Name:

Date:

AS BIOLOGY ASSESSMENT
PROTEINS & DNA REPLICATION

1. How many different amino acids are used in making proteins?

A

12

20

32

2. Which parts of amino acids are involved in peptide bonds?

A. The carboxyl group on one amino acid and the side chain on the other

B. The carboxyl group on both amino acids

C. The amino group on one amino acid and the carboxyl group on the other

D. The amino group on both amino acids

3. Which part of an amino acid gives it its unique properties?

A. The amino group

B. The carboxyl group

C. The side chain

4. In a folded protein, the nonpolar (hydrophobic) amino acids tend to be:

Name:
Date:

AS BIOLOGY ASSESSMENT
PROTEINS & DNA REPLICATION

A. tucked away inside the protein.

B. exposed on the outside of the protein.

C. distributed randomly throughout the protein.

5. What provides the information necessary to specify the three-dimensional shape

of a protein?
A. The protein's peptide bonds

B. The protein's interactions with other polypeptides

C. The protein's amino acid sequence

D. The protein's interaction with molecular chaperones

6. The biological activity of a protein is determined by its:

A. peptide bonds.

B. amino acid sequence.

C. ability to form helices.

D. ability to form sheets.

7. A protein can be unfolded by a process called:

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A. renaturation.

AS BIOLOGY ASSESSMENT
PROTEINS & DNA REPLICATION

B. denaturation.

C. oxidation.

D. reduction.

8. What does the primary structure of a protein refer to?

A. The noncovalent bonds that hold the protein in a particular shape

B. Whether it has more helices than sheets in the protein

C. The amino acid sequence of the protein

D. Whether it is globular or fibrous

9. The most common covalent cross-links in proteins are sulfursulfur bonds that
form between two amino acids with SH (thiol) groups as side chains. Which amino
acid has this side chain?
A. Tryptophan

B. Methionine

C. Cysteine

D. Proline

Name:
Date:

AS BIOLOGY ASSESSMENT
PROTEINS & DNA REPLICATION

10. Consider the process that a cell uses to replicate its double-stranded DNA to
make copies for daughter cells. Which statement describes the DNA in daughter
cells?
A. The double helix in one daughter cell consists of two strands that were

originally in the parent cell, while the double helix in the other daughter cell
consists of two newly made strands.
B. The two strands of the double helices in both daughter cells consist of

segments of new and parental DNA.

C. The double helices in each daughter cell consist of one parental strand and

one newly made strand.

11. Which term describes DNA replication?
A. Conservative

B. Semiconservative

C. Dispersive

12. What kinds of bonds link the two strands of a double helix to each other?

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A. Covalent bonds

AS BIOLOGY ASSESSMENT
PROTEINS & DNA REPLICATION

B. Hydrogen bonds

C. Ionic bonds

13. DNA synthesis proceeds:

A. in 5' to the 3' direction.

B. in the 3' to 5' direction.

C. in both directions at once.

D. from the centromeres to the telomeres.

14. Nucleotides are linked by:

A. hydrogen bonds.

B. phosphodiester bonds.

C. peptide bonds.

D. ionic bonds.

15. At a replication fork, both strands of DNA are replicated in the 5'-to-3' direction.

Name:
Date:
A. True

AS BIOLOGY ASSESSMENT
PROTEINS & DNA REPLICATION

B. False

16. At a replication fork, the leading strand is synthesized:

A. continuously.

B. discontinuously.

C. first.

D. when the lagging strand is complete.

17. At a replication fork, the lagging strand is synthesized:

A. continuously.

B. discontinuously.

C. first.

D. when the leading strand is complete.

18. What is the function of single-strand binding proteins in DNA replication?

A. They unwind a DNA double helix to form two separate, single strands.

B. They bind to single-stranded DNA and assist in the re-formation of double-

stranded DNA.

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AS BIOLOGY ASSESSMENT
PROTEINS & DNA REPLICATION

C. They bind to single-stranded DNA and prevent the single-strands from re-

forming base pairs.

19. Which of the following is correct?
A. G=C
B. C=T
C. A=G
D. G=T
20. Collagen is an example of globular protein.
A. True
B. False
[Total 20 marks]