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Q2 / Describe the following serum glucose tests used to help confirm the
diagnosis of diabetes mellitus: casual, fasting, postprandial, and oral glucose
tolerance test.
1- Casual glucose test : ( Random blood sugar ). A blood sample will be taken at a
random time. Regardless of last ate . Random blood glucose level of 200 mg per dL (11.1
mmol per L) or greater , lower random blood glucose values (140 to 180 mg per dL [7.8 to
10.0 mmol per L]) have a fairly high specificity of 92 to 98 percent; therefore, patients
with these values should undergo more definitive testing. A low sensitivity of 39 to 55
percent limits the use of random blood glucose testing.
2- Fasting glucose test : A blood sample will be taken after an overnight fast or it is a
blood test done to measure the amount of glucose present in the blood after an eight-hour
fast. It is thus not affected by recent food intake.. A fasting blood sugar level less than 100
mg/dL (5.6 mmol/L) is normal. A fasting blood sugar level from 100 to 125 mg/dL (5.6 to
6.9 mmol/L) is considered prediabetes. If it's 126 mg/dL (7 mmol/L) or higher on two
separate tests, patient have diabetes .
3- Postprandial plasma glucose (ppg) : postprandial means after a meal; therefore,
Postprandial concentrations refer to plasma glucose concentrations after eating. Many
factors determine the Postprandial profile. In non-diabetic individuals, fasting plasma
glucose concentrations (i.e., following an overnight 8- to 10-h fast) generally range from
70 to 110 mg/dl. Glucose concentrations begin to rise ∼10 min after the start of a meal as
a result of the absorption of dietary carbohydrates. The Postprandial profile is determined
by carbohydrate absorption, insulin and glucagon secretion, and their coordinated effects
on glucose metabolism in the liver and peripheral tissues.
4- Oral glucose tolerance test : This test, patient fast overnight, and the fasting blood
sugar level is measured. Then drink a sugary liquid, and blood sugar levels are tested
periodically for the next two hours. A blood sugar level less than 140 mg/dL (7.8 mmol/L)
is normal. A reading of more than 200 mg/dL (11.1 mmol/L) after two hours indicates
diabetes. A reading between 140 and 199 mg/dL (7.8 mmol/L and 11.0 mmol/L) indicates
prediabetes
Q4/ Explain what a hemoglobin A1C (HbA1C) lab test tells the health care
provider?
Hemoglobin A1c is a measure of the degree to which hemoglobin is glycosylated in
erythrocytes and is expressed as a percentage of total hemoglobin concentration. It reflects
the exposure of erythrocytes to glucose in an irreversible and time- and concentration-
dependent manner. HbA1c levels provide an indication of the average blood glucose
concentration during the preceding 2–3 months, incorporating both pre- and postprandial
glycemia. Because blood glucose concentrations vary widely during a 24-h period and
from day to day in diabetes, the measurement of HbA1c is the most accepted indicator of
long-term glycemic control. However, the HbA1c level does not provide a measure of the
magnitude or frequency of short-term fluctuations of blood glucose, which are particularly
great in type 1 diabetes.
Q5/ How might the nurse briefly explain what diabetes is in lay terms to Mr.
and Mrs. Jenaro?
Diabetes mellitus (sometimes called "sugar diabetes") is a condition that occurs when the
body can't use glucose (a type of sugar) normally. Glucose is the main source of energy for
the body's cells. The levels of glucose in the blood are controlled by a hormone
called insulin, which is made by the pancreas
Or
Diabetes is a disease that occurs when your blood glucose, also called blood sugar, is too
high. ... Insulin, a hormone made by the pancreas, helps glucose from food get into your
cells to be used for energy. Sometimes your body doesn't make enough—or any—insulin
or doesn't use insulin well.