Analysis 5: Microalbumin Test

1. What is the most common interference in detecting microalbuminuria using Micral test?
a. Glucose concentration
b. pH value
c. temperature
d. ketonuria
e. leukocyturia
f. erythrocyturia
g. drugs
h. storage of sample
i. bacterial contamination in the urine

2. Give the reagent composition of Micral test

a. Micral-Test reagent strips contain a gold-labeled antihuman albumin antibody-enzyme
conjugate.
3. Give the other methods that can be used in detecting microalbuminuria.
a. measurement of total urine albumin in 12 or 24 h collection
i. The 24 h collection is time consuming and thus expensive and requires highly
motivated patients and careful information and it is often difficult to perform in
routine praxis
b. measurement of the albumin-to-creatinine ratio in morning urine or random sample or
measurement of urine albumin in morning urine (American Diabetes association 2005)
c. in‐office dipstick tests (semi‐quantitative)
d. widely available laboratory testing (quantitative).

Reference: Strasinger
https://pubmed.ncbi.nlm.nih.gov/9353600/
https://pubmed.ncbi.nlm.nih.gov/8242889/
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1524-6175.2004.4064.x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709962/#:~:text=Screening%20for
%20microalbuminuria%20are%20usually,(American%20Diabetes%20association%202005)