when dealing

Fig. 4. Geometrical visualization of the different stent deformabilities.


1070 F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075

Fig. 5. SDP for stents of between 2 and 5.5 mm. (a) TS and (b) CS. Fig. 6. IER for stents of between 2 and 5.5 mm. (a) TS and (b) CS.
Dashed lines are explained in the Section 3.

with the stress/strain curve of this type of stent. The CS2 the height of the CS1 sinusoids is one-half that of CS2.
stent (the wire of which is twice as long as that of the Therefore, a longer wire element is far more flexible.
CS1 stent) should not undergo such an increase in
inflation pressure. Moreover, the stent struts also 3.3. Determination of stent resistance to external
significantly affect this mechanical property: TS2 has compressive pressure
thicker struts and the deployment pressure required is
6.5 times greater than those required for TS1. CS2, with This external compressive pressure is in the opposite
sinusoid height twice longer that CS2, has a deployment direction to the inflation pressure and its calculation
pressure 2.7 time smaller than CS1. involves the amount of pressure to be applied to the
overall stent surface in order to deform it (Fig. 7), i.e.,
the arterial compressive pressure. Stent TS1 could be
3.2. Elastic recoil deformed by 10% at compressive pressures of between
0.7 and 1.3 atm (depending on the deployment diameter)
Once the stent had been deployed, pressure was whereas stent TS2 (which is twice as thick) was only
released to model deflation of the balloon. After release, deformed to the same extent at 8.5–20 atm, thus, the
the diameter of the stent was observed to have shrunk relationships were not linear. Lower pressures were
compared with the maximum observed at the end of required for the CS, specifically, 0.7 atm for CS1 and
inflation. This reduction in size is referred to as its IER 0.2 atm for CS2.
and is a result of elastic and plastic deformation of the
material (Fig. 6). The TS1 stent seemed far more flexible 3.4. Stent shortening
than the TS2 stent. The elastic recoil of TS1 varied
between 5.4% and 7% whereas that of TS2 was between TS1 undergoes shortening of between 0% and 11%,
3.7% and 4.1%, i.e., a two-fold difference. This was to and TS2 of between 0% and 8%. The degree of
be expected because TS1 is less thick than TS2 and shortening observed increases with deployment dia-
contains less metal and therefore shoud be more flexible. meter. CS lengthen during deployment: by a factor of
The elastic recoil of stent CS1 varied between 2.6% and between 1% and 27% for CS1 and between 0% and 8%
6.3% whereas that of CS2 was much higher for CS2. Lengthening increases with deployment dia-
(6.3–12.8%). This difference is based on the fact that meter.
F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075 1071

Fig. 8. The MCA of different stents in a stented arterial segment. (a)


Fig. 7. The resistance of stent to external compressive pressure TS and (b) CS.
(RECP) (the compressive pressure on the stent exerted by the artery).
(a) TS and (b) CS. The RECP is expressed as a function of initial
diameter (between 2 and 5.5 mm) for a given relative reduction of size
(DD=D ¼ 10%).
3.7. Stent stress maps

3.5. Stent metal coverage area After deformation of the stents modeled at 3 mm
diameter, stress mapping shows stress to be localized at
The metal coverage area (MCA) for a given stented link nodes, with significant residual values for 316L
artery segment decreases as a function of deploy- stainless steel ranging from 190 to 400 MPa (Fig. 9).
ment diameter (Fig. 8). The MCA differs widely between
the two types of stent, tubular and coil (TS1 and CS1),
being 24% and 8.75%, respectively. Moreover there 4. Discussion
are also significant differences according to design
within both families, with 24% and 48% for TS1 and The various types of stents currently on the market
TS2, and 8.75% and 17.5% for CS1 and CS2, have different intrinsic mechanical characteristics (Los-
respectively. sef et al., 1994; Flueckiger et al., 1994), but two major
types are recognized, the tubular and coil-type stents.
The deployment of most stents involves the inflation of a
balloon. The stent is mounted onto a balloon which is
3.6. Stent flexibility then inflated to generate a radial force which results in
stent deployment. The balloon, the stent, and the vessel
The ratio between the stiffness of ST1 and that of CS1 wall all interact with one another and the quality of stent
varies from 2000 to 2800 depending on the direction in deployment at a given diameter will depend on all three.
which the force is applied. The ratio for TS2 and CS2
varies from 10,200 to 14,200. Halving the thickness of 4.1. Mechanical role of the balloon
TS (TS1 and TS2) profoundly modifies flexibility
because stiffness is divided by a factor of 5. On the The pressure required to deform the balloon’s
other hand, if the height of the sinusoids of CS (CS1 and material is equal to the difference between internal
CS2) is increased, stiffness is halved. TS are very rigid (pint ) and external pressure (pext ), i.e., p ¼ pint  pext is
and CS are significantly more flexible. actually the inflation pressure therefore, pint ¼ p þ pext .
1072 F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075

Fig. 9. Stress and residual strain maps of the stents modeled at 3 mm diameter.

A linear compliance curve provided by the balloon increments of 0.5 mm. For a given diameter, the
manufacturer can be used to relate the inflation pressure manufacturer indicates a pressure value referred to as
with the corresponding diameter for balloons, which the nominal balloon inflation pressure (NBP), where
usually increase in size upwards from 0.5 mm in NBP ¼ p. This is the pressure necessary to deform the
F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075 1073

balloon structure to obtain a given diameter (Jain et al., expressed as a function of two parameters
1986). NBP is measured in water without any opposing  
1
force, i.e., pext¼ 0; therefore, pint ¼ NBP (usually 6 atm P ¼ f r3 ; ;
but also 8, 9, and 10 atm). This is an intrinsic property of l
any given balloon. where r is the wire radius and l the length of one link.
Doubling the height of the sinusoids of a coil stent
4.2. Stent mechanical considerations significantly reduced the SDPCS. For a deployment
diameter of 3.5 mm, the CS1 coil stent had a deployment
Each stent is acted upon by a radial force during pressure of 0.71 atm whereas the CS2 stent had a
deployment and, in coronary angioplasty, it is the deployment pressure of 0.25 atm.
balloon on which the stent is crimped that will provide After balloon deflation, the stent shrinks due to the
this necessary force. Therefore the stent deployment elastic recoil of the material, i.e., the IER. Such IER is a
force is the force which must be applied to the stent in phenomenon that occurs as soon as the balloon is
order to deploy it to the correct diameter. This force deflated and, although it is an inherent property that
becomes a pressure when considering the surface of the depends on the specific material and its mass, the change
stent and the SDP is a variable which depends on both in diameter differs between TS and CS because it is also
the stent type and the correct diameter. Once a stent is dependant on the three-dimensional mesh structure
mounted on a balloon, the external pressure is no longer (Barragan et al., 2000). Recoil manifests as a shrinking
zero and corresponds to the pressure required for stent following deflation of the balloon, the extent of which is
deployment, calculated on the basis of finite elements deterministic and therefore predictable (Haude et al.,
pext ¼ SDP therefore pint ¼ NBP þ SDP. In other 1993; White, 1997; De Jaegere et al., 1994). Stents thus
words, the effective or total inflation pressure for the deployed exert no radial force on the artery and resist
balloon (pint ) is equal to the sum of the pressure required any external compressive forces exerted by normal and/
to deform the balloon material (NBP) plus that required or atherosclerotic vessel walls (Schrader and Beyar,
for deployment of the stent (SDP). 1998).
The pressure required for stent deployment varies
between stents because it is dependent on the struts of 4.3. Biomechanical effects due to the artery
the wires, the specific material used, and the three-
dimensional configuration of the mesh. The struts of the The capacity to resist compressive force is the
metal wires of each stent occur in the calculation of fundamental biomechanical characteristic of any stent
deployment pressure SDP. since it corresponds to the basic therapeutic aim (Rieu
(i) For TS, limit analysis calculation gives the press- et al., 1999). Resistance to collapse is significantly
ure theoretically necessary for deployment. The different for TS and CS, being 1.5 fold higher for the
following equation gives an approximation of this former: the diameters of TS and CS shrink by 10% at
theoretical pressure for TS SDPTSwith parallepiped pressures of 1.04 and 0.75 atm, respectively (i.e., 760 and
strut section 570 mmHg). This resistance to collapse is not a constant
se ed 2 for a given stent but depends on the deployment
p¼ ; diameter. Variations are dependent on induced forces,
Dl 2
either flexion or traction forces.
where se is the material’s elasticity limit, and e, d, D, and
l are the thickness, the width, the diameter of expanded
stent, and the length of the wire, respectively. Therefore, 4.4. Adjusted balloon inflation pression (ABIP)
in order to vary the deployment pressure necessary for a
tubular stent, it is more efficient to change the width of The ABIP for stent deployment to a given diameter
the wires (a quantity which is raised to the power of 2 (to provide stenting at the same diameter as the artery,
than their thickness). The TS2 modifications in dimen- stent/artery ratio=1) is therefore dependent both on
sion (explained in figure legend 1) increased the inflation properties intrinsic to the stent and on properties of the
pressure by a factor of 5. In practice, for a deployment balloon on which the stent is mounted. ABIP is equal to
diameter of 3.5 mm, the TS1 tubular stent necessitated a the sum of the three different pressure components
deployment pressure of 2.1 atm whereas the thicker TS2 discussed above.
stent required a pressure of 13.5 atm. ABIP ¼ NBP þ SDP þ CERP;
(ii) CS are deployed owing to their plasticity by
applying a stretching force. Deformation occurs when where NBP is the nominal balloon inflation pressure,
the opposing force is equal to the force due to the SDP the stent deployment pressure determined by
elasticity limit se . Analytical calculations are impossible numerical method, and CERP the compensatory elastic
for this type of stent and the SDPCS can only be recoil pressure. IER is predictable. Its effect can be
1074 F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075

counteracted by very precise over-inflation using man- Acknowledgements


ufacturer’s balloon compliance table (CERP).
The level of balloon inflation pressure for optimal The authors greatly acknowledge R!egis Rieu, Paul
stent deployment is a controversial issue (Hausleiter Barragan, and Vincent Garitey (Ecole Sup!erieure de
et al., 1997; Goldberg et al., 1998; Glogar et al., 1997). M!ecanique de Marseille}ESM2) for their helpfull
Our study precisely demonstrates that the ABIP can be comments concerning stent mechanical properties and
accurately determined for each stent, for each required experimental validations.
diameter, and for each balloon. ABIPs should be varied
according to the variety of stents. There is no single
ABIP (high or low) that will guarantee optimal stent
sizing; however, optimal ABIP can be accurately References
determined for each stent, for each required diameter,
Balcon, R., Beyar, R., Chierchia, S., de Sheerder, I., Hugenholtz, P.G.,
and for each balloon.
Kiemeneij, F., Meier, B., Meyer, J., Monassier, J.P., Wijns, W.,
1997. Recommendations on stent manufacture, implantation and
utilization. European Heart Journal 18, 1536–1547.
Barragan, P., Rieu, R., Garitey, V., Roquebert, P., Sainsous, J.,
5. Practical implication Silvestri, M., Bayet, G., 2000. Elastic recoil of coronary stents: a
comparative analysis. Catheter and Cardiovascular Intervention
Based directly from our numerical model a new stent 50, 112–119.
has been designed and manufactured by HEXACATH Carrozza, J.P., Yock, P.G., Linnemeier, T.J., Robertson, L.K., Yock,
(Paris, France): HELISTENT1. This stent is now C.A., Schnabel, J.S., Lird, J.R., Baim, D.S., 1996. Serial expansion
of the ACS Multilink stent after 8, 12, and 16 Atm: a QCA and
commercially available in Europe. Its CE mark has IVUS pilot study. Circulation; Abstract 0509: I-88.
been obtained the 12th May 1999 under the TUV . Degallaix, S., Vogt, J.B., Foct, J., 1992. Influence de la tenue en azote
Rheinland-ID 9910735 01. The conceiving of this stent interstitiel sur le comportement en fatigue plastique oligocyclique
confirms the ability of our numerical model for d’aciers inoxydables aust!enitiques. Rupture a" chaud}GIS pro-
ceedings.
predicting mechanichal properties of coronary stents.
De Jaegere, P., Serruys, P.W., van Es, G.A., 1994. Recoil following
Wiktor stent implantation for restenotic lesions of coronary
arteries. Catheter and Cardiovascular Diagnosis 32, 147–156.
Dumoulin, C., Cochelin, B., 2000. Mechanical behavior modeling of
6. Study limitation balloon-expandable stents. Journal of Biomechanics 33, 1461–
1470.
Finite element digital simulation is a method using a Fishman, H.C., Savage, M.P., Leon, M.B., Schatz, R.A., Ellis, S.G.,
theoretical model, with all the limitations that entails. Cleman, M.W., Teirstein, P., Walker, C.M., Bailey, S., Hirshfeld,
The model uses a theoretic behavior for perfectly radial J.W., Goldberg, S., 1991. Effect of intracoronary stenting on
intimal dissection after balloon angioplasty. Journal of the
and homogeneous balloon deployment, which reality American College Cadiologists 18, 14.
fails to reproduce exactly. The model ignores any Flueckiger, F., Sternthal, H., Klein, G.E., Aschauer, M., Szolar, D.,
friction between balloon, stent and arterial wall. In the Kleinhappl, G., 1994. Strength, elasticity, and plasticity of
calculations, arterial wall visco-elasticity is not taken expandable metal stents: in vitro studies with three types of stress.
Journal of Vascular Intervention and Radiology 5, 745–750.
into account, being presently unknown.
Glogar, D., Yang, P., Hassan, A., Heyer, G., Klein, W., Luha, O.,
.
Muhlberger, V., Maurer, E., Pachinger, O., Sochor, H., Sykora, J.,
Weber, H., Weidinger, F., 1997. Does high-pressure balloon post-
dilatation improve long-term results of Wiktor1 coil stent? Journal
7. Conclusion of the American College Cardiologists; Abstract 1011-23:313A.
Goldberg, S.L., Di Mario, C., Hall, P., Colombo, A., 1998.
This series of finite-element analyses illustrates and Comparison of aggressive versus nonaggressive balloon dilatation
quantifies the main mechanical characteristics of two for stent deployment on late loss and restenosis in native coronary
different commonly used stents. Familiarity with such arteries. American Journal of Cardiology 81, 708–712.
Haude, M., Erbel, R., Hassan, I., Meyer, J., 1993. Quantitative
mechanical characteristics is important for cardiologists analysis of elastic recoil after balloon angioplasty and after
who not only have a huge range of different stents from intracoronary implantation of balloon expandable Palmaz-Schatz.
different companies to choose from but who also need to American Journal of Cardiology 21, 26–34.
understand the mechanisms of implantation and the Haude, M., Erbel, R., Straub, U., Dietz, U., Schatz, R., Meyer, J.,
1991. Results of intracoronary stents for management of coronary
action of these devices (Dumoulin and Cochelin, 2000).
dissection after balloon angioplasty. American Journal of Cardiol-
ogy 67, 691–696.
.
Hausleiter, J., Schuhlen, H., Elezi, S., Walter, M., Hadamitzky, M.,
.
Dirschinger, J., Schomig, A., 1997. Impact of high inflation
8. Uncited Reference pressures on six-month angiographic follow-up after coronary
stent placement. Journal of the American College Cardiologists;
Carrozza et al., 1996; Ruygrok and Serruys, 1996. Abstract 782-4:369A.
F. Etave et al. / Journal of Biomechanics 34 (2001) 1065–1075 1075

Herrmann, H.C., Buchbinder, M., Cleman, M.W., Fishman, H.C., stents: a comparative analysis. Catheter and Cardiovascular
Goldberg, S., Leon, M.B., Schatz, R.A., Teirstein, P., Walker, Intervention 46, 380–391.
C.M., Hirshfeld, J.W., 1992. Emergent use of balloon-expandable Ruygrok, P.N., Serruys, P.W., 1996. Intra-coronary stenting. From
coronary artery stenting for failed percutaneous transluminal concept to custom. Circulation 94, 882–890.
coronary angioplasty. Circulation 86, 812–819. Schrader, S.C., Beyar, R., 1998. Evaluation of the compressive
Jain, A., Demer, L.L., Raizner, A.E., Roberts, R., 1986. Effect of mechanical properties of endoluminal metal stents. Catheter and
inflation pressures on coronary angioplasty balloons. American Cardiovascular Diagnosis 44, 179–187.
Journal of Cardiology 57, 26–28. Serruys, P.W., Kutryk, M.J.B., 1998. Handbook of Coronary Stents,
Lossef, S.V., Lutz, R.J., Mundorf, J., Atmth, K.H., 1994. Comparison 2nd Edition.. Martin Dunitz Ltd., London.
of mechanical deformation properties of metallic stents with use of Sigwart, U., 1997. Stents: a mechanical solution for a biological
stress–strain analysis. Journal of Vascular Intervention and problem? European Heart Journal 18, 1068–1072.
Radiology 5, 341–349. White, C.J., 1997. Stent recoil: comparison of the Wiktor-GX coil and
Rieu, R., Barragan, P., Masson, C., Fuseri, J., Garitey, V., Silvestri, the Palmaz-Schatz tubular coronary stent. Catheter and Cardio-
M., Roquebert, P., Sainsous, J., 1999. Radial force of coronary vascular Diagnosis 41, 1–3.

You might also like