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MATERIAL SAFETY DATA SHEET

PRODUCT - MICROCRYSTALLINE CELLULOSE POWDER

Description : 1.Identification of the Substance


Status:

General Name : MICROCRYSTALLINE CELLULOSE

Trade Name : MCC

Chemical Name : Microcrystalline Cellulose

Chemical Family : Carbohydrate

Synonym : Microcrystalline Cellulose, MCC

CAS Registry No : 9004-34-6

Molecular Formula : (C6H10O5)x

Description : 2.Composition or Information on Ingredients

Composition : Name CAS # % by Weight


MCC 9004-34-6

Description : 3. Hazardous Identification

Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye
contact (irritant), of ingestion, of inhalation.

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Description : 4. First - Aid Measurement

Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with
plenty of water for atleast 15 minutes. Cold water may be used. Get medical attention if irritation occurs.

Skin Contact:
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation
develops.Cold water may be used.

Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. Getmedical attention.

Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything
by mouth to an nconscious person. If large quantities of this material are swallowed, call a physician
immediately. Loosen tight clothing such as a collar, tie, belt or waistband.

Description : 5. Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of open
flames and sparks, of heat. Non-flammable in presence of shocks.

Explosion Hazards in Presence of Various Substances: Slightly explosive in presence of open flames
and sparks.Non-explosive in presence of shocks.

Fire Fighting Media and Instructions:


SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: As with most organic solids, fire is possible at elevated temperatures
Special Remarks on Explosion Hazards:
Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a
potential dustexplosion hazard.

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Description : 6. Accident and Release Measure
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Finish cleaning by spreading water on the contaminated surface and dispose of according to local and
regional authority requirements.

Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning
by spreading water on the contaminated surface and allow to evacuate through the sanitary
system.Appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning
by spreading water on the contaminated surface and dispose of according to local and regional authority
Requirements

Description : 7. Handling and Storage

Precautions: Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire
risk, evaporate theresidue under a fume hood. Ground all equipment containing material. Do not breathe
dust.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Hygroscopic

Description : 8. Exposure Controls

Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to
keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist,
use ventilation to keep exposure to airborne contaminants below the exposure limit.
Personal Protection: Safety: Safety glasses. Lab coat. Dust respirator. Be sure to use an
approved/certified respirator or equivalent.

Description : 9. Stability And Reactivity Data

Stability: The product is stable.


Corrosivity: Non-corrosive in presence of glass.
Polymerization: Will not occur.

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Description : 10. Physic al & Chemical Properties

Physical state and appearance: Solid.


Melting Point: Decomposes.
Dispersion Properties: See solubility in water.
Solubility: Partially soluble in cold water.

Description : 11. Toxicological Information

Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects:
Skin: May cause skin irritation.
Eyes: May cause eye irritation.
Inhalation: May cause respiratory tract irritation.

Ingestion: Low hazard with normal industral usage.


The toxicological properties of this substance have not been fully investigated.

Toxicological Information
EYE EFFECTS: Minimally irritating (rabbit)
SKIN EFFECTS: Minimally irritating (rabbit)
Primary Irritation Index = 0.1/8.0
DERMAL LD50: >2 g/kg (rabbit)
ORAL LD50: >5050 mg/kg (rat)
INHALATION LC50: >0.13 mg/L/4 hr. (rat) (maximum attainable concentration, no mortality)
SENSITIZATION: (Skin) Non-sensitizing (guinea pig)
ACUTE EFFECTS FROM OVEREXPOSURE: No significant hazard in animal toxicity tests.
CARCINOGENICITY: IARC: Not listed
NTP: Not listed
OSHA: Not listed
OTHER: ACGIH: Not listed

Description : 12. Ecological Information


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Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation
products may arise.

Description : 13. Disposal Considerations

Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental
control regulations.

Description : 14. Transport Information

DOT Classification: Not a DOT controlled material (United States).


Special Provisions for Transport: To be shipped by any mode
Decompose & Ignition Temperature: as per USP 600 Degrees Celciuos
IATA : As Per IATA guidelines transport Information Not regulated

Description : 15. Regulatory Information

THRESHOLD PLANNING QUANTITY (40 CFR 370):The Threshold Planning Quantity (TPQ) for
this product, if treated as a mixture, is 10,000 lbs;however, this product contains the following ingredients
with a TPQ of less than 10,000 lbs.:

REPORTABLE INGREDIENTS (40 CFR 372):This product does not contain any toxic chemicals
subject to the reporting requirements of Section 313, Title III of the SARA (Superfund Amendments and
Reauthorization Act) of
1986.

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Description : 16. Other Information

Status:- The information presented in this MSDS is collected from published sources and
believed to be true and correct. However, the accuracy and correctness of this information
and any recommendation or suggestion made are without any warrantee or guarantee. It is
the responsibility of the user to check the correctness and act accordingly for making use of
the material.

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tel.: +91-22-23455220 | +91-22-23455354 / 55 India. info@indogulfgroup.com | pharma@indogulfgroup.com
fax: +91-22-23476536

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