MULTIPLE CHOICE: Write the letter of the best answer on the space provided

a. A-DNA b. B-DNA c. C-DNA d. 2-DNA

1. Most common form of DNA under physiological conditions B

2. A conformational variation in DNA which has 11 base pairs per helical turn A
3. A left-handed double helix D

a. Primary b. Secondary c. Tertiary d. Quaternary

4. Level of DNA structure depends on supercoiling C

5. The sequence of bases along the pentose-phosphodiester backbone of the nucleic acid A
6. Stabilized by helix formation due to hydrogen bonding in base pairing B

a. mRNA b. tRNA c. snRNA d. siRNA

7. Site of protein synthesis C

8. Transports amino acids to site of protein synthesis B
9. Carries coded genetic information from DNA to ribosomes for protein synthesis A

a. Adenine b. Guanine c. Uracil d. Thymine e. Cytosine

10. 2-oxy, 4-amino pyrimidine E

11. 6-amino purine A
12. 2,4-dioxy, 5-methyl pyrimidine D
13. The only base found in DNA and RNA D

14. What is the base? Guanine

15. What is the sugar? Beta-2-deoxy-D-ribose
16. What is the bond that links the sugar and the base? Glycosidic bond
17. What is the bond that connects the sugar and the phosphate group? Phosphodiester bond
18. What is the name if this nucleotide? Deoxyguanosine 5’- monophosphate

19. Empty spaces crated by atom that make up the two polypeptide chains A
a. Grooves b. Active sites c. Nodes d. Cavities e. Pockets
20. DNA rich in G-C pairs contains _____ hydrogen bonds whereas a DNA rich in A-T pairs contain ____ hydrogen bonds
B
a. 2,3 b. 3,2 c. 2,1 d. 3,1
21. Which is not true of the structures of DNA? E
a. Complementary strands b. antiparallel direction c. secondary structure d. stabilized by hydrogen bonds
e. parallel direction
22. DNA rich in G-C pairs melts at ____ temperature than that rich in A-T pairs B
a. Lower b. Higher c. Same d. Uncertain
23. Enzyme involved in changing the supercoiled state of DNA A
a. Topoisomerase b. DNA gyrase c. DNA ligase d. DNAse
e. Primase
24. Bonds that joins nucleotides together to give nucleic acids D
a. N-C glycosidic bond b. N9-C1 glycosidic bond c. Phosphodiester bond
d. 3’,5’-phosphodiester bond e. none of these
25. The glycosidic bond connecting purine bases with sugars is called B
a. N1-C1 b. N9-C1 c. Both A & B d. N7-C1 e. N7-C2
26. Hydrolysis of nucleic acids yields D
a. Sugar b. Heterocyclic base c. Phosphoric acid d. all of these e. none of these
27. The inside diameter of the sugar-phosphate backbone of the DNA double helix is B
a. 10 A (Angstrom) b. 11 A c. 12 A d. 15 A e. 20 A
28. The length of one complete turn of the DNA helix along its axis is B
a. 3.4 A b. 34 A c. 11 A d. 1.1 A e. 340 A
29. What are the base pairing rules for DNA? D
a. A-G, T-C b. A-C, T-G c. A-U, C-G d. A-T, G-C e. none of these
30. Number of hydrogen bonds between adenine and thymine B
a. 1 b. 2 c. 3 d. 4
31. Which ratio is constant for DNA? B
a. A+G/T+C b. A+T/G+C c. A+C/U+G d. A+U/G+C